Lesión central de células gigantes en mandíbula: reporte de un caso y revisión de la literatura / Central giant cell lesion in the mandible: report of a case and review of the literature

El término lesión central de células gigantes describe un grupo de lesiones no odontogénicas intraóseas benignas que histológicamente presentan células gigantes. En los maxilares diversas entidades pueden compartir esta característica histológica como hiperparatiroidismo, querubismo y el granuloma central de células. Se clasifi ca en agresiva y no agresiva, dependiendo de las características clínicas, imagenológicas e histopatológicas. El tratamiento para las LCCG es la escisión quirúrgica donde la extensión puede variar desde curetaje simple hasta resecciones en bloque, también se ha reportado el uso de curetaje combinado con crioterapia, o bien ostectomía periférica. Las tasas de recurrencia posterior al tratamiento quirúrgico varían entre 11 al 49%; sin embargo, en lesiones agresivas se han reportado tasas de hasta 72%. Se reporta un paciente de 40 años con una lesión central de células gigantes con comportamiento agresivo que se trató con resección quirúrgica y respondió favorablemente al tratamiento (AU)

The term central giant cell lesion describes a group of non-odontogenic benign intraosseous tumors that histologically contain giant cells. Various entities in the jaws may share this histological feature including hyperparathyroidism, cherubism, and central giant cell granuloma. It can be classifi ed as: aggressive and non-aggressive, based on clinical and radiographic characteristics. Traditional treatment has been surgical excision, the extension of which can vary from simple curettage to block resections, the use of curettage combined with cryotherapy or peripheral ostectomy has also been reported. Recurrence rates after surgical treatment range from 11 to 49%; however, in aggressive lesions, rates of up to 72% have been reported. We present a case of a patient with a central giant cell lesion with aggressive behavior was treated with surgical resection with a favorable outcome (AU)

Non-aggressive central giant cell granuloma in Mandible- A case report.

Central giant cell granuloma is an uncommon benign proliferative lesion accounting for less than 7% of all benign jaw lesions of unknown etiology, and known to occur in anterior mandible in the first three decades of life with female predilection. Clinical, radiological and histopathological parameters describes Aggressive and Non aggressive lesion with features of high recurrence in the aggressive forms which are found in younger age group. This case report presents a 16 year old female with classical features of non aggressive central giant cell granuloma crossing mid line in the mandible which is extending posteriorly.