ABSTRACT
By analyzing the problems such as the non-standard phenomenon in the implementation and operation of the current chief review system, the unclear responsibility of the chief review committee, and the lack of sound safeguard measures in the implementation of the chief review system, this paper put forward some suggestions, such as establishing and perfecting the chief review system of the ethics committee, clearly specifying the responsibilities and rights of the chief review committee, comprehensively strengthening the safeguard work and other improvement measures for the implementation of the chief review system, so as to provide suggestions for the more standardized and efficient operation of the chief review system in ethics review in China.