Cellular changes in cancer following isolation perfusion using nitrogen mustard

Isolation perfusion with the use of chemotherapeutic agents is an added modality of treatment in our fight against malignancy. It is, however, limited to cancer patients who fail to respond to conventional type of treatment (surgery and irradiation). Its therapeutic value is best demonstrated in regionally recurrent or inoperable cancer where it affords significant relief of pain to a lesser extent, a diminution in the size of the tumor mass. (Conclusion)