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The successful development and application of mRNA COVID-19 vaccine fully illustrated the great potential and application prospect of mRNA technology in the field of biomedicine. Currently, many companies worldwide are developing drugs and vaccines based on mRNA technology for the prevention and treatment of various diseases. It can be foreseen that with the continuous launch of mRNA drugs, commercial GMP production capacity matching them is also urgent. The optimization of production processes, intelligent manufacturing and other risk control strategies, as well as the control of industrialization costs, will help improve the core competitiveness of mRNA innovative drug development. In view of this, this article will provide an overview of the global production process of mRNA drugs and the progress of related GMP production dynamics, sort out the key chain points of the mRNA industry chain, explore the construction of the mRNA pharmaceutical enterprise value chain and the formation of core competitiveness, and provide reference and reference for the research and development of innovative mRNA drugs and high-quality development in China.
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Objective:To explore the internal and external factors that affect the core competitiveness of nursing degree graduates in China, and to put forward strategies for improvement.Methods:SWOT analysis method was used to analyze the strengths, weaknesses, external opportunities and threats of the core competitiveness of nursing graduates.Results:Students' own advantages include strong self-learning ability, strong scientific research thinking ability, strong education communication ability; disadvantages include inaccurate professional positioning, lack of clinical experience and professional quality; external opportunities include national policy attention, clinical platform demand, high attention of colleges and universities; threat factors include backward construction of teaching staff, lack of assessment methods and evaluation system, and lack of specialized curriculum system Characteristics of science and technology.Conclusion:The factors that affect the promotion of core competitiveness of professional degree nursing graduates in China cover two aspects: students themselves and training colleges and universities. We should make corresponding coping strategies on the basis of overall consideration of strengths and weaknesses, opportunities and challenges.
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OBJECTIVE：To define the core competitiveness of drug manufacturing enterprises ，and build its evaluation system. METHODS ：With“core competitiveness ”and“pharmaceutical”as Chinese and English keywords ，the laws ，policies and interpretation documents published on relevant Chinese government websites （from the inception/establishment of the database to June 2020，the same below ）were retrieved. Related literatures were collected from PubMed ，Embase，CBM，Wanfang database ， CNKI，VIP databases. The evidence-based research method was adopted to define the core competitiveness and elements of drug manufacturing enterprises. Based on above elements and retrieval method ，guideline database （National Guideline Clearinghouse ， Guidelines International Network ，Trip database ，The National Institute for Health and Care Excellence ）and systematic review ， health technology assessment （HTA），health economics evaluation research databases （NHS Economic Evaluation Database ，the Cochrane Library ，HTA，etc.）were retrieved. The output indexes of the core competitiveness of drug manufacturing enterprises were extracted ；according to the principles of scientificity ，hierarchy，comparability and comprehensiveness ，the evaluation system of core competitiveness of drug manufacturing enterprises was constructed. RESULTS & CONCLUSIONS ：The definition of core competitiveness of drug manufacturers is proposed as the strategic needs of the enterprises ，actively undertaking major national science and technology projects ，introducing top scientific and technological talents at home and abroad ，having independent intellectual property rights ，enhancing the ability of scientific and technological support ，strengthening original innovation ， increasing R&D investment ， strengthening key technology breakthrough ， perfecting the innovation mechanism of enterprises-univerisities-researches integration with enterprises as the main body. The elements included original innovation ， 60362951。 R&D investment and scientific and technological talents. Atotal of 25 original innovation output indexes [including two aspects of innovation system （such as national science and technology innovation base ，national laboratory ），innovation achievements （such as National Natural Science Award ， National Technological Invention Award ）]，1 R&D input-output indicator （R&D amount ），7 scientific and technological talent output indicators of production enterprises （such as those selected in the “National Million Talent Project ”，“National Outstanding Scientific and Technological Talents ”award） were extracted. The evaluation system composed of original innovation ，R&D investment and scientific and technological talents is constructed ，which can provide objective evaluation for core competitiveness of pharmaceutical manufacturing enterprises.
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Objective To understand the satisfaction degree of partial function outsourcing in a certain hospital of Xiaogan.Methods Through a questionnaire survey , SPSS20.0 was used to do statistical analysis .Results The satisfaction survey of outsourcing staff , the overall satisfaction rate was 9..7%, 96.5%after outsourcing .Investigation on medical quali-ty and patient satisfaction before and after the outsourcing and the outsourcing were 76.7%, after the outsourcing of 90.2%. Outsourcing personnel own happiness survey , assist doctors to job satisfaction was 91.0%, and on pay satisfaction was 82.5%, and turnover rate was 37.1%; Auxiliary nurses on the job satisfaction was 94.2%, and on pay satisfaction was 91.5%, and turnover rate was 29.4%.Conclusion Description of the survey , public hospitals under the limited re-sources, only to keep and develop the most competitive advantage of core resources , will be part of the non core outsourcing , which is adapt to the new management mode of market economy .It is the hospital to reduce costs , improve performance , to enhance the core competitiveness and enhance their adaptability to the environment , and all has the important practical signif-icance.
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Based on the development trend of the three -in-one system of “medical treatment, teaching and scientific re-search”, the main university affiliated hospitals at home and abroad need to ensure the sustaining development of hospital scientific re-search and improve the core competitiveness of hospital by improving the scientific research management , such as focusing more atten-tion on the scientific research policy , improving the quality of management staff , constructing the diversification mechanism , integra-ting resources, constructing information platform, managing the funds and archives, and strengthening the whole process supervision.
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Objective To explore the validity of simulative employment training course on enhancing the core competitiveness of university students.Method We investigate the students with simulative employment trainin, graduates and recruiters through interview, symposium and questionnaire survey. Results The comprehensive quality and occupational capacity of students that completed simulative employment training had been improved. In the simulative employment training course,98%students thought their interview skills had been promoted, 90%recruiters were satisfied with the students,95%graduates who had worked consider that the simulative employment training were helpful. Conclusions Simulative employment training is effective for enhancing the core competitiveness of university students.
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OBJECTIVE:To provide a new idea for enhancement of core competitiveness of pharmaceutical enterprises in China and supply advice for building virtual marketing network.METHODS:The concept and theory of virtual management and virtual marketing network were interpreted and analyzed according to the status quo of pharmaceutical enterprises in China.RESULTS & CONCLUSION:Virtual marketing network is a new idea for the development of pharmaceutical enterprises.Enterprises should establish a standard cooperative relation with the dealers in order to prevent risks and promote core competitiveness of enterprises.
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OBJECTIVE: To provide reference for research and evaluation of core competitiveness of drug research institute. METHODS: Based on the literature review and integrated analysis on the related evaluation methods both at home and abroad, the establishing of evaluation system of core competitiveness of drug research institute was discussed. RESULTS & CONCLUSIONS: The establishment of evaluation system is of great importance to the understanding and improving of the core competitiveness of drug research institute, however, whether the estsablished evaluation system can fully reflect the core competitiveness of drug research institute or not remains to be further tested and improved.
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Future competition in the medical market will in essence be the contest of the core competitiveness of hospitals.It is therefore imperative for hospitals to do a good job in the following aspects in light of trends in medical development,the state of its resources and the needs of the market: enhancing their awareness of the importance of scientific and technological work,setting up a rationally distributed scientific research system,strengthening personnel and disciplinary development,improving the quality of scientific and technological management personnel,and establishing standardized systems for scientific and technological management.The goal is to enhance core competitiveness so as to gain competitive edges for sustainable development.
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By analyzing the situation of market competition by modern hospitals, the paper identifies the core competitiveness of the hospital as the key force to be nurtured and promoted by the hospital in its competition in the medical services market; the basic force that spaces out service levels and profits of hospitals at the same level; the unique cultural force shaped by the hospital in a long period of time; the dynamic force rising constantly to mans needs for medical and health care; the main force driving the sustainable development of the hospital in market competition. The paper also proposes five major core competitive capacities to be especially nurtured and promoted by the hospital, viz. the integrative capacity in management, the influencing capacity of specialized fields, the fighting capacity of the team, the cohesive capacity of culture, and the scheming capacity for marketing.
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The development of medical institutes needs not only marvelous hardware construction,but also software strength,such as the hospital culture,brand establishment,etc.Only by the persistent and coordinated development of hardware strength and software strength,can hospital's comprehensive strength and core competitiveness be effectively improved.To enhance hospital software strength,it is necessary to cultivate hospital culture with unique features,emphasize brand establishment,devise long-term development blueprint of medical institutes and activate hospital's potential for further development.