ABSTRACT
Objective To investigate cancer high - risk rate,screening rate,detection rate in Zhejiang urban area and to provide the further evidence for cancer screening,early detection and treatment programs. Methods Epidemiological investigation and cancer risk evaluation were launched among 40 - 69 years old residents in Hangzhou and Ningbo city. People who were at high risk of lung cancer,liver cancer,upper digestive tract cancer,female breast cancer and colorectal cancer could receive clinical screening for free. Cancer high risk rates,screening rate and clinical detection rates were calculated. Results A total of 41 547 residents finished questionnaires and cancer risk evaluation. Cancer high risk rates of lung,liver,upper digestive,female breast and colorectal were 14. 05% ,12. 58% ,23. 28% ,11. 50% and 11. 82% , respectively. The rates of people who encountered single,couple,three,four and five types of cancer high risk were 29. 64% ,10. 97% ,3. 41% ,1. 16% ,0. 38% ,respectively. Screening rates for the five types of cancer were 50. 91% for lung cancer,49. 16% for liver cancer,19. 55% for upper digestive tract cancer,56. 25% for female breast cancer and 21. 75% for colorectal cancer. Lung cancer/ suspected lung cancer detection rate was 2. 42% . Breast cancer screening BI- RADS Grade 4 - 5 detection rate was 6. 71% . Upper digestive tract cancer detection rate was 0. 32% . Liver cancer detection rate was 0. 04% . Colorectal cancer detection rate was 0. 75% . Conclusion Technical solutions and program management should be improved to enhance the effect of cancer screening,early detection and treatment programs.
ABSTRACT
Objetivo: Caracterizar os candidatos quanto ao gênero e analisar a prevalência dos critérios de inaptidão adotados às doações de sangue, realizadas no Banco de Sangue Santa Maria, em Santa Maria, RS. Métodos: Dados retrospectivos arquivados foram avaliados, analisando-se os critérios de exclusão na triagem clínica e sorológica, no período de janeiro de 2005 até dezembro de 2010. Foram analisados 20.264 doadores. O estudo foi aprovado pelo Comitê de Ética e Pesquisa da Universidade Federal do Rio Grande do Sul-UFRGS, sob número de protocolo 18147. Resultados: Novecentos e setenta e seis (5%) candidatos foram considerados inaptos pela triagem clínica e 19.288 (95%) foram considerados aptos para prosseguirem com os testes laboratoriais. Dos doadores aptos, 941 (5%) foram excluídos na triagem sorológica, totalizando 18.347 bolsas de sangue disponíveis para uso. Predominaram os doadores do sexo masculino (62%) e a principal causa de exclusão, na triagem clínica, foi hipertensão (0,7%). Para a triagem sorológica, a principal causa de exclusão foi a Doença de Chagas (1,5%). Conclusão: Ressaltou-se a importância da triagem clínica, tendo em vista que ela excluiu 5% dos candidatos à doação e a relevância da triagem sorológica ser feita corretamente, evitando que resultados falso-negativos sejam liberados.
Objective: Characterize donors by gender and analyze theprevalence of the inability criteria of donations made at the SantaMaria Blood Bank, located at Santa Maria, Brazil. Methods: First,we searched historical data for exclusion criteria used in clinicaland serological screenings during the period from January, 2005 toJuly, 2010. We evaluated 20,264 blood donors' data for this study.The Ethical Committee of Rio Grande do Sul Federal UniversityUFRGSapproved this study under the protocol number 18147.Results: Nine hundred and seventy-six (5%) candidates wereconsidered unfit by the clinical screening and 19,288 (95%) wereconsidered fit. From the resulting fit population of the clinicalscreening, 941 (5%) were excluded from donating by the serologicalscreening, totaling 18.347 blood donations fit for use. The resultsshows that majority of the donors were male (62%) and the leadingcause of exclusion from donating in the clinical screening washypertension (0.7%). As for the serological screening, the leadingcause for exclusion was Chagas disease (1.5%). Conclusion: Thestudy stress the importance of the clinical screening process, giventhat it excluded 5% of blood donations, which were unfit for use. Wealso notice the relevance of a correctly done serological screening,thus avoiding that false-negative results are released.