ABSTRACT
La mejora de la seguridad del paciente estuvo centrada durante el proceso de hospitalización; se prestó poca importancia al paciente ambulatorio, mientras que estudios recientes de meta análisis evidenciaron su importancia. Se proponen nuevas normas y procedimientos para prevenir eventos adversos en el paciente ambulatorio, tales como mejorar la relación medico paciente, y desarrollar indicadores de calidad y seguridad específicos del paciente ambulatorio.
The improvement of the safety of the patient was focused during the hospitalization; was given little importance to the outpatient, while recent studies by meta-analysis showed its importance. New rules were proposed and procedures to prevent adverse events in the outpatient, such as improve the relationship doctor patient, and develop specific indicators of quality and specific security of the outpatient.
Subject(s)
Patient Safety , Outpatients , Ambulatory Care/trends , Physician-Patient Relations , Ambulatory Care/methods , Medical Errors/prevention & control , Diagnostic Errors/prevention & control , Medication Errors/prevention & control , Health Records, PersonalABSTRACT
The valproic acid (VPA) animal model of autism spectrum disorder (ASD) is one of the most widely used animal model in the field. Like any other disease models, it can't model the totality of the features seen in autism. Then, is it valid to model autism? This model demonstrates many of the structural and behavioral features that can be observed in individuals with autism. These similarities enable the model to define relevant pathways of developmental dysregulation resulting from environmental manipulation. The uncovering of these complex pathways resulted to the growing pool of potential therapeutic candidates addressing the core symptoms of ASD. Here, we summarize the validity points of VPA that may or may not qualify it as a valid animal model of ASD.