ABSTRACT
Chinese materia medica (CMM) processing is a traditional Chinese pharmaceutical technology with independent intellectual property rights in China, which includes historical evolution, processing technology, quality standards and processing mechanism. Clarification of the chemical constituents changes in seed Chinese materia medica (SCMM) is the core purpose of mechanism research of CMM processing. It is well known that "SCMM be stir-heated before using", which has been confirmed by many research institutions at home and abroad. This article gives a brief introduction to the chemical mechanism during SCMM processing and concludes their similarities. It has been found that the chemical constituents in SCMM have experienced complex changes both in quantitative and qualitative during processing. The main chemical reactions occurred in the SCMM processing are decomposition reaction so as to increase therapeutic effect or reduce toxicity and so on. The theory has a certain scientific connotation and it should be clarified under the guidance of the theory of traditional Chinese medicine for rational clinical use.