ABSTRACT
PURPOSE: To report a case of chondroid syringoma that involved the eyelid margin, was accompanied by cilia loss, and required differential diagnosis with other malignant eyelid masses. CASE SUMMARY: A 46-year-old woman presented with a recurrent mass in the right lower eyelid margin, which was observed 10 years earlier, where incision and curettage had already been performed twice. The mass was neither tender nor ulcerated, was brighter in color than the neighboring skin, and had a smooth surface with cilia loss. The pathologic findings obtained from an incisional biopsy were compatible with a dermoid cyst. Full-thickness excision of the eyelid mass and direct closure were subsequently performed. The pathologic diagnosis after excisional biopsy was chondroid syringoma because cystic structures in the chondroid stroma were observed.