Calcifying odontogenic cyst with AOT-like features: a case report and literature review / Cisto odontogênico calcificante com características adenomatóides: relato de caso e revisão de literatura

Odontogenic lesions are a heterogeneous group of diseases that presents differences in their biological behavior and the occurrence of variable inductive interactions. Calcifying odontogenic cyst (COC), or Gorlin's cyst, is a well-recognized example of these lesions. We describe a case of COC with AOT-like areas and highlights its morphological diversity. A 60-year-old pheoderma man presented with a large swelling in the anterior buccal region of the mandible. Panoramic radiography revealed a well-defined, unilocular, radiolucent lesion associated with important root resorption. Complete enucleation of the lesion was performed and the histopathological findings met the criteria for the diagnosis of COC, although the cyst exhibited unusual AOT-like features. The patient has been recurrence free for 6 months after surgery. COCs with AOT-like features are rare, and reflect the multipotentiality and complexity of the inductive effects of the odontogenic epithelium with the ectomesenchyme. Enucleation seems to be the most indicated treatment, similar to classical COC (AU)

As lesões odontogênicas são um grupo heterogêneo de patologias que apresentam diferenças no seu comportamento biológico, e ocorrência de interações indutivas variáveis. O cisto odontogênico calcificante (COC), ou cisto de Gorlin, é um exemplo bem conhecido destas lesões. Descrevemos um caso de COC com áreas adenomatóides e destacamos a sua diversidade morfológica. Paciente do sexo masculino, 60 anos de idade, apresentou um aumento de volume na região anterior da mandíbula. A radiografia panorâmica revelou uma lesão bem definida, unilocular e radiolúcida associada a uma reabsorção radicular importante. A enucleação completa da lesão foi realizada e os achados histopatológicos preencheram os critérios para o diagnóstico de COC, embora o cisto exibisse características adenomatóides pouco usuais. O paciente permanece livre de recidivas durante 6 meses após a cirurgia. Os COCs com características adenomatóides são raros, e refletem a multipotencialidade e complexidade dos efeitos indutivos do epitélio odontogênico com o ectomesênquima. A enucleação parece ser o tratamento mais indicado, semelhante ao COC clássico. (AU)

Quiste odontogénico calcificante asociado a odontoma complejo en la región posterior del maxilar. Reporte de caso clínico y revisión de la literatura / Calcifying odontogenic cyst associated with complex odontoma in the posterior litera of the maxilla. A case report and review of the literature

El quiste odontogénico calcificante (QOC) es raro y representa <1% de todos los quistes odontogénicos, pertenece a las lesiones conocidas como "tumores de células fantasma", estos son una familia de lesiones que varían en presentación clínica de quiste o neoplasia sólida, en su comportamiento biológico de benigno a localmente agresivo o metastásico, esta diversidad ha generado extenso debate sobre la clasificación, terminología, manejo y pronóstico de estas patologías. Presentamos el caso clínico de un paciente masculino de 17 años de edad con diagnóstico de quiste odontogénico calcificante asociado a odontoma complejo situado en la región posterior del maxilar, en la literatura existen reportados solo 27 casos de QOC en esa zona. Fue tratado mediante enucleación quirúrgica, curetaje, rotación de almohadilla grasa bucal y colocación de malla de titanio para reconstruir la pared anterior del seno maxilar. El control postoperatorio clínico y radiográfico a 12 meses no muestra recidiva de la lesión además exhibe un excelente resultado funcional y estético, esto nos permite concluir que el tratamiento fue adecuado. Realizamos una revisión de la literatura en Science Direct, PubMed y Biblioteca Cochrane, con objeto de informar las características clínicas, histopatológicas, radiográficas y el tratamiento de estas lesiones.

The calcifying odontogenic cyst (COC) is rare and represents <1% of all odontogenic cysts, it belongs to the lesions known as "ghost cell tumors", these are a family of lesions that vary in clinical presentation of cyst or solid neoplasia, in their behavior biological from benign to locally aggressive or metastatic, this diversity has generated extensive debate on the classification, terminology, management and prognosis of these pathologies. We present the clinical case of a 17-year-old male patient with a diagnosis of calcifying odontogenic cyst associated with a complex odontoma located in the posterior region of the maxilla, in the literature there are only 27 reported cases of (COC) in that area, he was treated by surgical enucleation, curettage, rotation of the buccal fat pad and placement of titanium mesh to reconstruct the anterior wall of the maxillary sinus. The clinical and radiographic postoperative control at 12 months does not show recurrence of the lesion, in addition it exhibits an excellent functional and aesthetic result, this allows us to conclude that the treatment was adequate. We conducted a review of the literature in Science Direct, PubMed and Cochrane, in order to report the clinical, histopathological, radiographic characteristics and the treatment of these lesions.

Large calcifying odontogenic cyst in the posterior maxilla / Extenso cisto odontogênico calcificante em maxila posterior

RESUMEN La aparición de un quiste odontogénico calcificante (QOC) en la región posterior de la maxila es infrecuente; hay pocos informes descritos en la literatura. Presentamos el caso de una paciente de 13 años que presentó una lesión extensa en la maxila izquierda (> 7,5 cm). La radiografía panorámica mostró una lesión radiolúcida unilocular bien delimitada, que se extendía desde el maxilar posterior izquierdo hasta el seno maxilar. La paciente fue sometida a descompresión, seguida de de la extirpación quirúrgica conservadora de la lesión. El análisis histológico de la pieza quirúrgica confirmó el diagnóstico de QOC. Después de un año, no se observaron recurrencias. La paciente permanece en seguimiento regular.

Exophytic gingival growth of the maxillary canine region in a young individual: Extremely rare case report of peripheral dentinogenic ghost cell tumor

The present case report is a case of peripheral dentinogenic ghost cell tumor (PDGCT), an extremely rare solid benign neoplastic variant of calcifying cystic odontogenic tumor of the gingiva mimicking clinically as pyogenic granuloma, fibroma, peripheral ossifying fibroma, and peripheral giant-cell granuloma. A 24-year-old male reported with painless, firm, solitary, sessile, smooth-surfaced, nonulcerative, nonpulsatile, well-defined swelling measuring ≈12 mm × 9 mm in the interdental gingiva of the teeth #13 and #14 extending to the mucogingival junction. Intraoral periapical radiographic showed a normal trabecular pattern with mild radiolucency without bony expansion, periapical lesion, and resorption of the adjacent teeth. The diagnosis was established by histopathologic examination. Very few cases of this entity have been documented in the literature. The present case report aims to document this rare entity and emphasizes on the fact that histopathological examination of every localized gingival growth should be included in the treatment planning to differentiate with other commonly found lesions

Cisto odontogênico calcificante: relato de caso / Calcifying Odontogenic Cyst: Case Report

Introdução: O Cisto Odontogênico Calcificante (COC), também conhecido como Cisto de Gorlin, é uma lesão odontogênica rara, descrita como neoplasia cística benigna, de origem odontogênica. Tem aspecto clínico variável e manifesta-se como lesão cística, não neoplásica, assintomática, de crescimento lento, podendo ser localmente agressivo. Não há predileção por gênero; ocorre normalmente na 2ª e na 3ª década de vida, sendo mais comum em regiões anteriores, podendo acontecer tanto na maxila quanto na mandíbula. O presente trabalho tem como objetivo o relato de um caso envolvendo uma paciente atendida na Clínica de Estomatologia da Faculdade de Odontologia da Universidade de São Paulo. Relato de caso: A paciente apresenta um COC em região anterior de maxila, caracterizado pelo aumento de volume da área paranasal à direita, sem característica dolorosa à palpação. Ao exame radiográfico, denota-se uma imagem radiolúcida, apresentando reabsorção radicular e imagens radiopacas sugestivas de calcificação interna. Considerações Finais: O tratamento realizado foi a enucleação e curetagem da loja óssea... (AU)

Introduction: The Calcifying Odontogenic Cyst (COC), also known as Gorlin cyst is a rare odontogenic lesion, described as benign cystic neoplasm of odontogenic origin. It has variable clinical appearance and manifests as a cystic lesion, non-neoplastic, asymptomatic, slow growing and may be locally aggressive. It has no gender predilection, usually occurs in the second and third decades of life, and it is more common in the anterior regions, may occur either in the maxilla or in the jaw. This study aims to report a case involving a patient treated at the Stomatology Clinic of University of São Paulo, Dentistry School. Case report: The patient has a COC in the anterior maxilla, characterized by the swelling of the paranasal area to the right without painful characteristic to palpation. On the radiographic exam is denoted a radiolucent image, showing radicular resorption and radiopaque suggestive images of internal calcification. Final considerations: The treatment provided was enucleation and curettage of bone cavity... (AU)

Cisto odontogênico calcificante na maxila posterior: um relato de caso atípico com acompanhamento de dois anos / Calcifying odontogenic cyst in the posterior maxilla: an atypical case report with two-year follow-up

Introdução: o Cisto Odontogênico Calcificante (COC) é um cisto odontogênico raro e indolor, que causa destruição óssea medular e expansão óssea cortical, sendo relatado pela primeira vez por Gorlin, em 1962. Objetivo: neste artigo relatamos um caso de COC na região mais rara de sua aparição, que é a região posterior da maxila em um jovem de apenas 15 anos. Relato de Caso: o paciente foi internado com um inchaço extra-oral, que cresceu lentamente durante os 8 meses anteriores; na cavidade bucal, também foi observado edema na região dos dentes 26, 27 e 28 e também acentuada mobilidade; radiograficamente, havia área radiolúcida unilocular com algumas áreas radiopacas (como uma casca alaranjada). Os achados histológicos observados incluem proliferação de células fantasmas e células basais colunares, semelhantes a ameloblastos e células com camadas superficiais frouxas. Conclusão: o paciente foi submetido à enucleação com curetagem de cisto como tratamento; devido a altas taxas de recorrência, o paciente teve um acompanhamento a cada três meses por um período de 2 anos, sem sinais de recidiva.

Introduction: Calcifying Odontogenic Cyst (COC) is an uncommon and painless odontogenic cyst, that causes bone marrow destruction and cortical bone expansion. It was first reported by Gorlin, in 1962. Objective: in this article, we report a case of COC in the rarest region of its appearance, which is the posterior region of the maxilla in a young man who is only 15 years old. Case Report: the patient was admitted with an extraoral swelling that grew slowly during the previous 8 months; in the oral cavity, edema was also observed in the region of the teeth 26, 27 and 28, and also marked mobility; radiographically, there was unilocular radiolucent area with some radiopaque areas (like an orange skin). The histological findings observed include proliferation of phantom cells, and columnar basal cells, similar to Ameloblasts and cells with loose superficial layers. Conclusion: the patient underwent enucleation with cyst curettage as a treatment; due to high rates of recurrence the patient had a follow up every three months for a period of 2 years without signs of relapse.

Quiste odontogénico calcificante de amplia dimensión: Reporte de caso con 8 meses de acompañamiento / Large calcifying odontogenic cyst: Case report with 8 months of follow-up / Cisto odontogênico calcificante de ampla dimensão: relato de caso com 8 meses de seguimento

El Quiste Odontogénico Calcificante (QOC) es una patología poco común que afecta en iguales proporciones a ambos se-xos, sin clara predilección por maxilar o mandíbula, es frecuentemente visto en asociación con dientes incluidos, así como otras patologías con las que puede compartir ciertas características especialmente radiológicas. El presente caso trata del manejo de un paciente masculino de 16 años de edad atendido en la clínica de cirugía oral y maxilofacial de la Universidad Nacional Autónoma de México, asintomático, con una lesión en mandíbula de importantes dimensiones, radiográficamente presentó una lesión radiolúcida de aproximadamente 4 cm, bordes definidos, abarca desde distal del 2do molar hasta el án-gulo y parte de la rama mandibular del lado izquierdo. Requirió un abordaje amplio que permita el tratamiento de la lesión y la prevención de una fractura asociada, así como un tratamiento que permita cubrir la posibilidad de una probable lesión tipo ameloblastoma más agresiva que el diagnóstico histopatológico no descartaba por completo. El paciente a 8 meses de seguimiento ha presentado una favorable evolución sin datos clínicos o radiográficos de recidiva, con adecuada función y estética.

Calcifying Odontogenic Cyst (COC) is a rare pathology that affects both sexes in equal proportions, without clear prefer-ence for maxilla or mandible. It is frequently seen in association with teeth included, as well as shares certain particularly radiological features with other diseases. The present case deals with the management of a 16-year-old male patient treated at the oral and maxillofacial surgery clinic of the Universidad Nacional Autónoma de Mexico, asymptomatic, with a jaw in-jury of important dimensions, radiographically presented a radiolucent lesion of approximately 4 cm, defined edges, covers from distal of the 2nd molar to the angle and part of the mandibular branch on the left side. It required a wide approach that allows the treatment of the lesion while simultaneously preventing an associated pathologic fracture. The treatment should also cover the possibility of a more aggressive ameloblastoma type lesion than the histopathological diagnosis did not rule out completely. The patient at 8 months of follow-up had a favorable evolution without clinical or radiographic evidence of recurrence, with adequate function and aesthetics.

O Cisto Odontogênico Calcificante (COC) é uma patologia rara que afeta em proporções iguais para ambos os sexos, sem clara preferência para a maxila ou mandíbula é muitas vezes visto em associação com dentes incluídos, e outras patologias que podem compartilhar certas características especialmente radiológicas. O presente relato de caso diz é ao respeito à gestão de um paciente homem de 16 anos de idade tratado na clínica de cirurgia oral e maxilo-facial da Universidade Au-tônoma do México, assintomático, com uma lesão na mandíbula de dimensões importantes, radiografia mostrou uma lesão radiolúcida de aproximadamente 4 cm, bordas definidas, afetando desde o distal do 2º molar até o ângulo e parte do ramo mandibular do lado esquerdo. Foi necessária uma ampla abordagem que permita o tratamento da lesão e prevenção de uma fratura associada, além disso um tratamento que irá abranger a possibilidade de lesão provavelmente tipo ameloblastoma mais agressivo que o diagnóstico histopatológico não descartou completamente. O paciente aos 8 meses de seguimento teve uma evolução favorável sem dados clínicos ou radiográficos de recorrência, com função e estética adequadas.

Calcifying Odontogenic Cyst of Mandible: A Case Report

The term calcifying odontogenic cyst was first introduced by Gorlin in 1962. It represents 2% of all odontogenic pathological changes in the jaw. The calcifying odontogenic cyst usually arises intraosseously, but it may also occur extraosseously, with about equal frequency in the mandible and maxilla (1:1). The age of the patients may range from 5 to 92 years, with peak incidence in the second and sixth decade of life. Radiographically, the lesion appears as a unilocular or multilocular well-defined radiolucency that may contain small irregular calcified bodies of varying sizes, and it may be associated with an odontome or an unerupted tooth. We present a case report of 17year-old female with Calcifying odontogenic cyst involving right body and angle of mandible.

Perfil clínico e histopatológico do cisto odontogênico calcificante: relato de caso / Clinical and histopathological features of calcifying odontogenic cyst: case report

O cisto odontogênico calcificante (COC) é considerado como condição patológica benigna de ocorrência rara em maxila e mandíbula, caracterizado por revestimento cístico de células epiteliais odontogênicas, contendo células fantasmas com propensão a regiões de calcificação. Neste artigo, descreveu-se a configuração clínica e histopatológica do COC por meio de relato de caso submetido a tratamento cirúrgico e acompanhamento pós-operatório. Paciente de 11 anos apresentou aumento de volume em região maxilar à esquerda, próxima ao sulco nasolabial e sem sintomatologia dolorosa. Os exames radiográficos indicaram lesão radiolúcida, bem circunscrita e expansiva em maxila, que foi submetida a enucleação associada a ostectomia marginal das paredes corticais ósseas. O histopatológico revelou revestimento cístico com epitélio odontogênico ameloblástico, ninhos espalhados de células fantasmas e regiões eosinofílicas de material compatível com dentinóide. Evidenciou-se, assim, perfil clínico de COC, que pode ser confundido com outras lesões císticas ou tumorais, sendo essencial o diagnóstico por meio de análise histopatológica. A abordagem cirúrgica proporcionou adequado diagnóstico e tratamento. Após acompanhamento clínico e radiográfico, não houve recorrência do COC.

Calcifying odontogenic Cyst (COC) has been considering as benign pathological ill and rare occurrence in maxilla and mandible, there been showed odontogenic epithelial cystic lining demonstrating ghost cells with a propensity to calcify. In this article, we described the clinical and histopathological features from case reported who had undergone surgical approach and postoperative follow-up. A 11 year-old-girl had presented volumetric increased in left maxilla area near nasolabial fold. The radiography images had indicated radiolucent lesion, well-circumscribed and wide on cortical maxillary bone, which was undergone enucleation associated with marginal osteotomy on the bone cortical walls. The histopathological features showed cystic lining with odontogenic epithelium containing ghost cells and some areas with eosinophilic matrix material compatible dentinoid. Thus, it was evidenced a clinical features of COC which could be confused with other cystic or tumoral lesions, there being essential on diagnosis and treatment. After clinical and radiographic follow-up during 07 years, there was no recurrence of the COC.

Ghost cell odontogenic carcinoma on right mandible and its respective surgical reconstruction: a case report

Calcifying cystic odontogenic tumor (CCOT) is defined as an odontogenic cyst-like benign neoplasm that characteristically contains several ghost cells, ameloblastoma-like epithelium, and occasional calcification. Ghost cell odontogenic carcinoma (GCOC), a malignant form of CCOT, is an exceptionally rare malignant tumor. In this report, we present a case of a 53-year-old man whose chief complaint was a solitary mass on the right mandible area. The mass was completely removed through an extraoral surgical approach and reconstructive surgery was performed in two phases.

Conservative approach to recurrent calcifying cystic odontogenic tumor occupying the maxillary sinus: a case report

Calcifying cystic odontogenic tumor (CCOT) is an uncommon benign cystic neoplasm of the jaw that develops from the odontogenic epithelium. Invasion into the maxillary sinus by a CCOT is not a typical, and the recurrence of the cystic variant of CCOT in the posterior maxilla is rare. This report describes a recurrent CCOT occupying most of the maxillary sinus of a 24-year-old male patient. As a treatment, marsupialization was carried out as a means of decompression, and the involved teeth were all endodontically treated. Afterward, surgical enucleation was performed. The size of the lesion continued to shrink after marsupialization, and the maxillary sinus restored its volume. This patient has been followed-up for 3 years after the surgery, and there have not been any signs of recurrence.

Central Calcifying Cystic Odontogenic Tumor of Mandible - A Case Report.

The calcifying cystic odontogenic tumor (CCOT) is a rare benign odontogenic cystic neoplasm. The terminological conundrum regarding its categorization as a cyst or a tumor has been resolved after the latest WHO classification (2005) that has labelled it as a tumor. The diversity in its morphological patterns, clinical behaviour, histologic complexity and prognosis has led to the practise of multiple management strategies with variable results. This report describes a case of CCOT presenting as a large cystic lesion in theanterior mandible that was managed by enucleation and curettage with a postoperative one year recurrence free follow up. A brief review of literature pertaining to various management strategies of CCOT in comparison with dentinogenic ghost cell tumor (DGCT) is also presented.

Tumor Odontogênico Cístico Calcificante associado a Odontoma / Tumor quístico odontogénico calcificante asociado con odontoma / Calcifying cystic odontogenic tumour associated with Odontoma

O Tumor Odontogênico Cístico Calcificante ou Cisto de Gorlin é uma lesão odontogênica rara, descrita como neoplasia cística benigna de origem odontogênica, que apresenta comportamento clínico variável. Sua patogênese permanece desconhecida, embora comumente seja aceito que se desenvolva a partir de remanescentes do epitélio odontogênico, presentes na da mandíbula, maxila e gengiva. O Objetivo deste artigo é relatar o caso clínico de tumor quístico odontogénico calcificante asociado com odontoma. Paciente do gênero masculino, 11 anos de idade, que procurou o Serviço de Cirurgia e Traumatologia Bucomaxilofacial do Hospital Santo Antônio-OSID/Salvador-BA, apresentando aumento de volume intrabucal indolor, na região de corpo mandibular esquerdo. No exame imaginológico observou-se lesão radiolúcida unilocular, bem delimitada, estendendo-se da região de incisivo lateral até primeiro pré-molar inferior esquerdo, associado à massa radiopaca em seu interior além de unidade supranumerária deslocada para basilar da mandíbula. Foi realizada a biópsia excisional da lesão, constatando-se o diagnóstico de tumor odontogênico cístico calcificante associado à odontoma. O paciente encontra-se sem sinais de recidiva, com dois anos de acompanhamento em tratamento ortodôntico. O conhecimento das características da lesão, um exame clínico detalhado e a solicitação de exames complementares são fundamentais para um diagnóstico criterioso, com a finalidade de oferecer ao paciente o tratamento mais adequado, que atualmente consiste na enucleação total da lesão, obtendo-se um bom prognóstico, raramente com relatos de recidiva(AU)

El tumor odontogénico quístico calcificante es una lesión rara, descrito como neoplasia benigna, de origen odontogénico, que presenta un comportamiento clínico variable. El objetivo de este trabajo es presentar el caso clínico de tumor odontogénico quístico calcificante associado a odontoma. Paciente varón, de 11 años de edad, quien trató de Servicio y Cirugía Máxilofacial, Hospital Santo Antônio-OSID/Salvador-BA, y presentó hinchazón sin dolor intraoral en la región del cuerpo mandibular. En el examen de imágenes revelaron una lesión radiolúcida unilocular, bien definida, que se extiende desde la región del incisivo lateral al primer premolar inferior izquierdo, asociado con una masa radiopaca dentro de la unidad más supernumerario desplazado basilar mandibular. Se realizó biopsia por escisión de la lesión, lo que confirma el diagnóstico de tumor quístico calcificante asociado con odontoma odontogénico. El paciente se encuentra sin signos de recurrencia, con 2 años de seguimiento, el tratamiento ortodóncico. El conocimiento de las características del tumor odontogénico quístico calcificante, el examen clínico detallado y la solicitud de exámenes complementarios constituyen el fundamento para el diagnóstico certero con la finalidad de ofrecer al paciente el tratamiento más adecuado, que actualmente consiste en la enucleación total de la lesión, obteniéndose un buen pronóstico, con raras recidivas(AU)

The calcifying cystic odontogenic tumor is a rare lesion, described as benign neoplasm of odontogenic origin, which has variable clinical behavior. The aim of this paper is to present a case of calcifying cystic odontogenic tumor associate to odontoma. This is an 11 year male patient, who was treated at Maxillofacial Surgery Service, Hospital Santo Antônio-OSID/Salvador-BA and who presented intraoral swelling with no pain in the mandibular body region. The imaging examination revealed a well-defined unilocular radiolucent lesion, which extended from the lateral region of the lower left first premolar to the incisor, associated with a radiopaque mass within the unit, displaced supernumerary mandibular basilar. Excisional biopsy of the lesion was performed, and it confirmed the diagnosis of cystic odontogenic tumor associated with odontoma calcifying. At present, the patient is with no signs of recurrence during this two year follow-up orthodontic treatment. Knowledge of the calcifying cystic odontogenic tumor characteristics, detailed clinical examination and additional tests are the basis for accurate diagnosis in order to offer patients the most appropriate treatment, which currently consists of total enucleation of the lesion achieving good prognosis, and rare recurrence(AU)

Dentinogenic Ghost Cell Tumor: A Case Report and Review of Literature

Tumor odontogênico cístico calcificante com proliferação ameloblastomosa em seio maxilar / Calcifying cystic odontogenic tumor with ameloblastoma proliferation in the maxillary sinus

O tumor odontogênico cístico calcificante (TOCC) com proliferação ameloblastomosa é uma variante rara entre os cistos maxilares. Este trabalho objetiva apresentar o relato clínico de um paciente do sexo masculino, 18 anos de idade, que apresentava aumento de volume extra e intraoral do lado esquerdo da maxila, firme à palpação, de característica normocrômica e indolor. A conduta consistiu em realização de tomografia Cone Beam, biópsia incisional, remoção completa da lesão, curetagem e fixação maxilar. O paciente encontra-se em acompanhamento clínico e radiográfico sem recidiva após doze meses. Dessa forma, ressalta-se a importância do diagnóstico precoce, a conduta clínica empregada e o acompanhamento periódico.

Calcifying cystic odontogenic tumors (CCOT) with proliferative ameloblastoma are a rare variant among maxillary cysts. This study aims to present a clinical report of an 18-year-old male patient with extra and intra oral swelling of the left maxilla, firm to touch, with normochromic characteristics and painless. The clinical approach comprised cone-beam tomography, incisional biopsy, complete removal of the lesion, curettage and maxilla fixation. His clinical and radiographic follow-up has revealed no relapse after 12 months. Hence, this study corroborates the importance of early diagnosis, clinical approach and periodical follow-ups.

Multicystic Variant of Calcifying Cystic Odontogenic Tumor Associated With Odontome - Report of A Case And Review.

Calcifying cystic odontogenic tumor is an uncommon odontogenic neoplasm which is included in the heterogenous group of lesions under a broader description of Ghost cell odontogenic tumors. All these lesions have the presence of ghost cells as a common feature. Calcifying cystic odontogenic tumor is a unique lesion with variable biologic behaviour and found to occur with other odontogenic tumours. We present a case of Calcifying cystic odontogenic tumor occurring in a 15 year old boy involving an unerupted permanent canine and premolar. The tumor was multicystic in nature and was associated with a complex odontome. This article also includes an update on nomenclature and classification of ghost cell odontogenic lesions.

Removal of Odontogenic Keratinocyst using Versatile Maxillary Window in BCNS

PURPOSE: Basal cell nevus syndrome (BCNS), also known as Gorlin syndrome, is a rare autosomal dominant disorder. It is characterized by complex neoplastic syndrome with multisystemic manifestations, involving six major features. This article presents a rare genetic disorder and usage of the author's methods for odontogenic keratocyst, developed in the maxillary sinus. METHODS: A 67-year-old man was presented with large calcified maxillary mass and multisystemic manifestations and findings that matched with basal cell nevus syndrome. The calcified maxillary mass was removed via the versatile maxillary window and maxillary bone segment was repositioned. RESULTS: Histopathologic findings revealed that maxillary and mandibular lesions were odontogenic keratocysts and the skin lesions were basal cell carcinoma. CONCLUSION: Basal cell nevus syndrome is a rare genetic disease that requires surveillance and care for basal cell carcinoma and multisystemic problems. The author's method was satisfactory for maxillary odontogenic keratocyst in the aspect of the approach and reconstruction.

Calcifying Odontogenic Cyst Associated with Maxillary Sinus: Case Report

Calcifying odontogenic cyst: a case report

The calcifying odontogenic cyst(COC) is considered to occupy a position between a cyst and an odontogenic tumor-having charateristics of both. Gorlin and col. described the COC for first time as an own pathological entity in 1962. Clinically, the COC represents 1% of the odontogenic lesion. It is possible to be found from the first decade to the eight decade but is more frequent during the second decade. It affects in same proportion the maxilla and jaw, being the most in tooth-bearing area of the jaw. This case of COC associated with an unerupted tooth which appeared in the right mandible of 22-year-old woman, was reported. This case report is to present a review of the literature relates to this case of COC and its treatment, discuss clinical, radiographic, histological and therapeutic aspects.

Odontogenic ghost cell carcinoma arising from odontogenic epithelial tumor in maxilla: A case report

The neoplastic variant of calcifying odontogenic cyst has various designation, and its malignant counterpart has been reported as aggressive epithelial ghost cell tumor or odontogenic ghost cell carcinoma. Odontogenic ghost cell carcinoma(OGCC) is a rare carcinoma first documented in 1985. It is composed of varying sized islands of anucleated cells with homogenous, pale eosinophilic cytoplasm, so called ghost cells, were admixed with nucleated cells. We report a case of maxillary OGCC developed from odontogenic epithelial tumor in a 25-year-old man with literature review.