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@#Objective To explore the effect of cranial electrotherapy stimulation (CES) on cognitive function for old patients with mild cognitive impairment.Methods A total of 40 old inpatients with mild cognitive impairment in 2018 and 2019 were randomly divided into control group (n = 20) and treatment group (n = 20). Both groups accepted routine medication (without cognitive drugs), and the treatment group accepted CES in addition, for eight weeks. They were assessed with modified Barthel Index (MBI) and Montreal Cognitive Assessment (MoCA) by two researchers single-blind before treatment, and four and eight weeks after treatment. The control group accepted free CES after trial.Results For MoCA score, the main effect was significant in time (F = 5.603, P = 0.007), not significant in group (F = 2.160, P = 0.150), and the effect of interaction was significant (F = 9.160, P < 0.001), which was more in the treatment group than in the control group. For MBI score, the main effects were not significant both in time (F = 0.322, P = 0.726) and in group (F = 0.009, P = 0.925), nor the effect of interaction (F = 0.322, P = 0.726). No adverse reactions occurred during CES intervention.Conclusion CES may be effective on mild cognitive impairment in old patients.
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OBJECTIVE@#To observe the therapeutic effect of acupuncture combined with cranial electrotherapy stimulation (CES) on generalized anxiety disorder (GAD).@*METHODS@#A total of 200 patients with GAD were randomized into an acupuncture+CES group, an acupuncture group, a CES group and a medication group, 50 cases in each one. In the medication group, patients were treated with tandospirone citrate tablet orally, 10 mg after breakfast, lunch and dinner respectively. In the CES group, CES was adopted by SCS brain electromedical instrument, 60 min each time, once a day. In the acupuncture group, acupuncture was applied to Baihui (GV 20), Sishencong (EX-HN 1), Yintang (GV 29), Shenting (GV 24), etc., 30 min each time, once a day. In the acupuncture+CES group, CES was adopted before acupuncture. Treatment of sixty days was required in the 4 groups. Before and after treatment, the scores of Hamilton anxiety scale (HAMA), World Health Organization's quality of life questionnaire-brief version (WHOQOL-BREF) and treatment emergent symptom scale (TESS) were observed, the clinical effect was evaluated, and the relapse of anxiety during follow-up of 1 year after treatment was recorded in the 4 groups.@*RESULTS@#Compared before treatment, the scores of HAMA after treatment were decreased (@*CONCLUSION@#Acupuncture combined with CES can effectively relieve the symptoms in patients with GAD, improve the quality of life, reduce the occurrence of adverse reactions and the relapse rate, and its clinical effect is obviously superior to the western medication, the simple application of acupuncture or CES.
Subject(s)
Humans , Acupuncture Points , Acupuncture Therapy , Anxiety Disorders/therapy , Electric Stimulation Therapy , Quality of Life , Treatment OutcomeABSTRACT
OBJECTIVES: To investigate the therapeutic effect of cranial electrotherapy stimulation (CES) with sleep hygiene in patients with chronic insomnia. METHODS: This study was designed as a prospective, double-blinded, and randomized controlled trial. Twenty-seven patients with chronic insomnia were recruited and randomly allocated to two groups; cranial microcurrent therapy (MC) group and sham group. All patients received sleep hygiene education. Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) were measured at baseline (pre-treatment), and 2 weeks and 4 weeks of treatment. RESULTS: In MC group, the PSQI and ISI showed a tendency to decrease consistently until 4 weeks of treatment. In sham group, PSQI and ISI initially decreased during the first 2 weeks, but it increased after 2 weeks of treatment. CONCLUSIONS: This study showed that combination treatment of CES and sleep hygiene is more effective in treating chronic insomnia than sleep hygiene only as demonstrated by improvement and maintenance of sleep score for 1 month.
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Humans , Education , Electric Stimulation Therapy , Hygiene , Prospective Studies , Sleep Initiation and Maintenance DisordersABSTRACT
ABSTRACT: Introduction: Obesity, a global pandemic, has been reported as a potential cause of various diseases, including high blood pressure, type-2 diabetes, and cardiovascular disease. Objective: The purpose of the present research was to investigate the effects of eight weeks of regular aerobic exercise and cranial electrotherapy stimulation (CES) on the stress-related hormone, the neurotrophic factor, and mood states in obese women. Method: The subjects for this study were 36 obese middle-aged Korean women. Subjects were randomly divided into a control group (CON, n = 12), an aerobic exercise group (EX, n = 12), and an aerobic exercise and CES group (EX + CES, n = 12). CES was conducted with a micro current cranial electrotherapy stimulator for 20 minutes at 100 μA and 0.5 Hz. Aerobic exercise consisted of treadmill running for 40 minutes at 70% of the subjects' heart rate reserve (HRR). Mood state was measured by the profile of mood states (POMS) questionnaire, and blood collection was performed to examine levels of stress-related hormones (cortisol and adrenocorticotropic hormone [ACTH]) and neurotrophic factors (brain-derived neurotrophic factor [BDNF] and nerve growth factor [NGF]) before and after each intervention. Results: Plasma cortisol levels, as well as scores for Tension-Anxiety, Depression-Dejection, and Fatigue-Inertia were significantly decreased after intervention when compared with pre-intervention measurements in the EX and EX+CES groups (p < .05). Serum BDNF levels, serum NGF levels, and Vigor-Activity scores were significantly increased after intervention when compared with pre-intervention measurements in the EX and EX+CES groups (p < .05). However, there was no significant difference in these findings between the EX and EX+CES groups (p > .05). Discussion and conclusion: These results suggest that aerobic exercise training could improve the mood state of obese middle-aged women through a decrease in serum cortisol and an increase in serum BDNF and NGF.
RESUMEN: Introducción: La obesidad, una pandemia mundial, se ha reportado como una posible causa de diversas enfermedades, incluyendo presión arterial alta, diabetes tipo 2 y enfermedades cardiovasculares. Objetivo: El objetivo del presente trabajo fue investigar los efectos de ocho semanas de ejercicio aeróbico regular y la estimulación eléctrica craneal (CES) sobre la hormona relacionada con el estrés, el factor neurotrófico, y los estados de ánimo en mujeres obesas. Método: Los sujetos de este estudio fueron 36 mujeres coreanas de mediana edad con obesidad. Los sujetos fueron divididos aleatoriamente en un grupo control (CON, n = 12), un grupo de ejercicio aeróbico (EX, n = 12) y un grupo de ejercicio y CES aeróbico grupo (EX + CES, n = 12). CES se llevó a cabo con una corriente estimulador de electroterapia craneal micro durante 20 minutos a 100 μA y 0,5 Hz. El ejercicio aeróbico consistía en carrera en cinta rodante durante 40 minutos a 70% de reserva de frecuencia cardíaca de los sujetos (HRR). El estado de ánimo se midió por el perfil de los estados de ánimo (POMS), y la extracción de sangre se realizó para examinar los niveles de las hormonas relacionadas con el estrés (cortisol y la hormona adrenocorticotrópica [ACTH]) y factores neurotróficos (factor neurotrófico derivado del cerebro [BDNF] y factor de crecimiento nervioso [NGF]) antes y después de cada intervención. Resultados: Los niveles de cortisol en plasma, así como las puntuaciones de tensión-ansiedad, depresión, abatimiento, y fatiga-inercia, se redujeron significativamente después de la intervención, en comparación con las mediciones previas a la intervención en los grupos EX y EX + CES (p < .05). Los niveles séricos de BDNF, los niveles de NGF en suero y las puntuaciones Vigor-Actividad aumentaron significativamente después de la intervención, en comparación con las mediciones previas a la intervención en los grupos EX y EX+CES (p < .05). Sin embargo, no hubo diferencia significativa en estos hallazgos entre la EX y los grupos EX + CES (p > .05). Discusión y conclusión: Estos resultados sugieren que el entrenamiento con ejercicio aeróbico podría mejorar el estado de ánimo de las mujeres obesas de mediana edad por medio de una disminución en el cortisol sérico y un aumento en el suero BDNF y NGF.
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BACKGROUND/AIMS: A large number of studies have shown that function constipation (FC) has an extremely high incidence of mental and psychological disorders. Cranial electrotherapy stimulation (CES) was applied to the treatment of psychological disorders such as anxiety and depression. We explored the effects of CES combined with biofeedback therapy (BFT) on the psychological state, clinical symptoms, and anorectal function in patients with FC. METHODS: A total of 74 patients with FC were randomly divided into 2 groups. The control group received BFT. CES combined with BFT was carried out in the experiment group. All patients were assessed using the self-rating anxiety scale (SAS), self-rating depression scale (SDS), and Wexner constipation score at baseline and the end of each course. Anorectal manometry and balloon expulsion tests were performed before and after treatment. RESULTS: After treatment, the participants in the experiment group had significantly lower score SAS, SDS, and Wexner constipation scores than the control group (all P < 0.05). The number of successful expulsion in the experiment group was larger than the control group (P = 0.016). CONCLUSIONS: CES combined with BFT was effective in improving the psychological status of anxiety, depression, and bowel symptoms in patients with FC.
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Humans , Anxiety , Biofeedback, Psychology , Constipation , Depression , Electric Stimulation Therapy , Incidence , Manometry , Treatment OutcomeABSTRACT
BACKGROUND: Cranial electrotherapy stimulation is used as a treatment for depression, anxiety, insomnia, and adjunctive intervention for pain management. The aim of this study is to evaluate the effect of cranial electrotherapy stimulation pretreatment on the level of preoperative anxiety and the hemodynamic responses. METHODS: Sixty patients undergoing general anesthesia were randomly assigned into two groups to receive either no pretreatment (Control group, n = 30) or cranial electrotherapy stimulation pretreatment (CES group, n = 30). Anxiety score, systolic and diastolic blood pressure, and heart rate were measured in the preoperative holding area and the operating room. RESULTS: The anxiety score in the operating room compared with the preoperative holding area decreased in the CES group, but increased in the Control group. Systolic blood pressure and heart rate in the operating room were lower in the CES group compared with the Control group. CONCLUSIONS: Cranial electrotherapy stimulation pretreatment reduced the level of the preoperative anxiety and the hemodynamic responses.