"Brain-inspired intelligence" in dental implant decision-making / 口腔疾病防治

@#At present, implant surgery robots have basically achieved "surgical intelligence", but "brain-inspired intelligence" of robots is still in the stage of theory and exploration. The formulation of a clinical implantation plan depends on the timing of implantation, implantation area, bone condition, surgical procedure, patient factors, etc., which need to evaluate the corresponding clinical decision indicators and clinical pathways. Inspired by evidence-based medicine and the potential of big data and deep learning, combined with the data characteristics of clinical decision indicators and clinical pathways that can be quantitatively or qualitatively analyzed, this review simulates the cognitive behavior and neural mechanisms of the human brain and proposes a feasible brain-inspired intelligence scheme by predicting the decision indices and executing clinical pathways intelligently, that is, "select clinical indicators and clarify clinical pathways -- construct database -- use deep learning to intelligently predict decision indicators -- intelligent execution of clinical pathways -- brain-inspired intelligence of implant decision-making". Combined with the previous research results of our team, this review also describes the process of realization of brain-inspired intelligence for immediate implant timing decisions, providing an example of the comprehensive realization of brain-inspired intelligence of implant surgery robots in the future. In the future, how to excavate and summarize other clinical decision factors and select the best way to realize the automatic prediction of evidence-based clinical indicators and pathways and finally realize the complete intellectualization of clinical diagnosis and treatment processes will be one of the directions that dental clinicians need to strive for.

Aportes históricos de la neurociencia cognitiva y su emergencia en Chile

Very little has been written about the national pioneer investigators and the formal institutions and channels of knowledge that have contributed to the consolidation of cognitive neuroscience in Chile. This article is a review based on scientific publications, magazine articles and interviews with neuroscientists that were key to the development of cognitive neuroscience in Chile. In particular, the review incorporates information about the different Chilean investigators, the universities where they completed their doctoral studies, and the institutions where they settled afterwards. The objective of this article is to describe the way in which neuroscientific knowledge extended in Chile and to give recognition to pioneering scientists. The information retrieved was processed through the reconstruction of an interaction network between local and foreign neuroscientists, as well as their universities and institutions of origin, that contributed to the development of cognitive neuroscience in Chile. A visual representation of these networks was elaborated. In addition, the scientists' academic training in Chile and abroad is summarized in a table. This analysis allows for a deeper comprehension of the socio-historical context in which cognitive neuroscience emerges and encourages a critical perspective of its development in Chile.

Mental fatigue and ball sports: a narrative review focused on physical, technical, and tactical performance

Abstract Aim: This narrative review aimed to explore the effect of mental fatigue on physical, technical, and tactical performance in ball sports. Methods: Three Databases, PUBMED, SCOPUS, and SCIELO, were used to search for a scientific publication. The criterions adopted were: a) published in a peer-reviewed journal; b) adopted at least one manipulation check related to mental fatigue; c) mental fatigue induced by a cognitive task before the outcome task, and d) study participants were ball sports athletes. Result: The quality of this narrative review was rated at 11 (SANRA scale 0-12), and the papers analyzed were published between 2015 and 2022. Twenty-one experimental studies were included in this review. Most studies were in invasion sports (n = 13; 72%), and non-ecological tasks were used to induce mental fatigue (n = 15; 83%). Regarding performance in endurance tests, mentally fatigued athletes had performance impaired. However, when assessed during a small-sided or simulated game, data were inconclusive within the literature. Moreover, athletes presented attenuated perceptual skills (e.g., visual field). Consequently, this worsened motor skills, technical-tactical performances, and tactical behavior. Conclusions: Cognitively demanding tasks should be avoided before training and sports competitions because they can lead the athlete to mental fatigue and impair performance. This impairment is identified in physical performance (endurance tasks) and technical and tactical performance. Finally, it is recommended that athletes do not perform tasks that cause mental fatigue 2 h before the sports event.

Dispositional mindfulness, emotional regulation and perceived stress among nursing students / Mindfulness disposicional, regulación emocional y estrés percibido en estudiantes de enfermería / Atenção plena disposicional, regulação emocional e estresse percebido em estudantes de enfermagem

ABSTRACT Objective: To investigate the correlation between dispositional mindfulness, emotional regulation and perceived stress and to verify factors associated with dispositional mindfulness among nursing students. Method: A correlational, cross-sectional study with public undergraduate students. The following instruments were used: Mindful Attention Awareness Scale, Emotional Regulation Questionnaire and Perceived Stress Scale. Analyzes were performed using t tests, Pearson's correlation and multiple linear regression. Results: The study included 330 students. There was no correlation between dispositional mindfulness and general emotional regulation score and/or perceived stress and a weak correlation with the emotional regulation dimension emotional suppression. Being in psychological treatment and psychoactive substance use were associated with decreased dispositional mindfulness. Age, sufficient sleep hours and emotional suppression were associated with an increase in this variable. Conclusion: There was a relationship between dispositional mindfulness only with emotional suppression, in addition to the connection of this variable with the perception of sufficient sleep hours, age, use of alcohol or psychoactive substances, undergoing psychological/psychiatric follow-up and emotional suppression.

RESUMEN Objetivo: Investigar la correlación entre mindfulness disposicional, regulación emocional y estrés percibido y verificar factores asociados al mindfulness disposicional en estudiantes de enfermería. Método: Estudio transversal, correlacional con estudiantes de universidades públicas. Los instrumentos fueron utilizados: Mindful Attention Awareness Scale, Emotional Regulation Questionnaire y Perceived Stress Scale. Los análisis se realizaron mediante pruebas t, correlación de Pearson y regresión lineal múltiple. Resultados: Participaron 330 estudiantes. No hubo correlación entre mindfulness disposicional y puntuación general de regulación emocional y/o estrés percibido y una débil correlación con la dimensión de regulación emocional supresión de emociones. Estar en tratamiento psicológico y el consumo de sustancias psicoactivas se asociaron con una disminución del mindfulness disposicional. La edad, la suficiencia de horas de sueño y la supresión emocional se asociaron con un aumento de esta variable. Conclusión: Hubo relación entre el mindfulness disposicional solo con la supresión de emociones, además de la conexión de esta variable con la percepción de suficientes horas de sueño, edad, consumo de alcohol o sustancias psicoactivas, estar en seguimiento psicológico/psiquiátrico y supresión emocional.

RESUMO Objetivo: Investigar a correlação entre atenção plena disposicional, regulação emocional e estresse percebido e verificar fatores associados à atenção plena disposicional em estudantes de enfermagem. Método: Estudo correlacional, transversal, com estudantes de universidade pública. Foram utilizados os instrumentos: Mindful Attention Awareness Scale, Emotional Regulation Questionnaire e Perceived Stress Scale. Análises foram realizadas por meio de testes t, correlação de Pearson e regressão linear múltipla. Resultados: Participaram 330 estudantes. Identificou-se ausência de correlação entre a atenção plena disposicional e escore geral de regulação emocional e/ou estresse percebido e correlação fraca com a dimensão de regulação emocional supressão das emoções. Estar em tratamento psicológico e uso de substância psicoativas se associou à diminuição da atenção plena disposicional. Já idade, suficiência de horas de sono e supressão emocional se associaram ao aumento desta variável. Conclusão Houve relação entre a atenção plena disposicional apenas com a supressão das emoções, além de ligação desta variável com percepção de horas suficientes de sono, idade, uso de álcool ou substâncias psicoativas, estar em acompanhamento psicológico/psiquiátrico e supressão emocional.

Efectos de la intervención neurocognitiva en adultos mayores. Una revision sistemática / Effects of neurocognitive intervention in older adults. A systematic review

RESUMEN Fundamento La necesidad de la intervención neurocognitiva en adultos mayores, así como las diversas posturas en cuanto a sus beneficios, justifican la pertinencia de sistematizar las disímiles propuestas de intervención neurocognitiva en personas con y sin déficits cognitivos. Reviste vital importancia el conocimiento del impacto de dichas intervenciones en la salud cognitiva de estas personas. Objetivo describir, mediante una revisión sistemática de la literatura científica, los efectos de la intervención neurocognitiva sobre la salud cognitiva en adultos mayores sanos, y en adultos mayores con deterioro cognitivo leve o demencia. Métodos se realizó estudio descriptivo, que consistió en una revisión sistemática de la literatura científica sobre el tema; y partió de la búsqueda en las bases de datos: PubMed, PsycInfo, Scielo, Cochrane y EBSCO, de agosto a diciembre de 2018. Se empleó la Declaración PRISMA. Fueron encontrados 426 artículos. Tras aplicar los criterios de inclusión, exclusión y salida, y analizar el efecto de solapamiento, conformaron la muestra seis artículos. Resultados las principales formas de intervención neurocognitiva fueron la estimulación y el entrenamiento. La modalidad empleada con mayor frecuencia fue la estimulación neurocognitiva. Se reportaron efectos de mejora en la velocidad de procesamiento, en la atención selectiva, planeación, tiempo de reacción, categorización, fluidez verbal, comprensión, reconocimiento visual y orientación. Conclusión La evidencia empírica existente sobre la puesta en práctica de programas de intervención neurocognitiva durante los últimos diez años señala caminos hacia la intervención efectiva y la mejora de la calidad de vida de los adultos.

ABSTRACT Background The need for neurocognitive intervention in older adults, as well as the various positions regarding its benefits, justify the relevance of systematizing the dissimilar proposals for neurocognitive intervention in people with and without cognitive deficits. Knowledge of the impact of these interventions on the cognitive health of these people is vitally important. Objective to describe, through a systematic review of the scientific literature, the effects of neurocognitive intervention on cognitive health in healthy older adults, and in older adults with mild cognitive impairment or dementia. Methods a descriptive study was carried out, which consisted of a systematic review of the scientific literature on the subject; and started from the search in the databases: PubMed, PsycInfo, Scielo, Cochrane and EBSCO, from August to December 2018. The PRISMA Declaration was used. 426 articles were found. After applying the inclusion, exclusion and exit criteria, and analyzing the overlap effect, six articles made up the sample. Results the main forms of neurocognitive intervention were stimulation and training. The most frequently used modality was neurocognitive stimulation. Effects of improvement in processing speed, selective attention, planning, reaction time, categorization, verbal fluency, comprehension, visual recognition and orientation were reported. Conclusion The existing empirical evidence on the implementation of neurocognitive intervention programs during the last ten years points to paths towards effective intervention and improvement of the quality of life of adults.

Modulación del estado de ánimo a través de estímulos musicales activantes. Un diseño experimental con adultos jóvenes / Modulation of mood by activating musical stimuli. An experimental design with young adults

Resumen La música provoca respuestas emocionales que se ven reflejadas en los cambios fisiológicos y cognitivos de los oyentes. Es una temática de estudio en común entre distintas disciplinas como la psicología de la música, la musicoterapia, la antropología de la música y la la neuropsicología, entre otras. Entender de qué manera la música puede incidir en el estado de ánimo de las personas permite contribuir al conocimiento sobre el efecto comportamental y a la creación de nuevas técnicas orientadas para regular las emociones mediante la música. Teniendo en cuenta estos antecedentes, se realizó un estudio con el propósito de evaluar el efecto de la percepción de una pieza musical con características activantes (grupo experimental) versus ruido blanco (grupo control) como modulador del estado de ánimo, desde la perspectiva de las neurociencias, contando con la participación de adultos de entre 18 a 40 años. La inducción emocional de los participantes se realizó a través de la observación de imágenes con valencia emocional negativa. Posteriormente, y bajo una distribución al azar, un grupo de voluntarios escuchó la pieza musical activante y otro grupo escuchó el ruido blanco; ambos estímulos auditivos duraron 3 minutos. Se evaluó el estado emocional antes y después de la percepción auditiva. Los resultados analizados a través de pruebas no paramétricas (test de Wilcoxon) indicaron que la música con características activantes moduló emociones de tristeza y ansiedad, disminuyéndolas significativamente. Estos hallazgos sugieren que la percepción musical presenta potencialidades para la reducción del estrés, así como la ansiedad, brindando evidencia desde un enfoque neurocognitivo.

Abstract Music, from its several possibilities, induces emotional responses, which are reflected in the physiological and cognitive changes of the listeners, this is a thematic of study in common among different disciplines: music psychology, music therapy, music anthropology, neuropsychology, among others. At the neuroanatomical level, neuroimaging studies have shown that music can modulate the activity of limbic and paralimbic structures, that is, structures that are especially involved in the initiation, generation, maintenance, completion and modulation of emotions. Being able to understand how music can affect the mood of people allow us to contribute to the creation of new techniques oriented to emotional regulation through music. The current study was develop with the aim of evaluating the effect of perception of a musical piece, with activating characteristics (experimental group) vs. white noise (control group), as mood modulator, from a neurosientific perspective. Participated 29 young adults (55 % man), between 18 to 40 years old (. = 22.07, SD = .43), with no presence of neurological diseases or amusia, nor consumption of medications at the time of the study. The selection of the musical piece with activating characteristics was evaluated in a preliminary study, which counted with the participation of 24 young adults, who valued three pieces of music in terms of valence (emotion that the piece generated) and arousal (activation level). The 3 pieces were: "Tika Tika Walk" by Carlos D'alessio; "Leafmen" by Danny Elfman and "Define Dancing" by Thomas Newman. From this preliminary study, the activating stimulus that would be used for emotional modulation was selected ("Leafmen" by Danny Elfman). The emotional induction of the participants was carried out through the observation of 24 images with negative emotional valence (extracted from International Affective Picture System). About procedure, the study consisted of a single session of activity, divided into the following five phases: (1) information phase: participants signed the informed consent and completed the socio demographic questionnaire, (2) emotional induction phase: participants observed 24 negative images, and they had to rate each image from 0 to 10 (not arousing/emotional at all to highly arousing/emotional), (3) pre- measurement phase: participants completed a scale of mood, instrument used to measure transient moods, (4) perception phase: under a random distribution, a group of volunteers listened the activating music piece and another group listened the white noise (both for 3 minutes), and finally (5) post-measurement phase: participants completed a scale of mood after music or white noise perception. We analyzed the assumptions of normality and homogeneity of the sample using the statistics of Levenne and Shapiro Wilk. The results analyzed through non-parametric tests (Wilcoxon test, with a . value of .05). In the pre- measurement of mood, no significant differences were found between groups. Results of post- measurement phase indicated that music with activating characteristics, modulated the emotions of sadness and anxiety, decreasing them significantly. The results obtained indicate that music, specifically selected, aided as a modulator of emotions. It is important not to generalize the results obtained to the whole population, in this sense and thinking in future research, it would be necessary to expand the sample to a larger ., as well as to investigate this effect in other samples. The results obtained allow to open new paths in terms of the intrinsic qualities of music and its elements to promote relief of anxiety and stress, regulate moods and, promote motivation or enable the development of mechanisms to adapt to situations new and/or traumatic. Finally, it could be assumed that music constitutes an effective stimulus to modulate emotional responses, which are reflected in the mood changes of the listeners.

Non-verbal intelligence outperforms selective attention in a visual short-term memory test

Short-term memory is a dynamic psychological process that operates within a network in which non-verbal intelligence and attentional domains are connected. However, no consensus has been reached about which process has the greatest effect on this memory ability, which was the main objective of the present study. A sample of 1448 Brazilian participants (mean age = 26.62 years, standard deviation = 9.97 years; 53.9% females) were collectively tested on pen-and-paper standardized and validated measures of selective (ROTAS-C), alternating (ROTAS-A), and divided (ROTAS-D) attention. They also performed the R1 Non-verbal Intelligence Test and a visual short-term memory test (Memória Visual de Curto Prazo [MEMORE] test). The statistical analyses consisted of a data mining procedure, in which exhaustive automatic selection screening was performed. The results were compared with Corrected Akaike Information Criteria. The linear model met the classic assumptions of ordinary least squares and only included main effects of selective attention (standardized β = 0.39) and non-verbal intelligence (standardized β = 0.37) as main predictors (F2,39 = 7.01, p < 0.01, adjusted R2 = 24%). The results are discussed within a cognitive psychology framework. (AU)

Empatía y Teoría de la Mente: comparación entre deportistas y no deportistas / Empathy and Theory of the Mind: A Comparison between Athletes and Non-Athletes / Empatia e Teoria da Mente: comparação entre atletas e não atletas

Resumen Objetivo. Comparar la dimensión de cognición social de la Teoría de la Mente (ToM, por sus siglas en inglés) y la empatía entre deportistas y no deportistas. Método. Se ejecutó un diseño transversal con muestreo intencional, en el que 46 deportistas (Medad = 18.2, DE = 4.5) y 48 no deportistas (Medad= 20.2, DE = 3.5) completaron la Tarea de Empatía por el Dolor y el Test de las Miradas. Resultados. No se hallaron diferencias en la ToM, t(92) = 1.21, p = 0.228, d = 0.25. El Anova factorial mixto 3x2 indicó que el comportamiento de empatía es homogéneo por las condiciones (neutral, accidental e intencional) y grupos (deportistas vs no deportistas), F(2, 92) = 0.127, p = 0.881, ηp2 = 0.001. Sin embargo, la comparación de medias mostró diferencias favorables para deportistas en la condición de estímulos neutrales (p < 0.05). Conclusión. No hay variabilidad de la ToM, ni en las condiciones de accidentalidad e intencionalidad en el aspecto empático; mientras que en estímulos neutrales, el promedio difiere favorablemente para los deportistas.

Abstract Objective. To compare the social cognition dimension of Theory of Mind (ToM) and empathy between athletes and non-athletes. Method. A cross-sectional design was executed with intentional sampling, in which 46 athletes (Mage = 18.2, SD = 4.5) and 48 non-athletes (Mage = 20.2, SD= 3.5) completed the Empathy for Pain Task and the Gaze Test. Results. No differences were found in the ToM, t(92) = 1.21, p = 0.228, d = 0.25. The mixed factorial Anova, 3x2 indicated that the empathy behavior is homogeneous between conditions (neutral, accidental, and intentional) and groups (athletes and non-athletes), F(2, 92)= 0.127, p = 0.881, ηp2 = 0.001. However, the post-hoc analysis of Bonferroni showed favorable stimulus differences in neutral stimuli (p < 0.05). Conclusion. There is no variability of the ToM, and conditions of accident and intentionality at the empathic level; while in neutral condition the average differs favorably for athletes.

Resumo Escopo. Comparar a dimensão de cognição social da Teoria da Mente (ToM, por suas siglas em inglês) e a empatia entre atletas e não atletas. Metodologia. Foi executado um desenho transversal com amostragem intencional, no que 46 atletas (Midade= 18.2, DE = 4.5) e 48 não atletas (Midade = 20.2, DE = 3.5) completaram a Tarefa de Empatia pela dor e o Test das Miradas. Resultados. Não foram encontradas diferenças na ToM, t(92) = 1.21, p = 0.228, d = 0.25. O Anova fatorial misto 3x2 indicou que o comportamento de empatia é homogéneo pelas condições (neutral, acidental e intencional) e grupos (atletas vs não atletas) F(2, 92) = 0.127, p = 0.881, ηp2 = 0.001. Mesmo assim, a comparação de médias mostrou diferenças favoráveis para atleta na condição de estímulos neutrais (p < 0.05). Conclusão. Não tem variabilidade da ToM, nem nas condições de acidentalidade e intencionalidade no aspeto empático; enquanto que nos estímulos neutrais, a média difere favoravelmente para os atletas.

Estudo exploratório do ensino da neuropsicologia nos currículos dos cursos de graduação em fonoaudiologia / Exploratory study of the teaching of neuropsychology in the curricula of undergraduate courses in Speech-Language Pathology

RESUMO Objetivo Identificar a presença do ensino da neuropsicologia nos cursos de graduação em fonoaudiologia no Brasil através de uma análise exploratória dos currículos dos cursos de graduação. Método Estudo documental exploratório quantitativo. Foi realizada uma busca de documentos (projeto pedagógico de curso, ementário e/ou matriz curricular) nos websites das instituições de ensino superior públicas e privadas, ou via e-mail. A busca das informações necessárias para o estudo foi feita por três pesquisadores através de um checklist elaborado em consenso. Dessa maneira, pôde-se caracterizar as instituições de ensino e, posteriormente, foram investigadas quais delas ofereciam disciplinas que abordassem o tema da neuropsicologia através de uma busca pelo nome da disciplina. Foram exploradas associações entre a natureza da instituição de ensino superior, ano do projeto pedagógico de curso e região demográfica, com a presença de disciplinas sobre neuropsicologia. Resultados Foram incluídas no estudo 72 instituições de ensino, sendo que destas apenas nove ofereciam a disciplina de neuropsicologia. Nenhuma das associações testadas gerou diferença estatisticamente significativa. Conclusão Há uma carência na oferta de disciplinas de neuropsicologia para os estudantes de fonoaudiologia, e esta carência não tem relação nenhuma com a natureza da instituição de ensino superior, o ano do projeto pedagógico de curso ou com a região demográfica. Os achados chamam a atenção para a importância de um currículo que considere todo o escopo de atuação profissional e se ajuste à epidemiologia dos distúrbios da comunicação.

ABSTRACT Purpose To determine the level of teaching of neuropsychology within undergraduate courses of speech-language pathology in Brazil using an exploratory document analysis of the curricula of the undergraduate courses. Methods It is a quantitative exploratory document analysis. A review of available documents from websites and/or received from course directors (pedagogical course project, course content, and/or syllabus) of public and private universities in Brazil was carried out. Using an agreed consensus checklist, 3 researchers verified which universities offered subjects on neuropsychology by means of a search for the term 'neuropsychology' or neuropsychological'. Associations between type of university and region and the provision of neuropsychology courses were also explored. Results 72 universities were included in the study and only nine of them offered subjects on neuropsychology. None of the associations tested was statistically significant. Conclusion The provision of neuropsychology for speech-language pathology undergraduate students is limited, and not associated with the type of university, the year of the pedagogical course project, or the region in which the university is located. The findings call attention to the need to adapt undergraduate curricula in speech-language pathology to consider the entire scope of this profession and address the epidemiology of communication disorders.

Mecanismos Neurocognitivos de la motivación en el entrenamiento físico / Neurocognitive mechanisms of motivation in physical training

La inactividad física y el sedentarismo son en la actualidad un problema de salud global que preocupa por su crecimiento sistemático. Provoca consecuencias sanita-rias en los adultos y, con un incremento alarmante, en la población más joven. Por el contrario, la realización periódica de actividad física ha demostrado beneficios a la salud física, neurológica y mental. A pesar de los incontrovertibles datos sobre sus efectos positivos, menos de la mitad de la población mundial se ejercita regularmen-te. El objetivo de este trabajo es realizar una breve descripción sobre los mecanismos neurocognitivos que se encuentran implicados en los procesos de motivación, en es-pecial los que se vinculan a la actividad física, con la finalidad de presentar una serie de recomendaciones pragmáticas para aumentar la adherencia a programas de en-trenamiento físico, basados en técnicas de la psicología cognitiva y analizados desde la perspectiva neurocognitiva.

Physical inactivity and sedentary lifestyle are currently a global health problem that concerns because of its systematic growth, the health consequences it causes for adults and, in alarming escalation, also for the younger population. On the contrary, regu-lar physical activity has shown benefits to physical, neurological and mental health. Despite the incontrovertible information about its positive effects, less than half of the world's population excercises regularly. This work's objective is to make a brief description of the neurocognitive mechanisms that are involved in the motivational processes, especially those linked to physical activity, in order to present pragmatic recommendations that increase adherence to physical training programs, based on techniques of cognitive psychology and analyzed from a neurocognitive perspective.

La autorregulación en la primera infancia: avances desde la investigación / Self-regulation in early childhood: advances from research

Resumen Existe un robusto cuerpo de literatura que sustenta la importancia de desarrollar las habilidades de autorregulación (memoria de trabajo, atención y control inhibitorio) desde los primeros años, dada la vinculación que tiene tanto con los logros del presente como con el éxito futuro (p.e. adaptación al contexto escolar, logros académicos, participación social). Esta revisión tiene por objetivo sintetizar la información de la investigación neurocientífica en el tema de la autorregulación, entre los años 2000 y 2019, la cual ha aportado información para comprender mejor: (1) los procesos de desarrollo entre los 0 y 8 años, de cada una de estas habilidades mencionadas y (2) algunos de los factores que intervienen en este proceso. Los resultados confirman que tanto la madurez cronológica como las experiencias que tienen los niños, favorecerán el óptimo desarrollo de estas habilidades. Así también, se confirma que cada habilidad tiene su propio proceso y tiempo para emerger y consolidarse, lo que tiene una manifestación conductual y neurológica. En relación con los factores, existen algunos de orden biológico y otros contextuales o sociales que van a influir en cómo estas habilidades se desarrollan y se expresan en la vida cotidiana.

Abstract A robust body of literature confirms the importance of developing the skills of self-regulation (working memory, attention and inhibitory control) from the early years, considering their impact on the achievements of the present and future success (eg adaptation to the school context, academic achievements, social participation). The aim of this review is to summarize the information on neuroscientific research on the topic of self-regulation, between 2000 and 2019, which has provided information to better understanding: (1) development processes between 0 and 8 years of age, each of these skills mentioned and (2) some of the factors involved in this process. The results confirm that both the chronological maturity and the experiences of the children will favor the optimal development of these skills. Additionally, each skill emerges and takes roots according to its own processes and time frames, turning into behavioral and neurological manifestations. Relevant factors can be either biological or contextual/social that will influence how these skills are developed and expressed in everyday life.

Discalculia del desarrollo (DD) / Dyscalculia of development (DD)

Es relativamente reciente el interés por parte del ámbito científico con respecto al estudio de la cognición numérica. En la actualidad, los hallazgos provenientes de la neurociencia cognitiva y la psicología cognitiva se consideran aportes muy significativos para comprender el desarrollo de la competencia numérica y sus dificultades y a partir de esta evidencia científica, reducir la incertidumbre teórica en el diseño de estrategias de intervención psicopedagógicas y pedagógicas.

The interest of the scientific field with respect to the study of the numerical cognition is relatively recent. Currently, evidence from cognitive neuroscience and cognitive psychology are considered very significant contributions to understand the development of numerical competence and its difficulties and, based on this scientific evidence, to reduce the theoretical uncertainty in the design of psychopedagogical and pedagogical strategies.

Cross-cultural adaptation of the Revised Neurophysiology of Pain Questionnaire into Brazilian Portuguese language / Adaptação transcultural do Questionário Neurofisiológico da Dor revisado para língua portuguesa do Brasil

ABSTRACT Objective To perform a cross-cultural adaptation of the Neurophysiology of Pain Questionnaire for the Brazilian population (NPQ-BR). Methods A translation and cross-cultural adaptation study were conducted in 11 stages according to standard procedures. Descriptive and inferential statistics were performed. The internal consistency of the questionnaire was assessed using Cronbach's Alpha test (α). Results Four translators, six experts, twenty-one patients and ten physiotherapists participated in the study. The NPQ-BR was obtained after seven versions. The expert committee adapted four out of twelve items (item 1, 3, 11, and 12) to adapt the content of the instrument to the Brazilian context. The pre-test phase showed good internal consistency (α = 0.63). The comparison of the correct answers of the questionnaire between the groups (physical therapist group mean = 7.0 ± 1.7; patient group mean = 3.7 ± 2.1; p < 0.01) confirmed the discriminative validity of the NPQ-BR. Conclusion The Neurophysiology of Pain Questionnaire was cross-culturally adapted into a Brazilian context and can be used to assess the level of neurophysiological knowledge of pain of Brazilian patients. The interpretation of the results of the NPQ-BR must be taken with caution due to the absence of a robust validation methodology of the instrument.

RESUMO Objetivo Realizar a adaptação transcultural do Questionário Neurofisiológico de Dor (QND) para a população brasileira. Métodos Um estudo de tradução e adaptação transcultural foi conduzido em 11 estágios de acordo com procedimentos padronizados. Foi realizada estatística descritiva e inferencial. A consistência interna do questionário foi avaliada pelo teste de Alfa de Cronbach (α). Resultados Participaram do estudo quatro tradutores, seis especialistas, vinte e um pacientes e dez fisioterapeutas. A versão brasileira do QND foi obtida após sete versões. O comitê de especialistas adaptou quatro dos doze itens (item 1, 3, 11 e 12) para ajustar o conteúdo do instrumento ao contexto brasileiro. A fase de pré-teste evidenciou boa consistência interna (α = 0,63). A comparação dos acertos dos itens do questionário entre os grupos (média dos fisioterapeutas = 7,0 ± 1,7; média dos pacientes = 3,7 ± 2,1; p < 0,01) confirmou a validade discriminativa da versão brasileira do QND. Conclusão O Questionário Neurofisiológico de Dor revisado foi adaptado para o contexto brasileiro e pode ser utilizado para avaliar o nível de conhecimento neurofisiológico da dor de pacientes brasileiros. A interpretação dos resultados da versão brasileira do QND deve ser feita com cautela devido à ausência de metodologia robusta de validação do instrumento.

Brazilian version of the Cognitive Failures Questionnaire (CFQ): cross-cultural adaptation and evidence of validity and reliability

Objective: Cognitive failures are simple mistakes in routine activities, such as forgetting commitments and experiencing difficulty concentrating. The Cognitive Failures Questionnaire (CFQ) was designed to assess the frequency of these errors in everyday life. Although widely used in psychiatry and psychology, both in clinical and research settings, it has not been adapted for use in Brazil. Our objective was to perform cross-cultural adaptation of the CFQ for the Brazilian reality and assess its validity and reliability. Methods: The original version of the CFQ was translated into Brazilian Portuguese by two independent researchers, analyzed by a multidisciplinary board of experts, and back-translated into English. The final version was administered to 225 adults. Validity was assessed by correlation with the Self Reporting Questionnaire-20 (SRQ-20) and the Adult Attention Deficit/Hyperactivity Disorder Self-Report Scale (ASRS-18). Reliability was analyzed by calculating internal consistency and test-retest stability. Results: The adapted version of the CFQ showed significant correlations with SRQ-20 (r = -0.311), ASRS-18 inattention (r = 0.696), and hyperactivity/impulsivity (r = 0.405) scores. Reliability analysis suggests high internal consistency (0.906) and temporal stability (0.813). Conclusion: The Brazilian Portuguese version of the CFQ showed moderate correlations with other measures of mental health, as well as adequate reliability.

Diagnosing dementia in lower educated older persons: validation of a Brazilian Portuguese version of the Rowland Universal Dementia Assessment Scale (RUDAS)

Objective: To validate the Rowland Universal Dementia Assessment Scale for use in Brazil (RUDAS-BR). Methods: We first completed an English-Brazilian Portuguese translation and back-translation of the RUDAS. A total of 135 subjects over 60 years of age were included: 65 cognitively healthy and 70 with Alzheimer's disease (AD) according to the DSM-IV and Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria. All participants completed an interview and were screened for depression. The receiver operating characteristic curves of the RUDAS were compared with those of the Mini Mental State Examination (MMSE) regarding the sensitivity and specificity of cutoffs, taking education into consideration. Results: The areas under the curve were similar for the RUDAS-BR (0.87 [95%CI 0.82-0.93]) and the MMSE (0.84 [95%CI 0.7-0.90]). RUDAS-BR scores < 23 indicated dementia, with sensitivity of 81.5% and specificity of 76.1%. MMSE < 24 indicated dementia, with sensitivity of 72.3% and specificity of 78.9%. The cutoff score was influenced by years of education on the MMSE, but not on the RUDAS-BR. Conclusions: The RUDAS-BR is as accurate as the MMSE in screening for dementia. RUDAS-BR scores were not influenced by education. The RUDAS-BR may improve the cognitive assessment of older persons who are illiterate or of lower educational attainment.

El humanismo en la formación del médico. Papel de la neurociencia y la sicología cognitiva / Humanism in the training of the doctor. Role of neuroscience and cognitive psychology

The objective of this article is to present a proposal for professional training consistent with the vocation of the doctor. From the cognitive psychology and the neuroscience the praxis of the humanism is approached, without trying to deepen but to give motivating ideas that allow to transform the medical education with educational innovations. The article includes 3 components, a clinical case, a new view from neuroscience and cognitive psychology, and a proposal that welcomes these innovations directly related to humanism, to transform education in the classrooms and in the various practices of medicine and Health Sciences

El objetivo del presente artículo es exponer una propuesta para la formación profesional consecuente con la vocación del médico. Desde la psicología cogni- tiva y la neurociencia se aborda la praxis del humanismo, sin pretender profun- dizar sino dar unas ideas motivadoras que permitan transformar la educación médica con innovaciones educativas. El artículo comprende 3 componentes, un caso clínico, una nueva mirada desde la neurociencia y la sicología cognitiva, y una propuesta que acoja estas innovaciones directamente relacionadas con el humanismo, para transformar la educación en las aulas y en las diversas prácticas de medicina y las ciencias de la salud

Bioética e ampliação moral biotecnológica / Bioethics and biotechnical moral enhancement / Bioética y realce moral biotécnico

Resumen El acelerado desarrollo de la neurociencia abre expectativas para aplicaciones médico-terapéuticas en afecciones neurológicas y conductuales, aún muy incipientes y provisorias. Con más celeridad avanzan propuestas de intervenciones cerebrales para realzar cognición, memoria y aprendizaje. Usos y abusos, así como beneficios y riesgos de tales intervenciones de biorealce son analizados por la neuroética. En la literatura bioética reciente se debate sobre la necesidad urgente de un biorealce moral instrumental, dada la lentitud e insuficiencia de la maduración moral tradicional mediante educación y socialización, peligrosamente rezagada con respecto al desarrollo cognitivo de la tecnociencia por el riesgo de que potentes armas destructivas caigan en manos de personas y grupos dispuestos a generar catástrofes masivas. La bioética latinoamericana debe participar activamente en el debate del realce moral biotécnico, en vista de las consecuencias locales que presenta la investigación y eventual implementación de intervenciones cerebrales con fines morales.

Abstract The rapid development of neuroscience has given rise to expectations regarding the potential medical- therapeutic applications of neurological and behavioral diseases, which remain incipient and provisional. Proposals of cerebral interventions to enhance cognition, memory and learning, meanwhile, have advanced more quickly. Neuroethics analyzes the uses, abuses, benefits and risks of bioenhancement. Recent publications in bioethics journals have debated the urgent need for an instrumental and moral bioenhancement, due to the protracted and insufficient moral maturation achieved by the traditional processes of education and socialization, which have been too slow to meet the cognitive development of technoscience, due to the risk that such technology might fall into the hands of individuals and groups who wish to carry out actions with catastrophic results. Latin American bioethics must actively participate in the debate on the moral enhancement of biotechnology, in view of the local consequences of research and the potential implementation of cerebral interventions for moral ends.

Resumo O rápido desenvolvimento da neurociência estimula expectativas para aplicações médico-terapêuticas em doenças neurológicas e comportamentais, ainda muito incipientes e provisórias. Com maior rapidez avançam propostas de intervenções cerebrais para melhorar cognição, memória e aprendizagem. Usos e abusos, assim como benefícios e riscos de tais intervenções de ampliação são analisados pela neuroética. Na literatura bioética recente se debate sobre a necessidade urgente de uma bioampliação moral instrumental, dada a lentidão e insuficiência do amadurecimento moral tradicional mediante a educação e socialização, perigosamente atrasado em relação ao desenvolvimento cognitivo da tecnociência dado o risco de potentes armas destrutivas caírem nas mãos de pessoas e grupos dispostos a gerar catástrofes massivas. A bioética latino-americana deve participar ativamente do debate sobre a ampliação moral da biotecnologia, em vista das consequências locais da pesquisa e eventual implementação de intervenções cerebrais com fins morais.

Increased Ventrolateral Prefrontal Cortex Activation during Accurate Eyewitness Memory Retrieval: An Exploratory Functional Near-Infrared Spectroscopy Study / 대한법의학회지

We investigated the neural correlates of accurate eyewitness memory retrieval using functional near-infrared spectroscopy. We analyzed oxygenated hemoglobin (HbO₂) concentration in the prefrontal cortex during eyewitness memory retrieval task and examined regional HbO₂ differences between observed objects (target) and unobserved objects (lure). We found that target objects elicited increased activation in the bilateral ventrolateral prefrontal cortex, which is known for monitoring retrieval processing via bottom-up attentional processing. Our results suggest bottom-up attentional mechanisms could be different during accurate eyewitness memory retrieval. These findings indicate that investigating retrieval mechanisms using functional nearinfrared spectroscopy might be useful for establishing an accurate eyewitness recognition model.

The Assessment of Eyewitness Memory Using Electroencephalogram: Application of Machine Learning Algorithm / 대한법의학회지

This study was conducted to investigate whether memory accuracy can be assessed by analyzing electrophysiological responses (i.e., electroencephalography [EEG]) for retrieval cues related to the witnessed scene. Specifically, we examined the different patterns of EEG signals recorded during witnessed (target) and unwitnessed (lure) stimuli using event-related potential (ERP) analysis. Moreover, using multivariate pattern analysis, we also assessed how accurately single-trial EEG signals can classify target and lure stimuli. Participants watched a staged-crime video (theft crime), and the EEG signals evoked by the objects shown in the video were analyzed (n=56). Compared to the target stimulus, the lure stimulus elicited larger negative ERPs in frontal brain regions 300 to 500 milliseconds after the retrieval cue was presented. Furthermore, the EEG signals observed 450 to 500 milliseconds after the retrieval cue was presented showed the best classification performance related to eyewitness memory, with the mean classification accuracy being 56%. These results suggest that the knowledge and techniques of cognitive neuroscience can be used to estimate eyewitness memory accuracy.

Increased affective empathy in bipolar patients during a manic episode

Objective: To assess both cognitive and affective empathy in patients with bipolar disorder (BD) during an acute manic or depressive episode. Methods: The study included 25 patients with BD (aged 35±14 years) during an acute manic episode, 25 bipolar patients (aged 41±14 years) during a depressive episode, and 25 healthy control subjects (aged 36±11 years). Cognitive and affective empathy were assessed using the Multifaceted Empathy Test. Results: In both manic and depressive patients, a significant deficit in cognitive empathy was demonstrated. However, indices of affective empathy were significantly higher in the manic group than in depressed and control subjects. In the depressed patients, indices did not differ from those of healthy controls. For affective empathy, a significant positive correlation was found with intensity of manic symptoms and a negative correlation was found with intensity of depressive symptoms. No such correlations were observed with cognitive empathy. Conclusion: We found evidence of increased affective empathy (overempathizing) during a manic episode in bipolar patients. This phenomenon may be connected with disturbances in emotion inhibition related to anastrophic thinking and associated with increased activity of mirror neurons, all of which occur during a manic episode.