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CT colonoscopy is one of the recent advances in the field of Computed tomography with various post processing techniques. The aim of work is to evaluate and compare the role of CT colonoscopy and conventional colonoscopy in diagnosing and characterizing the colorectal malignancies. Subject and Methods:Our study included 50 patients with lower GI sypmtoms; 6 of them had colorectal malignancies. They ranged in age from 28 to 60 years. All patients were subjected to CT colonoscopy examination and results were compared to conventional colonoscopy and documented by histopathology in all cases. Results:The results in our study showed that CT colonoscopy has equal sensitivity and specificity in diagnosing colorectal malignancies when compared to conventional colonoscopy and further helps in delineating the locoregional extent of the lesion.
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Objective To investigate the effect of oral nutritional supplements (ONS) on body weight loss and life quality in post-discharge patients with gastric and colorectal cancer. Methods All the enrolled post-operative gastric or colorectal cancer patients were randomly divided into ONS group and control group. Body weight loss, middle arm circumference, triceps skinfold thickness and right-hand grip strength were measured and the Karnofsky score, ECOG score and QOL score were calculated 3 months after the discharge. ResultsThe body weight loss of gastric cancer patients was lower in ONS group than in control group since 2 months after discharge. (2 months after discharge: 1. 65±2. 11vs. 2. 70±1. 90 kg, t = -2. 3853, P = 0. 0193; 3 months after discharge: 1. 95±2. 75vs. 3. 67±2. 29 kg, t = -3. 1347, P = 0. 0024), There was no difference of body weight loss between two groups in colorectal cancer patients. The middle arm circumference, triceps skinfold thicknessand right-hand grip strength showed no statistic difference between two groups both in gastric and colorectal cancer patients. The Karnofsky score (56. 82±13. 65％vs. 51. 71± 9. 72％, t = 2. 0148, P = 0. 0472) and QOL score (41. 91±6. 92 vs. 38. 39±8. 77, t = 2. 0597, P = 0. 0426) were higher in ONS group than in control group in gastric cancer patients. While all 3 types of scores had no difference between two groups in colorectal cancer patients. Conclusion ONS can efficiently reduce the body weight loss and improve the performance status and life qualityin post-discharge gastric cancer patients, but not in colorectal cancer patients.
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Objective@#To investigate the effect of oral nutritional supplements(ONS) on body weight loss and life quality in post-discharge patients with gastric and colorectal cancer.@*Methods@#All the enrolled post-operative gastric or colorectal cancer patients were randomly divided into ONS group and control group. Body weight loss, middle arm circumference, triceps skinfold thickness and right-hand grip strength were measured and the Karnofsky score, ECOG score and QOL score were calculated 3 months after the discharge.@*Results@#The body weight loss of gastric cancer patients was lower in ONS group than in control group since 2 months after discharge.(2 months after discharge: 1.65±2.11vs. 2.70±1.90 kg, t=-2.385 3, P=0.019 3; 3 months after discharge: 1.95±2.75vs. 3.67±2.29 kg, t=-3.134 7, P=0.002 4), There was no difference of body weight loss between two groups in colorectal cancer patients. The middle arm circumference, triceps skinfold thicknessand right-hand grip strength showed no statistic difference between two groups both in gastric and colorectal cancer patients. The Karnofsky score(56.82±13.65%vs. 51.71±9.72%, t=2.014 8, P=0.047 2) and QOL score(41.91±6.92 vs. 38.39±8.77, t=2.059 7, P=0.042 6) were higher in ONS group than in control group in gastric cancer patients. While all 3 types of scores had no difference between two groups in colorectal cancer patients.@*Conclusion@#ONS can efficiently reduce the body weight loss and improve the performance status and life qualityin post-discharge gastric cancer patients, but not in colorectal cancer patients.
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Background: : Colorectal cancers being one of the leading causes of cancer related deaths in the world. Earlier it was thought that the colorectal cancers usually occur in older age groups. This thought has led to decrease in chances of malignancy in young patients. Therefore, we conducted this study of colorectal cancers in young patient to emphasise the importance of keeping in entity in mind while dealing with the patient presenting with complaints consistent with colorectal malignancy even if there age is less than forty year. Methods This study was a prospective cohort study of 30 cases of colorectal malignancy of age 40 years and below conducted in patients admitted in Department of Surgery at FH Medical College & Hospital, Tundla (UP), Firozabad, U.P. Results: In this study of colorectal cancers in young patient maximum number of patients were found in the age group of 31-40 years (70.4%) followed by in the age group of 21-30 years (27.57%)and 11-20 years (2.58%). Males were found to be affected more (59.76%) than females (41.23%). Most common site of involvement was found to be rectum (59.24%) followed by rectosigmoid (15.36%), caecum and descending colon (10.20%). Most common sign was found to be bleeding per rectum (71.24%) and most common symptom was found to be altered bowel habits (53%) followed by pain abdomen (62.58%). Mucinous adenocarcinoma (54.68%) was found to be most common histological type of colorectal malignancy followed by adenocarcinoma (46.35%). Conclusions: Our study was aimed at analysing colorectal malignancy in young patients. It should promote high index of suspicion on the part of treating surgeons about this entity even in young patients.
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Background: Colorectal cancers are one of the leading causes of cancer related deaths worldwide. Its a common knowledge that the colorectal cancers usually occur in older age groups. This has led to low index of suspicion of having this malignancy in young patients who are less than 40 years of age. We conducted this study of colorectal cancers in young patient to emphasise the importance of keeping in entity in mind while dealing with the patient presenting with complaints consistent with colorectal malignancy even if there age is less than forty year. the stage at which the diagnosis is made is of crucial importance in colorectal malignancy and a delayed diagnosis can have serious consequences for the patient. Objectives: (1) To determine incidence of colorectal malignancy in young patient. (2) To study the symptom complex (3) To determine sex and site distribution (4) To determine operability and respectability of tumour in young patients (5) To study the histopathological types and grading in young patients. Methods: This study was a prospective cohort study of 42 cases of colorectal malignancy of age 40 years and below conducted in patients admitted in department of surgery at a tertiary care institute. The duration of study was 2 years. Results: In this study of colorectal cancers in young patient maximum number of patients were found in the age group of 31-40 years (69.4%) followed by in the age group of 21-30 years (28.57%)and 11-20 years (2.38 %). Males were found to be affected more (54.76%) than females (45.23%). Most common site of involvement was found to be rectum(57.14%) followed by rectosigmoid (16.66%) , caecum and descending colon (11.90%).Most common sign was found to be bleeding per rectum (69.04%) and most common symptom was found to be altered bowel habits (50%) followed by pain abdomen (59.52%). Mucinous adenocarcinoma (52.38% ) was found to be most common histological type of colorectal malignancy followed by adenocarcinoma (42.85%). Most patients were diagnosed in Stage C (47.61%) of duke staging followed by stage B (23.80), stage D (19.04%) and stage A (9.52%). Metastasis were seen in 6 patients. 38 patients were operated. Most common surgical procedure done was abdominoperineal resection (11 patients) followed by Palliative sigmoid colostomy (10 patients ), Right hemicolectomy (5 patients), anterior resection (5 patients), while left colectomy and palliative transverse colectomy was done in 3 patients each. Only 1 patient underwent total proctocolectomy with ileostomy. 4 patients were not operated as they had advanced stages of the disease.Adjuvant chemotherapypy and radiotherapy was given in all patients except in 2 patients who had favourable histological stage and was under follow up. Total 9 patients died during follow up period. 2 refused treatment and 31 patients are still under follow up. Conclusion: Our study was aimed at analysing colorectal malignancy in young patients. It should promote high index of suspicion on the part of treating surgeons about this entity even in young patients.
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Aim: To study the CT characteristics of wall thickening in case of benign and malignant lesions of the colon and rectum, to evaluate the role of MDCT in pre-operative tumour stanging of colorectal malignancies and to evaluate the effectiveness of MDCT in differentiating benign and malignant colorectal lesions. Material and methods: It was correlative study done on patients with wall thickening involving the colon and rectum on CT were included. CT was performed using 16 slice SIEMENS SOMATRON Emotion CT scanner. CT findings were finally correlated with histopathology. Results: Patients with complaints of loose stools, vomiting, weight loss, constipation, bleeding PR, abdominal pain were evaluated by CT scan and which showed findings that were highly suggestive findings of malignancy like bowel wall thickening, presence of lymph nodes, peri-colic fat standing, infiltration of adjacent viscera and presence of metastases. Conclusion: MDCT is an excellent modality in the diagnosis and differentiation of benign and malignant lesions of the colon and rectum. MDCT is also useful in the staging of maligant lesions of the colon and rectum. MDCT is also useful in the staging of malignant lesions which helps in proper planning of surgery and further management of the patient.