ABSTRACT
Objective To describe the incidence trend of leukemia in Shenzhen during 2001 to 2015, and to provide base data for designing prevention and treatment strategies on leukemia. Methods The leuke-mia incidence data and population data collected by Shenzhen Cancer Registry from 2001 to 2015 were used in our analysis. The crude incidence,age-standardized incidence rate by Chinese standard population (ASR China)and age-standardized incidence rate by world standard population (ASR world)were calculated. The annual percentage change (APC)of the incidence was analyzed by Joinpoint regression. Results Shenzhen Cancer Registry registered 2106 new cases of leukemia from 2001 to 2015. The crude incidence was 6. 31 per 100000,with 6. 75 per 100000 ASR China and 7. 15 per 100000 ASR world. Cumulative rate (0-74 years) was 0. 63％,and truncated rate (35-64 years)was 7. 03 per 100000. From the perspective of gender distribu-tion,the incidence of male was significantly higher than female,with a sex ratio of 1. 38 : 1. In terms of time trend,the incidence of leukemia was stable,and the Joinpoint regression showed that APC = - 0. 09％(95％ CI:- 1. 60％ -1. 41％,P = 0. 92). In terms of subtypes,acute myelocytic leukemia (AML)accounted for 17. 66％ of the total cases,and the incidence of AML has increased during 2001 to 2015 (APC = 13. 34％, 95％ CI:5. 71％ -21. 51％,P < 0. 01). The median age of leukemia patients was 36 years old,and the mean age was 37. 29 years old. The two peaks of the incidence were 1-4 and 80-84 age groups,and the ASR inci-dences were 9. 13 per 100000 and 39. 40 per 100000 respectively. Conclusion The incidence of leukemia is very high in Shenzhen. Children and the elderly are at high risk of leukemia. Government needs to guide insti-tutions to carry out research to reduce the incidence of leukemia.
ABSTRACT
Objective To investigate the bladder cancer incidence and mortality in cancer registries of Zhejiang province during 2000 to 2009.Methods The data were collected from six cancer registries in Zhejiang province.Staff of Zhejiang Provincial Cancer Prevention and Control Office checked the data and calculated crude rate,standardized rate and trend. Results The incidence rate of bladder cancer in Zhejiang cancer registration areas was 6.97 /105 during 2000 to 2009. The incidence of male was higher than female,the ratio was 3.40∶1.The incidence rate increased from 2000(6.36 /105 ) to 2009(7.99 /105 ),with the Annual Percent Change (APC)of 3.69% (95% Confidence Interval:2.49% ~4.90%). The mortality rate of bladder cancer in Zhejiang cancer registration areas was 2.00 /105 during 2000 to 2009.The mortality of male was higher than female,with the ratio 3.27∶1.The mortality of bladder cancer showed ascending trend with a slight fluctuation from 2000 to 2009 (APC =2.28%).The incidence and mortality of bladder cancer showed significantly increasing in above 55 years old age groups.The incidence rate peaked in the 80 -84 age group,while the mortality peaked at age group of over 85 years old.Conclusion The bladder cancer prevention and control work should be focused on the elderly male population in Zhejiang province.