Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Year range
1.
Rev. Soc. Bras. Med. Trop ; 42(3): 298-302, May-June 2009. tab
Article in Portuguese | LILACS | ID: lil-522259

ABSTRACT

Investigou-se a prevalência de infecção pela Helicobacter pylori em amostras de sangue de 100 crianças de 1 a 12 anos e de suas mães através dos métodos de hemaglutinação indireta e anti-CagA pelo ensaio ELISA. Destas 100 crianças, foram obtidas 79 amostras de fezes e realizada pesquisa de antígenos da bactéria nas fezes por ELISA de captura. Os antígenos foram detectados em 54,4 por cento (43/79) das crianças, e os anticorpos no soro em 43 por cento (34/79), métodos que apresentaram desempenhos semelhantes, com maiores discordâncias nas crianças de 1 a 4 anos. A soroprevalência nas crianças foi de 50 por cento (50/100) e nas mães de 86 por cento (86/100). Mães infectadas representaram fator de risco 19 vezes superior ao de mães soronegativas para determinar infecção em seus filhos (p < 0,05), sobretudo as mães com cepas CagA+ (p < 0,05). O contato direto pessoa-pessoa pode ser um modo de transmissão desta infecção.


The prevalence of Helicobacter pylori infection was investigated in blood samples from 100 children aged 1 to 12 years and from their mothers, by means of the indirect hemagglutination and anti-CagA methods, using ELISA assays. From these 100 children, 79 stool samples were obtained and bacterial antigens in the stools were investigated using capture ELISA. The antigens were detected in 54.4 percent (43/79) of the children, and serum antibodies in 43 percent (34/79). These methods presented similar performance, with greatest disagreement among the children aged 1 to 4 years. The seroprevalence was 50 percent (50/100) among the children and 86 percent (86/100) among the mothers. Infected mothers represented a risk factor that was 19 times greater than that of seronegative mothers, with regard to infecting their children (p < 0.05), especially the mothers with CagA+ strains (p < 0.05). Direct person-to-person contact may be a transmission method for this infection.


Subject(s)
Child , Child, Preschool , Female , Humans , Infant , Male , Antigens, Bacterial/blood , Bacterial Proteins/blood , Helicobacter Infections/transmission , Helicobacter pylori/immunology , Immunoglobulin G/blood , Brazil/epidemiology , Cross-Sectional Studies , Enzyme-Linked Immunosorbent Assay , Feces/microbiology , Hemagglutination Tests , Helicobacter Infections/diagnosis , Helicobacter Infections/epidemiology , Helicobacter pylori/isolation & purification , Prevalence
SELECTION OF CITATIONS
SEARCH DETAIL