ABSTRACT
Introduction: Controversies exist regarding comedogenicityand antimicrobial property of different oil. In Kerala, oilapplication to the face is a daily routine for many. Givingadvice to our acne patients regarding oil application hasalways been without much conviction. Study aimed to assessthe comedogenecity of coconut oil on rabbit ear.Material and methods: This study was conducted by theDermatology department in Amala Institute of MedicalSciences animal house, with the guidance from the researchdepartment. This study was conducted on rabbit ear model toassess comedogenic potential and antimicrobial properties ofcommonly used oils.Results: All the oils studied were equally comedogenic andshowed no antibacterial property.Conclusion: Application of coconut oil, mustard oil orliquid paraffin to acne prone skin is not advisable in ourenvironmental conditions and there is no antibacterial propertyfor any of these oils.
ABSTRACT
The present study was performed to evaluate the comedogenicity of several cosmetic ingredients, vegetable oils, steroid and sulfur. The test materials were applied to one ear canal of rabbits for 6 weekdays for 2 weeks. The results were as follows: l. Among the 14 cosmetic ingredients, no comedogenicity was shown in propylene glycol and petrolatum, mild comedogencity in squalene, acetylated lanolin, polyethylene glycol, cetyl aIcohol and Tween 80. Propylene glycol, sodium lauryl sulfate and oleic acid showed moderate comedogenicity. Severe comedogenicity was observed in myristyl myristate, isopropyl myristate, butyl stearate and myristyl lactate. 2. Moderate to severe comedogenicity was shown in olive oil, sesame oil and corn oil and moderate comedogenicity in sulfur (8%) and betamethasone dipropionate (0.06%) R. Histopathologic grading were paralleled the findings of the naked eye.