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Objective To investigate the effect of cerebrospinal lfuid replacement combined with vancomycin and dexamethasone intrathecal therapy on biochemical indicators of postoperative intracranial infection, in order to improve the clinical diagnosis and treatment. Methods 70 cases with intracranial infection collected in Third Hospital of Beijing Armed Police Corps from February 2010 to April 2013 were as subject, and randomly divided into two groups. Control group(n=35) were given cerebrospinal lfuid replacement and ceftriaxone intravenously, observation group(n=35) were given cerebrospinal lfuid replacement combined with vancomycin and dexamethasone intrathecal injection. The clinical effects and biochemical indicators were observed after treatment in two groups. Results In control group, the cure rate was 22.86%and total efifciency was 77.14%. In observation group, the cure rate was 37.14% and total efficiency was 91.43%. The differences between two groups were statistically significant (P<0.05). The differences of leukocytes, glucose, protein, intracranial pressure in two groups after treatment were also statistically signiifcant(P<0.05). Conclusion Cerebrospinal lfuid replacement combined with vancomycin and dexamethasone intrathecal injection therapy can increase intracranial infection.
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Objective To explore clinical effects of transcatheter aneurysm embolization and cerebrospinal fluid replacement therapy for the treatment of subarachnoid hemorrhage .Methods Clinical path data of 85 cases of subarachnoid hemorrhage patients from January 2010 to August 2012 were analyzed ,and all were used transcatheter aneurysm embolization and cerebrospinal fluid re-placement therapy to observe the clinical effects .Results A total of 85 patients with 84 cases were cured or improved(98 .82% ) , died in 1 case(1 .18% ) and occur complications in 10 cases(11 .76% ) .68 cases of those were followed up for 0 .5-2 .0 years and no case occurred rebleeding .85 patients were hospitalized for 10 to 40 days ,and the average hospital stay was(17 .5 ± 13 .0)d .Conclu-sion Transcatheter aneurysm embolization is a safe ,effective method treating subarachnoid hemorrhage ,combined with cerebrospi-nal fluid replacement therapy to shorten the course ,reduce complications and improve the cure rate .
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Objective To evaluate the clinical value of combined treatment for spontaneous intraventricular hemorrhage. Methods 26 patients with spontaneous intraventricular hemorrhage were conducted on the whole turn of low lateral drainage of bilateral urokinase infusion therapy, supplemented by lumbar puncture cerebrospinal fluid replacement. Results The total effective rate was 84.62% ,mortality rate was 15. 38%. Conclusion Bilateral lateral drainage of alternating low urokinase infusion,supplemented by lumbar puncture cerebrospinal fluid replacement was effective in treatment of spontaneous intraventricular hemorrhage. It could reduce mortality in patients with intraventricular hemorrhage and increase the patients' prognosis.
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Objectives To investigate the effect of cerebrespinal fluid replacement using three- way pipe on subarachnoid hemorrhage and the nursing points were summarized. Methods 80 subarachnoid hemorrthage patients were divided into the treatment group and the control group with 40 patients in each group. The control group received traditional medical treatment and routine nursing. The treatment group received cerebrospinal fluid replacement.The incidence of complication,death and clinical effect were com-pared between the two groups and the data under χ2 test and t test. Results Each index in the treatment group was better than that of the control group. Conclusions Intensified nursing after cerebrospinal fluid replacement can improve treatment effect, alleviate prognosis and supply reference for future nursing work for this disease.
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Objective To explore the therapeutic effect of cerebrospinal fluid (CSF) replacement combined with intrathecal injection on tuberculous meningitis. Methods Fifty-five patients with tuberculous meningitis were randomly divided into treatment group and control group. The patients in the treatment group were treated with CSF replacement combined with intrathecal injection on the basis of routine anti-tuberculosis therapy. The curative effects between these two groups were analyzed after 8 weeks. Results The total effective rate was 95.7% in the treatment group,compared with that 61.9% in the control group (P < 0.01); the healing rate in the treatment group was 56.2% vs 28.6% in the control group. In addition,the decay rate for WBC and CSF pressure in the treatment group are more rapid than those in the control group(P < 0.05). Conclusion CSF replacement combined with intrathecal injection has better curative effect in patients with tuberculous meningitis.
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Objective To study the curative effect of cerebrospinal fluid replacement combining intravenous drips and intrathecal injection of amphotericin B in the treatment of cryptococcal neoformans meningitis(CNM for short).Methods 28 CNM patients were randomly divided into two groups.Group A was the treatment group,and the treatment method was cerebrospinal fluid replacement combining intravenous drips and intrathecal injection of amphotericin B.Group B was the control group,and the treatment method was only intravenous drips and intrathecal injection of arnphotericin B.The period of treatment was 16 weeks.The curative effect was assessed in terms of symptoms,physical features,CSF routine examination,CSF cultivation and smear examination.Results The cura- tive effect of treatment group was better than that of the control group.There were remarkable differences between these two groups(P
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@#ObjectiveTo explore pathogenesis of headache after subarachnoid hemorrhage (SAH) whether related with immune inflammatory reaction in subarachnoid and observe the effect of immunosuppressive action of dexamethasone on headache.Methods80 patients who was consciousness and complained headache after SAH were randomly divided into four groups, treated only with mannitol, mannitol plus cerebrospinal fluid (CSF) replacement, intrathecal and vein injection with dexamethasone. Effects of four groups were observed.ResultsEfficiencies of four groups were respectively the mannitol group 27.27%, the permutation group 66.67%, the intrathecal group 92.36% and the vein group 30.00%. There was a significantly difference between the intrathecal group and other three groups, and the time of headache remission for intrathecal group was also longer than that of other three groups (P<0.01).ConclusionThe wide immune inflammatory responses in subarachnoid induced by degenerative and hemic CSF is likely main cause of headache after SAH and intrathecal injection with dexamethasone has an obviously effect.