Management of glycemia in patients with diabetes mellitus and chronic kidney disease / 医学研究生学报

Diabetes mellitus(DM) is a leading cause of chronic kidney disease(CKD) worldwide,and its rising prevalence may explain much of the increase in the incidence of kidney failure.Even when DM is not the cause of kidney disease,the coexistence of CKD and DM presents unique problems that need to be recognized and managed appropriately to optimize the outcomes.The objective of this article is to outline the management of glycemia in patients with DM of stage Ⅳ-Ⅴ and CKD ≥ stage Ⅲ,followed by a review of the appropriate use of available hypoglycemic agents for such patients,with an emphasis on the newer classes of the agents.