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We case of acute bilateral central serous chorioretinopathy (CSCR) after receiving the first dose of Covishield vaccine in a young, otherwise healthy male with no associated risk factors.
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Background: A massive global human disaster has been created by a recent contagious respiratory infectious disease caused by a novel coronavirus (SARS-CoV-2). The most effective way of controlling infectious diseases is often vaccination. Public vaccine hesitancy is a big problem for public health authorities. Present study was designed to assess the attitudes and hesitancy toward Covid -19 vaccine among healthcare workers and medical students of RUHS-College of Medical Sciences. Material and methods: It was an observational, questionnaire-based study carried out under the department of Pharmacology, RUHS-college of medical sciences Jaipur. The study tool was consists of a digital questionnaire which was prepared in English language. Result: The present study was carried out among 521 health care workers. In this study 48.9% participants were completely agree 31.9% somewhat agree, 13.6% neutral,3.5% somewhat disagree and 2.1% completely disagree to accept covid-19 vaccine without prior employer recommendation. After employer recommendation covid-19 vaccine acceptance was increased. Now 54% participants were completely agree to accept covid-19 vaccine. Hesitancy to covid-19 vaccine was maximal due to possible side effects (65.5%). Conclusions: Acceptability of vaccination in our participants was increased after awareness to vaccine. So by increasing awareness for acceptance of covid-19 vaccine, we can prevent mass rejection of covid-19 vaccine in general population during vaccination program. Vaccine hesitancy must be addressed for successful implementation of covid-19 vaccination program in future
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The whole world waiting for the elimination of COVID?19. This is a short series of three cases that presented with optic neuritis. On further inquiry, all had received the Covishield vaccine within 5–12 days just before the presentation, with no history of COVID?19 positive RT?PCR. The range of age was 27–48 years. All patients improved after pulse steroid therapy and are still under follow?up. After being plagued by COVID?19 for nearly 2 years, the whole world wishes for little more than complete eradication of the disease. Our country commenced the much?awaited vaccination drive from Jan 2021. Ophthalmic manifestations have appeared in many forms post?COVID?19, among which neuro?ophthalmic manifestations are infrequent. To the best of our knowledge, this is the first report of a short case series from our country presenting with optic neuritis after COVID?19 vaccination, without any sign of active infection
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Background: As there were no vaccines available for any strains of coronaviruses, it was inevitable to develop safe and effective vaccines for the prevention of infection. There were limited data on the safety of the vaccine in the real-world environment, so the present study is undertaken to assess the safety of the vaccine. Aim and Objectives: The objective of the study is to evaluate the safety profile of ChAdOx1-nCoV-19 Coronavirus Vaccine (Covishield) among health care professionals. Materials and Methods: This is 6 months follow-up observation of vaccinated individuals, 545 health care workers have taken Covishield Vaccine for a duration of 1 month in a tertiary care hospital in two doses with 28 days apart. Demographic data such as age, gender, and comorbidities were noted. They were given a World Health Organization-based Adverse Event Following Immunization form to fill if they have any of the symptoms. Their phone numbers were collected to check for any adverse reactions every week after the first dose till the next dose and every month for another 6 months. Results: Adverse reactions were reported by 147 out of 297 vaccinated individuals after the first dose, 40 members out of 248 individuals after the second dose 24 h after vaccination. Pain at the site of infection and body ache/myalgia was seen in 27% of individuals. Reactions were mild in most of the individuals which resolved in a day without medication. Conclusions: Although the frequency of adverse reactions was observed in more individuals, they were mostly mild and self-limiting. This may show that vaccine has an acceptable safety profile in our observation among health care professionals.
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Introduction: Covid-19 pandemic is further spreading its leg in India. Indigenous Covishield vaccination drive was started to protect people from the disease. Objective: This observational cross sectional study was conducted to assess the morbidity and mortality pattern amongst Covishield vaccinated people Vs non-vaccinated patients of covid19. Methodology: This observation study was conducted in a dedicated covid-19 hospital. All RTPCR covid-19 patients were included. The data on vaccination against covid-19 amongst the patients was obtained, and analysed using statistical software. Results: The study population comprised of 155 cases of confirmed covid-19 patients of which 24 (15.48%) were fully vaccinated, however 41 (26.45%) and 90 (58.06%) were partially and non-vaccinated respectively. Fully vaccinated people were protected from development of severe form of disease (X2=9.57, d.f=2, p=0.0083). Mortality was significantly less amongst vaccinated group (X2=4.83, d.f=1, p= 0.028). Conclusion: Patients who are completely vaccinated with Covishield vaccine are protected from development of severe form of diseases and deaths and hence mass vaccination of Indian population to overcome the pandemic is required at the earliest.
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Covishield is in wide use in India with about 80% efficacy. Serious side effects are still under study. A 30-year-old female presented to us 7 days post-vaccination with a 5-day history of sudden diminution of vision in both eyes. The clinical findings were suggestive of the Vogt-Koyanagi-Harada (VKH) syndrome. She was treated with high-dose oral steroids. At this juncture, the association was unclear. However, it was justified by an acute flare-up of uveitis on day 2 post the second dose of vaccination despite ongoing steroids. A direct correlation of Harada-like syndrome with the Covishield vaccine is observed here