ABSTRACT
Objective To analyze effect of the exercise reducting and improving fistula complications and the quality of life for continuous hemodialysis patients.Methods 106 patients with end-stage renal failure and hemodi-alysis were randomly divided into all 53 patients in observation group (using yoga exercise intervention)and 53 pa-tients in the control group (no intervention measures).Incidence of venous thrombosis,arterial thrombosis,false aneu-rysm,vascular complications were observed in patients of two groups.The quality of patients′life after dialysis care sit-uation in two groups was evaluated by a simple scale of health survey Mos SF-36.Results The comparison result of complication occurs case showed that the incidence of venous thrombosis,arterial thrombosis end,false aneurysm,vas-cular complications in the observation group were respectively 13.21%,0,3.77% and 20.75%;The same indexes were 33.96%,9.43 %,15.09% and 58.49% in the control group,and the complications in the observation group were significantly fewer than the control group (χ2 =6.33,5.15,3.98,10.44,P<0.01,P=0.02,P=0.04).the improved situation of life quality in the two groups showed physiological function,physical function,bodily pain,g en-eral health,vitality,social function,emotional function were significant differences before and after the mental health care in the observation group (t=5.05,4.57,2.85,6.95,10.06,3.28,6.71,8.11,P<0.01);in addition to the physiological functions in the control group,social function,the other were also statistically significant (t =2.42, 1.27,2.06,4.54,4.76,2.19,1.46,3.83P<0.02,P<0.05,P<0.01).In addition to the social function,other improvements in the observation group were better than that in the control group after the mental health care (t=3.06,3.59,2.02,3.79,7.14,1.74,4.22,2.25,P<0.05,P<0.01).Conclusion Through Yoga intervention continued dialysis,the patients'own immune system and disease resistance are improved,the patient's ability to withstand continuous hemodialysis are also improved,thereby to increase the effect of continued hemodialysis.
ABSTRACT
This article was aimed to discuss the mechanism of lactulose enema therapy to improve efficiency among maintenance hemodialysis (MHD) patients with uremic pruritus (UP) from the intervention of parathyroid hormone (PTH) and micro-inflammation state. A total of 60 cases of chronic kidney disease (CKD) stage 5, MHD patients with UP were randomly divided into 3 groups according to different intervention methods, which were the control group, loratadine and lactulose group. The integration of kidney disease treatment was adopted in the control group. In the loratadine group, on the basis of the control group medication, oral administration of loratadine, 10 mg/time, once a day, was combined. In the lactulose group, on the basis of the control group medication, lactulose enema, 30 mg/time, twice a day, was combined for 30 days. The pretreatment and posttreatment clinical curative effects were e-valuated among patients from 3 groups. Observation was also made on their itchy visual analogue scale (VAS) and serum PTH, high-sensitivity c-reactive protein (hs-CRP), tumor necrosis factor-α (TNF-α), interleukin 6 (IL-6) lev-el, respectively. The results showed that there were significant improvements on VAS, PTH and inflammation indexes (i.e., hs-CRP, TNF-α, IL-6) before and after treatment (P< 0.05 or P< 0.01). Compared to the control group, the posttreatment clinical total curative effects were significantly increased in both the loratadine group and lactulose group (P< 0.05); VAS, PTH and inflammation indexes (i.e., hs-CRP, TNF-α, IL-6) were significantly decreased (P< 0.05). There was no statistical difference of indexes mentioned above in the loratadine group and lactulose group. It was concluded that lactulose enema therapy improve PTH and micro-inflammation state among MHD patients with UP. It is one of the mechanisms to relieve skin itching.
ABSTRACT
OBJECTIVE To investigate the infection episode and related risk factors in continuous hemodialysis patients. METHODS The relationship among infection and etiologies of infection,nutritional status,pathogens and causes of chronic renal failure(CRF) were retrospectively analyzed in 180 continuous hemodialysis patients. RESULTS Totally 113 times infections were observed among the 86 inpatients under continuous hemodialysis.The main infectious site in hemodialysis patients was lungs.Thirty eight times were positive in 50 times of etiologic detection,Gram-negative germ was the most common(60.3%).Hemoglobin and serum albumin decreased obviously in infectious patients.Diabetes and systemic lupus erythematosus patients were more susceptible to infection.The hepatitis virus infections rate in hemodialysis patients was relatively high. CONCLUSIONS There is higher infections rate in continuous hemodialysis patients.Diabetes and systemic lupus erythematosus patients are more susceptible to infection.Anemia,lower serum albumin,old age and bad compliance are the susceptible factors.