ABSTRACT
Objective: To study the chemical constituents from the stems and leaves of Cryptolepis buchananii. Methods: Compounds were isolated and purified by chromatography on silica gel, Sephadex LH-20, ODS columns, and preparative HPLC. Their structures were identified by NMR and MS, as well as comparison on spectral data with literature values. Results: Thirteen compounds were obtained from the EtOAc fraction of methanol extract in the stems and leaves of C. buchananii and their structures were elucidated as isoscopoletin (1), (+)-3-hydroxy-β-ionone (2), (3R, 6R, 7E)-3-hydroxy-4, 7-megastigmadien-9-one (3), ficusic acid (4), (+)-pinoresinol (5), (+)-8-hydroxypinoresinol (6), (+)-syringaresinol (7), diaaurantiamide acetate (8), loliolide (9), (-)-balanophonin (10), chrysoeriol (11), 9-hydroxy-10E, 12Z-octadecadienoic acid methyl ester (12), and ficusesquilignan A (13). Conclusion: All the compounds are isolated from the plants of Cryptolepis R. Br. for the first time.