Calcifying Aponeurotic Fibroma in the left pectoral region in an adult: A Case report.

Calcified aponeurotic fibroma is a rare benign fibroblastic tumor. The lesion has property of local invasion and high recurrence. Because of this property, tumor should be accurately diagnosed pre-operatively. We report a case of 29 years old male, with a palpable painful mass on the anterior chest wall near left pectoral region, describes radiographic and MR findings. No skin defect was detected but patient feels discomfort. An excision procedure was done. The excised tissue was sent for biopsy and calcified aponeurotic fibroma was diagnosed

Gaint Calcifying Aponeurotic Fibroma of Web Space: Case Report with Review of Literature

Calcifying aponeurotic fibromais an uncommon,benign fibroblastic tumor which has a preference forneighborhood invasion and a high relapse rate.Henceforth, precise preoperative analysis andcomplete extraction are imperative to counteract therecurrence of the tumor after careful surgical removal.We report a case of 75 year old man with left hand firstweb space calcified aponeurotic fibroma with distinctradiological and MRI features.

Calcifying Aponeurotic Fibroma of the Knee: a Case Report with Radiographic and MRI Finding

Calcifying aponeurotic fibroma (CAF) is an uncommon benign tumor and a locally aggressive fibroblastic lesion. It commonly affects the palmar side of the hand and fingers, and the soles of the feet. The typical clinical manifestations are known as a poorly circumscribed, slow-growing, and asymptomatic firm mass. Most CAFs usually reveal low to intermediate or isointensity on T1-weighted images, and strong heterogeneous enhancement. However, various signal intensities on T2-weighted images have been reported depending on the degree of hypocellularity or the amount of calcification or collagen within the tumor. This report provides the radiographic and MRI finding of CAF arising in uncommon site, the knee region, of a 19-year-old male who presented with a painful and palpable mass.

Clinicopathological features of six cases of calcifying aponeurotic fibroma / 临床与实验病理学杂志

Purpose To investigate the clinicopathologic features of calcifying aponeurotic fibroma (CAF). Methods The clinical and pathologic profiles of 6 cases of CAF were retrospectively analyzed. Results CAF appeared a firm, painless and slowly growing mass with a predilection for the distal portions of the extremities in young children and adolescents. Microscopically, the tumor consis-ted mainly of benign appearing spindle cells, chondroid cells and calcific debris. Immunohistochemically, the tumor cells were positive for vimentin, HHF-35, S-100, Calponin and CD68. Conclusion CAF is a rare, locally aggressive fibroblastic lesion. It can make an accurate diagnosis by integrating the clinical location with histopathological features. Repeated minor trauma to the extremities and some embryologic cell nests maybe its pathogenesis.

Calcifying Aponeurotic Fibroma: Case Report with Radiographic and MR Features

Calcifying aponeurotic fibroma is a rare, benign fibroblastic tumor. The lesion has a propensity for local invasion and a high recurrent rate. Therefore, accurate preoperative diagnosis and complete excision are important to prevent the recurrence of the tumor after surgical removal. However, radiographic and magnetic resonance imaging findings of calcifying aponeurotic fibroma have been extremely rarely described in the radiology literature. Thus, we report a rare case of calcifying aponeurotic fibroma affecting the dorsal wrist in a 67-year-old man, describe radiographic and MR findings, and discuss the differential diagnosis of the tumor.

Calcifying Aponeurotic Fibroma with Gait Disturbance Caused by Trauma / 대한피부과학회지

A calcifying aponeurotic fibroma is a rare benign fibrous tumor with well-characterized histopathological features. Calcifying aponeurotic fibromas are generally slowly-growing lesions related to tendons and aponeuroses in the distal extremities of children and adolescents. While the neoplasm is usually asymptomatic, cases of progressive local discomfort have been reported. The exact etiology of this neoplasm is unknown, and there is frequently no history of trauma or local irritating factors. A 10-year-old female presented with a 2.5x2.0 cm, subcutaneous mass on the right sole 4 years after she bumped against a table. The histopathologic examination showed a poorly circumscribed fibrotic mass with foci of chondroid differentiation and calcification. These findings were consistent with the diagnosis of a calcifying aponeurotic fibroma. After total excision of the mass, there has been no recurrence of the lesion in 8 months of follow-up.

Calcifying Aponeurotic Fibroma: An Atypical Case

Calcifying aponeurotic fibroma is a very rare benign soft tissue tumor with predilection for the fingers and palms of children and adolescents. We describe an unusual case of a calcifying aponeurotic fibroma in old age that circumferentially involved the dorsal and palmar side of the third metacarpal head.We performed a wide excision using two incisions, resulting in satisfactory clinical result. A calcifying aponeurotic fibroma must be considered in the differential diagnosis of a calcifying soft tissue lesion occuring in the hand of old age.

A Case of Calcifying Aponeurotic Fibroma in an Adult / 대한피부과학회지

Calcifying aponeurotic fibroma is an unusual, but well-characterized soft tissue tumor that typically involves the extremities. The age at presentation ranges from birth to 64 years of age. However, the majority of cases are seen in children with a median age of 12 years. Histologically, this tumor shows a poorly circumscribed, fibrotic mass extending into fat with areas of dense hyalinization, fibrosis and scattered calcification. Due to its infiltrative growth, calcifying aponeurotic fibroma has a high rate of local recurrence after surgical treatment. We recently encountered a 53-year-old Korean man with a solitary, hyperkeratotic, subcutaneous nodule on the sole of his foot. After histopathologic examination, the lesion was diagnosed as calcifying aponeurotic fibroma. During the follow-up period for 3 months, there was no increase in size of the lesion.

Calcifying Aponeurotic Fibroma with Osseous Involvement of the Finger: a Case Report with Radiologic and US Findings

Calcifying aponeurotic fibroma is a rare soft tissue tumor that occurs in the distal extremities of children and adolescents. We report ultrasound and X-ray findings of a calcifying aponeurotic fibroma in the finger of a 36-year-old woman, associated with distal phalangeal bone involvement.

Calcifying Aponeurotic Fibroma Occurring on the Chin: A Case Report

PURPOSE: Fewer than 100 cases of calcifying aponeurotic fibroma have been reported in the literature since this entity was initially described by Keasbey in 1953 who called it calcifying juvenile aponeurotic fibroma. The tumor is a slowly growing, painless mass. In most cases the mass is poorly circumscribed and causes neither discomfort nor limitation of movement. Most lesions occur in children, with a peak incidence ages of 8-14 years. There is no evidence of any increased familial prevalence. Predilection sites are palm, finger, toe, but it also occurs in the wrist, forearm, elbow, upper arm, neck, abdominal wall, lumbar paravertebral area, leg and ankle. We herein describe a rare case of calcifying aponeurotic fibroma occurring on the chin with review of the literature. METHODS: A 14-year-old male had painless, slowly growing mass(phi2.5cm) on a chin for a year. The tumor was excised elliptically under local anesthesia and the excisional site was repaired directly. Due pathological examination was processed. RESULTS: Histological examination revealed an ill- defined fibrous growth that extends with multiple processes into the surrounding tissue with centrally located foci of calcification. The tumor is composed of short spindled plump fibroblasts with round or ovoid nuclei separated by collagenous stroma, showing vaguely palisading pattern. Diagnosis of calcifying aponeurotic fibroma was conferred. Postoperatively, the patient did well, and the lesion had not recurred. CONCLUSION: Fewer than 100 cases of calcifying aponeurotic fibroma have been reported in the literature. The most common occurring sites are palm, finger & toe, but it has been reported in the wrist, forearm, elbow, upper arm, neck, abdominal wall, lumbar paravertebral area, leg and ankle. Two cases of calcifying aponeurotic fibroma occurring on the neck have been reported in the literature. To the authors knowledge, our case of calcifying aponeurotic fibroma occurring on the chin is the first to be reported.

A Case of Calcifying Aponeurotic Fibroma with Gait Disturbance / 대한피부과학회지

Calvus, callus, plantar warts and piezogenic papules are well known to cause discomfort and disturbance of gait in ordinary physical and sports activities. Furthermore, calcifying aponeurotic fibroma, whose mass slowly grows on the palms and soles of children and young adults, leads to pain, disturbance of gait, and even to skeletal deformities. A 22-year-old woman noticed an elevated subcutaneous mass on the left plantar surface of her big toe, which was accompanied with pain, tenderness and gait disturbance. The histologic findings showed an ill-circumscribed fibroblastic proliferation with foci of calcification and chondroid differentiation. After total excision of the mass, the patient became free of the above symptoms and the lesion did not recur for 9 months.

Calcifying Aponeurotic Fibroma: A Case Report / 영남의대학술지

Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that usually involves distal extremities in children and adolescents, especially the hands and feet. We report a case of calcifying aponeurotic fibroma arising in a 14-year-old boy who complained of right thumb mass. Surgical excision was performed. The resected specimen showed a 2.0x1.5 cm grayish white, fibrotic tissue. Histologic examination showed proliferation of fibroblastic cells with infiltrative growth pattern. Foci of calcification and chondroid differentiation were present.

Calcifying Aponeurotic Fibroma: A Case Report / 영남의대학술지

Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that usually involves distal extremities in children and adolescents, especially the hands and feet. We report a case of calcifying aponeurotic fibroma arising in a 14-year-old boy who complained of right thumb mass. Surgical excision was performed. The resected specimen showed a 2.0x1.5 cm grayish white, fibrotic tissue. Histologic examination showed proliferation of fibroblastic cells with infiltrative growth pattern. Foci of calcification and chondroid differentiation were present.

A Case of Calcifying Aponeurotic Fibroma / 대한피부과학회지

Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that primarily occurs in children and adolescents and has a strong predilection for the distal portion of the extremities and has a tendency to recur. A case of calcifying aponeurotic fibroma arising in the tip of 2nd digit of right hand of 24-year-old woman was presented. The lesion was solitary, 0.5X0.5cm sized, mildly tender, erythematous papule. Microscopic finding showed poorly circumscribed proliferation of dense fibrous tissue containing epihelioid-like fibroblasts, islands of metaplastic chondroid differentiation with focal calcification.

A case of calcifying aponeurotic fibroma / 대한피부과학회지

Calcifying aponeurotic fibroma is a rare benign tumor found primarily on the hands or wrists of children and adolescents. It has a tendency of local invasion, and a high recurrence rate after excision. An 11-year-old boy had a hard indurated. 3 x 3cm-sized, nodule on the right sole for 3 years. A biopsy specimen showed heavy focal calcification within areas of densely paked stromal fibroblastic cells. Some fields contained multinucleatec giant cells and chondroid metaplasia. There were infiltrative growth patterns of fibroblastic cells extending into the adjacent adipose tisse and blood vessels. There was no evidence of reccurence at 3 months after the operation.