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Journal of the Korean Ophthalmological Society ; : 207-213, 1990.
Article in Korean | WPRIM | ID: wpr-91802

ABSTRACT

The effect of Carteolol hydrocholride on the Na-K ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiments were also designed to determine the action of Carteolol hydrochloride on the Na-K ATPase activity in anterior capsule and epithelium of cattle lens. The following results were observed. 1. The predominent location of Na-K ATPase was located in the epithelim and NaK ATPase was closely related with active trasport system of sodium and potassium in the lens epithelium. 2. The activity of Na-K ATPase of cattle lens epithelium was alomst totally inhibited by Ouabain. 3. Beta-adrenergic blocking agent(Carteolol hydrochloride) in the epithelium of cattle lens was shown to be actively transported by the ATPase. 4. The Na-K ATPase activity of cattle lens epithelium was inhibited by Carteolol hydrochloride.


Subject(s)
Animals , Cattle , Adenosine Triphosphatases , Biological Transport, Active , Carteolol , Epithelial Cells , Epithelium , Membranes , Ouabain , Potassium , Sodium
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