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Rev. bras. hematol. hemoter ; 31(supl.2): 51-56, ago. 2009.
Article in English | LILACS | ID: lil-527524

ABSTRACT

Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in adults in the Western world and predominantly affects the elderly. Although CLL remains incurable with standard treatments, important progress in treatment, which classically is given only when the disease has become symptomatic, has been made in recent years. The diagnosis of CLL does not necessarily convey the necessity of treatment. However, treatment has classically been indicated in symptomatic or progressive disease according to criteria defined by stage of disease. Treatment of CLL has been markedly improved by highly effective new drugs and drug combinations.


A leucemia linfoide crônica (LLC) é a mais frequente leucemia dos adultos no mundo ocidental e acomete principalmente pacientes idosos. Embora esta doença continue incurável, progressos importantes no tratamento, habitualmente, apenas dado a pacientes sintomáticos, têm sido obtidos nas últimas décadas. O diagnóstico de LLC não obrigatoriamente exige terapia. Entretanto, tratamento tem sido classicamente indicado em pacientes sintomáticos ou com doença progressiva de acordo com os critérios definidos pelo NCI. A resposta terapêutica tem sido marcantemente melhor com novas drogas e combinações altamente eficientes. O autor faz aqui uma breve revisão do assunto.


Subject(s)
Leukemia, Lymphocytic, Chronic, B-Cell , Patients , Therapeutics , Aged , Leukemia, Lymphoid , Western World , Diagnosis , Drug Combinations , Drug Therapy , Rituximab
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