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@#AIM:To explore the clinical efficacy of probing lacrimal passage combined with tobramycin eye drops in the treatment of congenital dacryocystitis. <p>METHODS: A total of 228 children(250 eyes)aged from 6mo-3a with congenital dacryocystitis treated in our hospital from January 2017 to June 2019 were included. They were assigned into three groups by age: 133 patients(149 eyes)aged from 6mo-1a(Group A), 62 patients(64 eyes)aged from 1-2a(Group B), and 33 patients(37 eyes)aged from 2-3a(Group C). All patients received lacrimal duct probing in surface anesthesia combined with postoperative tobramycin eye drops. <p>RESULTS: The probing cure rates of congenital dacryocystitis among there groups were 97.3%(Group A), 92.2%(Group B)and 83.8%(Group C), respectively. No adverse events reported. Through comparison of these three groups, the cure rate of children from 6mo-1a was the highest. The difference was statistically significant(<i>P</i>=0.009).<p>CONCLUSION: Lacrimal duct probing is effective in the treatment of congenital dacryocystitis, and it is safe and reliable to combine tobramycin eye drops(TOBREX)after surgery. The best time for treatment is 6mo-1a. The operation is simple, less complication, with high clinical value.
ABSTRACT
@#AIM: To investigate the clinical effect of probing lacrimal passage for congenital dacryocystitis in children. <p>METHODS: Totally 322 children(361 eyes)with congenital dacryocystitis treated in our hospital from January 2011 to December 2016 were selected and underwent lacrimal duct probing. The follow-up were taken on 1wk, 1 and 3mo after operation. <p>RESULTS: The cure rate of 322 cases(361 eyes)of congenital dacryocystitis was 99.2%(358 eyes); 3 eyes had nasolacrimal duct bony obstruction, 1 eyes had edema, 11 eyes had bleeding, and no other complications occurred. The success rate of once probing of children between 9 months to 18 months(85.0%, 204 eyes/240 eyes)was significantly higher than that of children older than 18 months(60.2%, 71 eyes/118 eyes), the difference was statistically significant(<i>χ</i><sup>2</sup>=27.387, <i>P</i><0.05). The one-time probing rate of multiple obstruction or adhesion of lacrimal duct was 4.4%(3 eyes/68 eyes), which was significantly lower than 94.1% of membranous obstruction at the lower end of lacrimal passage(273 eyes/290 eyes), the difference was statistically significant(<i>χ</i><sup>2</sup>=251.134, <i>P</i><0.05). <p>CONCLUSION: Lacrimal duct probing can be used for most congenital dacryocystitis and can relieve the symptoms of dacryocystitis effectively. The operation is simple, safe and reliable, but the therapeutic effect is closely related to the type of lacrimal passage obstruction.
ABSTRACT
In the present study, 37 eyes of 30 congenital dacryocystitis patients (7 bilateral) were studied, out of which 60% of patients were male and 40% female. Gram positive cocci constituted the major bacterial isolate (56.7%) with Streptococcus pneumoniae (27.9%) predominating. Most effective antibiotics against the commonest organism Streptococcus pneumoniae were Tobramycin and Gentamycin showing 100% effectivity. Staphylococcus albus 17.4% was the most common normal conjunctival commensal isolated.