Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma / 대한내과학회지

Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that is geographically clustered, mirroring areas endemic for human T-cell lymphotropic virus type 1 infection. Most patients with ATLL present with aggressive manifestations such as severe hypercalcemia, lymphadenopathy, hepatosplenomegaly, and bone marrow involvement with progressive thrombocytopenia. We herein report a case of a patient with ATLL exhibiting increased uptake in both lungs as shown on a bone scan using 99mTc-methylene diphosphonate. This finding is thought to have been caused by metastatic calcification associated with ectopic parathyroid hormone production.

Expression and clinical significance of osteopotin in calcified breast tissue / 中国普通外科杂志

Objective To investigate the expression of osteopontin(OPN) mRNA in breast tissues containing microcalcifications and the significance of OPN in tumor pathogenesis and metastasis of breast cancer.Methods The expression of OPNmRNA in 128 samples of tissues of breast lesions and adjacent breast tissues and 9 samples of metastatic lymph nodes were examined.Results The expression of OPNmRNA was highest in(calcified) foci of breast cancer tissues and in metastatic lynph nodes,lower in calcified foci of benign breast tissues and lowest in breast tissues adjacent to breast cancer and in benign tissues without calcification.The differences between the defferent tissues were significant(all P

The diagnostic significance of calcified thyroid nodule detected on ultrasound / 中国普通外科杂志

Objective To investigate the calcification of thyroid nodule detected on ultrasound and the relation with benign and malignant disease.Methods Data of 107 cases of malignant and 703 cases of benign(thyroid) nodules examined by high-resolution colored ultrasonography preoperatively and pathological diagnosis by paraffin embedded slides postoperatively were collected from our hospital over a period of 3 years.The(percentages) of calcification and fine stippled psammomatous(FSP) calcification in benign and malignant(nodular) disease,in different sexes and different age groups were retrospectively reviewed.Results The(incidences) of calcification and FSP calcification were significantly higher in malignant group(63.55%,(29.02%),respectively) than in benign group(P0.05).Calcification rate showed no(significant) difference between different age groups(0.05);however,there was a significant difference of the FSP calcification rate between different age groups(P

Coronary artery calcification measured with electron beam computed tomography and its correlative factors in hemodialysis patients / 中华肾脏病杂志

0),whose mean calcification score was 1935.54(0～9833). Patients with calcification score ≥100 had significantly higher morbidity of cardiovascular diseases, serum phosphate level, calcium-phosphate product, C-reactive potein concentration and lower serum albumin than patients with calcification score

Alterations of nitric oxide synthase in cardiac sarcoplasmic reticulum from rats with myocardial calcification / 中国病理生理杂志

AIM: To study alterations of nitric oxide synthase (NOS) in cardiac sarcop lasmic reticulum from rats with myocardial calcification, and to explore the mec hanism of inhibition of SR function in the rats with myocardial calcification. METHODS: The myocardial calcification rat models were prepared by vit amin D3 plus nicotine for 2 weeks and 6 weeks. Cardiac SR was separated by centrifugating. T he nitric oxide (NO) production, NOS activity and NOS protein expression in the SR were perfor med. RESULTS: Compared with control, myocardial calcium content in t he 6 weeks i ncreased by 408%(P