ABSTRACT
Introduction: Cataract is a major cause of impaired vision andblindness. Study aimed to find out if there is any associationbetween dyslipidemia and cataract.Material and methods: This cross sectional hospital basedstudy was performed in a tertiary care center of Jharkhandbetween June 2017 to March 2018. Total 223 patients whowere diagnosed with senile cataract were included in the study.Detailed history, ophthalmologic and systemic examinationwas done. Dyslipidemia is defined as:Hypercholesterolemia(total cholesterol > 220 mg/dl), or Hypertriglyceridemia (totaltriglyceride > 150 mg/dl), or Low density lipoprotein > 130mg/dl.Results: Out of total 223 patients 134 were men and 89were women. 70% patients had dyslipidemia. Prevalenceof dyslipidemia was associated significantly (< 0.05) withnuclear and cortical cataract but not significant (> 0.05) forposterior sub capsular cataract.Conclusion: Dyslipidemia maybe considered having anassociation with nuclear and cortical cataract directly orindirectly.
ABSTRACT
Background With the progression of cortical cataract,the lens thickness and anterior chamber will change and may have significant influences on the structure and function of the eyes.A special measurement is needed to observe the anterior and posterior surface of lens and detailed angle structure,and to quantify these changes.Ohjective This study was to compare the lens thickness and angle structures by CASIA SS-1000 anterior segment optical coherence tomography (AS-OCT) in early and intumescent stage of cataract and quantify the ocular anatomical differences.Methods An observational study was performed.Fifty cortical cataract patients (87 eyes) of the early stage or the intumescent stage in the ophthalmology outpatient clinic of Daping Hospital from October 16 to October 30,2015 were continuously enrolled in this research.The eyes were assigned to the early stage group (28 patients 44 eyes) and the intumescent stage group (22 patients 43 eyes) according to the slit lamp examination results.The average age was (56.46 ± 12.90) years in the early stage group and (70.95 ± 8.81) years in the intumescent stage group.With the use of CASIA SS-1000 AS-OCT measurements,lens thickness,angle opening distance (AOD),angle recess area (ARA),trabecular-iris space area (TISA),trabecular-iris angle (TIA) and anterior chamber depth (ACD) were measured and compared between the two groups.Results Lens thickness was (4.438±0.487) mm in the early stage group and (5.094±0.451)mm in the intumescent stage group,with an average increase of (0.656±0.101) mm,showing a significant difference between the two groups (t =-6.513,P =0.000).ACD in the early stage group was (2.966±0.326)mm and (2.534±0.376)mm in the intumescent stage group,with an average decrease of (0.432±0.075)mm,showing a significant difference between the two groups (t =5.730,P =0.000).AOD500,AOD750,ARA500,ARA750,TISA500,TISA750,TIA500 and TIA750 were all lower in the intumescent stage group than those in the early stage group,with significant differences between the two groups (all at P=0.000).Conclusions The lens was thicker,ACD was shallower and anterior angle was narrower in the intumescent stage than those in the early stage of cortical cataract patients.SS-1000 AS-OCT is efficiency with high definition,and is supposed to have promising prospect of clinical application.
ABSTRACT
To estimate change of blood constituents in cataract patients, the authors retrospectively reviewed medical records of catatract and non-cataract patients.We selected 199 pairs of cataract and non-cataract patients matched in age and sex.We compared the presence of diabetes, hepatitis B antigen and hepatitis C antibody, also other blood chemistry values between cataract and non-cataract patients group and also between cortical and noncortical patients group. Results are as follows:In cataract patients group, ALP (alkaline phosphatase) albumin/total protein-albumin ratio and K (potassium)were higher, and Na (sodium), total biilrubin and total protein were lower than in non-cataract patients.And in cortical cataract patients, AST (aspartate aminotransferase), BUN (Blood Urea Nitrogen), total calcium, Cr (creatinine), K and Cl (chloride) were higher and albumin/total protein-albumin ratio was lower than in noncortical cataract patietns.