ABSTRACT
El Neurotecoma Celular es un raro tumor benigno de histopatogénesis incierta extremadamente atípico. Clínicamente la lesión es poco característica, generalmente es un nódulo solitario asintomático de crecimiento lento que se puede presentar en piel y mucosas. El diagnóstico se basa en los hallazgos histológicos y de inmunohistoquímica, se considera que los neurotecomas en sus distintas variantes: mixoide, celular o mixta forman parte de un espectro de tumores con un supuesto origen en la vaina nerviosa, sin embargo numerosos autores afirman que se trata de tumores diferentes que justifican una clasificación separada. A nivel mundial existen tan solo alrededor de 300 reportes de este tipo de tumoración, por ello el interés de presentar el caso de un paciente masculino de 13 años de edad quien ingreso y fue tratado por el servicio de cirugía plástica y reconstructiva del hospital universitario de los andes y quien curso con una neoformación de aproximadamente 30mm de diámetro, firme, de crecimiento lento, localizada en la porción del margen derecho de la lengua con 14 meses de evolución. El diagnóstico histopatológico confirmó un Neurotecoma Celular(AU)
The Cell Neurothekeoma is a rare benign tumor of uncertain histopatogenesis extremely atypical. Clinicallyncharacteristic lesion, usually an asymptomatic solitary nodule of slow growth. It can occur in the skin and mucous membranes. The diagnosis is based on histological and immunohistochemically findings, the neurotecomas are considered that in its different considered that in its different variants: myxoid, mixed cell or mixed, are a part of putative origin tumors in the nerve sheath, however many authors claim that this are different tumors that justify a separate classification. Worldwide there are only about 300 reports of this type of tumor so the interest of presenting the case of a male patient of 13 years old who income and was treated by the service of plastic and reconstructive surgery at the Andes University Hospital and he coursed with a new formation of approximately 30mm diameter, firm, slow-growing, located in the right lateral portion of the tongue with 14 months duration. Histopathological diagnosis confirmed a Cell Neurothekeoma(AU)
Subject(s)
Humans , Male , Adolescent , Mouth Neoplasms , Tongue Neoplasms , Neurothekeoma/pathology , Surgery, Oral , Medical OncologyABSTRACT
Cellular neurothekeoma is a rare, benign, cutaneous neoplasm of uncertain histogenesis and usually presents as a solitary papule or nodule on the head or neck area of children and young adults. Cellular neurothekeoma was thought to represent a cellular variant of nerve sheath myxoma but this neoplasm is histologically different from nerve sheath myxoma. Cellular neurothekeoma is characterized by a fasciculated, somewhat well-circumscribed proliferation of epithelioid and spindle cells. Herein, we report a case of cellular neurothekeoma with a review of related literature.
Subject(s)
Child , Humans , Young Adult , Head , Neck , NeurothekeomaABSTRACT
Nerve sheath myxoma(NSM) is a rare cutaneous neoplasm of uncertain histogenesis. NSM can be divided into two groups; NSM1 (a myxoid NSM) and NSM2 (a cellular neurothekeoma). NSMs are characterized histologically by well-defined, lobular or plexiform dermal proliferation of stellate, spindle-shaped cells embedded in abundant myxoid stroma. A variable amount of nerve fascicles are entrapped within and around the tumor. Two variants of NSM share the same features to a certain degree but differ in cellularity and mucin deposition. We report two cases of NSMs with different clinical and histopathologic features.