ABSTRACT
BACKGROUND: The prevalence and clinical characteristics of dermatomycosis are not static but change under the influence of various forces such as geographic factor, social environment and development in prophylaxis and treatment. OBJECTIVE: To investigate the present status of dermatomycosis and changes on the prevalence, sex, age distribution and causative organisms. METHODS: We performed clinical and mycological studies on 7,785 cases of dermatomycosis among outpatients of Dermatologic clinic of Chonnam University Hospital for 10 years, from January 2001 to December 2010. RESULTS: The incidence of dermatomycosis was 12.5% of outpatients and show the highest incidence over 7th decades (24.2%). The incidence of tinea pedis (24.1%) was the highest, followed by onychomycosis (18.1%). Coexisting fungal infections were found 693 (9.2%) and the cases of tinea pedis with onychomycosis were the most common. The positive rate of KOH examination was 49.7% and the positive rate of culture on Sabouraud's dextrose agar media was 36.5%. Trichophyton rubrum was the most common causative organism of dermatomycosis (51.1%), followed by Candida species (33.2%). CONCLUSIONS: Consideration of the changes between current and past epidemiologic, clinical and mycological features in the cutaneous fungal infections are important to investigational efforts, diagnosis, and treatment.
Subject(s)
Humans , Agar , Age Distribution , Candida , Dermatomycoses , Geography , Glucose , Incidence , Onychomycosis , Outpatients , Prevalence , Social Environment , Tinea Pedis , TrichophytonABSTRACT
BACKGROUND: Superficial fungal infections are common dermatologic disorders, and causative organisms include dermatophytes, yeasts, and nondermatophyte molds. The data about incidence of fungal pathogens can be used to predict increase in antifungal resistasnce and the adequacy of our current pharmacologic repertoire, and provide insight into future developments. OBJECTIVES: This study aimed to identify epidemiologic features and the various organisms from clinically suspected cases of superficial fungal infection. METHODS: A total 11,656 specimens were collected from clinically suspected tinea corporis, tinea cruris, tinea capitis, tinea faciei, tinea manuum, tinea pedis, and finger and toe onychomycosis among patients of Dermatologic clinic of Asan Medical Center from 1998 through 2002. Clinical and culture studies on these cases were performed. However, attemps to establish the causative organism were not done. RESULTS: The incidence of clinically suspected cases was highest in the fifth to sixth decades. The ratio of male to female was 1.09:1. The incidence of toenail was highest, followed by feet, fingernail, trunk and extremeties, groin, scalp, and face. The positive rate of KOH examination was 49.2% and that of culture was 51.4%. Dermatophytes was the most commoly isolated fungal organisms except fingernail onychomycosis. Trichophyton rubrum was the most prevalent fungal pathogen among them. High incidence of Candida species and Trichosporon species was documented in hands, feet and nails. CONCLUSION: Consideration of the current epidemiologic, clinical and mycologic features in the cutaneous fungal infections is of key importance to investigational efforts, diagnosis, and treatment.
Subject(s)
Female , Humans , Male , Arthrodermataceae , Candida , Diagnosis , Fingers , Foot , Fungi , Groin , Hand , Incidence , Nails , Onychomycosis , Scalp , Tinea , Tinea Capitis , Tinea Pedis , Toes , Trichophyton , Trichosporon , YeastsABSTRACT
BACKGROUND: The prevalence and clinical characteristics of dermatomycosis are changed under the various influences such as geographic factor, social environment and development of therapy. OBJECTIVE: The purpose of this study was to evaluate the present status of dermatomycosis and changes on the prevalence, sex and age distribution and causative organisms. METHODS: We performed clinical and mycological studies on 7,568 cases of dermatomycosis among outpatients of Dermatologic clinic of Chonnam University Hospital for 10 years, from January 1991 to December 2000. RESULTS: The incidence of dermatomycosis was 17.6% of out-patients and show the highest incidence in the fourth decades (18.8%). The ratio of male to female was 1.3:1, showing slightly male-predominant pattern. The incidence of Tinea pedis (28.9%) was the highest, followed by Onychomycosis (16.3%), Tinea corporis (11.2%), Tinea cruris (10.1%), Tinea versicolor (9.3%), Tinea manus (8.0%), Candidiasis (6.9%), Tinea faciale (5.5%) and Tinea capitis (3.2%). Coexisting fungal infections were found 846 patients (11.2%) and the cases of Tinea pedis with onychomycosis were the most common. The positive rate of KOH examination was 50.8% and the positive rate of culture on Sabouraud's dextrose agar media was 31.4%. Trichophyton(T.) rubrum was the most common causative organism of dematomycosis (67.7%), followed by Candida albicans (13.0%), Microsporum(M.) canis (9.9%), T. mentagrophytes (7.4%), Epidermophyton floccosum (0.5%), M. gypseum (0.5%), T. verrucosum (0.4%), T. tonsurans (0.3%) and T. violaceum (0.2%). CONCLUSION: Compared with previous studies, the incidence of dermatomycosis increased, especially in females and was evenly distributed throughout all ages. The frequency of tinea pedis and tinea cruris decreased, but increased in onychomycosis.