Development of Index System for Assessing Parent s Ability on Child Injury Prevention by Delphi consultation / 中国学校卫生

Objective@#To construct and determine the weight of Index System for Assessing Parent s Ability on Child Injury Prevention, and to provide the basis for childhood injury intervention in family.@*Methods@#Twenty four experts majored in related fields were invited to participate in Delphi consultation. The final index system was constructed according to the consulting results and the weight of primary and secondary indicators were calculated.@*Results@#The final index system consisted of 5 subscales corresponding to 5 age groups: 0,1-2,3-5,6-11 and 12-17 years old. Each scale included 4 primary indicators and 11 secondary indicators. The weight of primary indicators obtained by analytic hierarchy process is 0.28 for "environment", 0.16 for "product", 0.31 for "behaviors and skills", and 0.25 for "psychology". The highest weight of secondary indicators for "environment", "product" and "behaviors and skills" was "water area", while the top secondary indicators for "psychology" included "parental style""emotional control" "family atmosphere", with all indicators weighted higher than 0.2.@*Conclusion@#The Index System for Assessing Parent s Ability on Child Injury Prevention by Delphi consultation is comprehensive in content, and with the focus on parental behaviors and skills on injury prevention.

Cuidado a los adolescentes institucionalizados: perspectiva de las madres cuidadoras

RESUMEN Objetivo: Describir el cuidado a los adolescentes institucionalizados desde la perspectiva de madres cuidadoras en un centro de atención residencial de Chiclayo, Perú. Material y Método: Investigación cualitativa descriptiva, con muestreo no probabilístico, por conveniencia y saturación, cuyas participantes, previo consentimiento informado, fueron 10 madres cuidadoras de un centro de atención residencial y a quienes se les aplicó una entrevista semiestructurada, validada mediante juicio de tres expertos. El rigor se sustentó en los criterios de credibilidad, auditabilidad y transferibilidad. Resultados: Se identificaron 3 categorías: a) Cumplimiento de los requerimientos nutricionales y monitorización de la higiene personal, b) Afecto y comunicación asertiva para reeducar en valores y c) Apoyo en las tareas del rol de la vida diaria. Conclusión: Las madres cuidadoras asumen la función como lo haría una madre biológica, coordinando con todos los profesionales que allí trabajan, y en equipo intentan formar o reformar a un adolescente separado de su familia consanguínea por orden judicial al carecer de un entorno favorable para su crecimiento y desarrollo. De este modo realizan un conjunto de actividades para satisfacer las necesidades primordiales y afectivas, inculcan disciplina y valores, y el cumplimiento del rol diario de vida para su autosuperación. También propician actividades recreativas y deportivas. Incluso hay indicios que fortalecen la fe a través de la oración y actúa para coordinar siempre con todos los profesionales que allí trabajan, en especial con la enfermera, quien es la responsable de velar por la salud integral de estos adolescentes.

ABSTRACT Objective: To describe the care for institutionalized adolescents from the perspective of caregiving women in a residential care center in Chiclayo, Peru. Material and Method: Descriptive qualitative research, with non-probabilistic sampling, using convenience and saturation. Participants consisted of 10 caregiving women of a residential care center, who signed prior informed consent and responded a semi-structured interview validated by three experts. Rigor was based on the criteria of credibility, auditability and transferability. Results: 3 categories were identified: a) Compliance with nutritional requirements and monitoring of personal hygiene, b) Affection and assertive communication to re-educate in values and c) Support in daily life tasks. Conclusion: Caregivers act as biological mothers, coordinating with other professionals working at the care center. They try to educate or re-educate an adolescent separated from his or her biological family after a court ruling decision due to lack of a favorable environment for his or her growth and development. In this way, they carry out different activities to satisfy the primary and affective needs, instill discipline and values, as well as encourage self-improvement through daily tasks. They also promote recreational and sports activities. There are even indications that caregivers strengthen faith through prayer and work in coordination with other professionals, especially with the nurses who are responsible for the general health of adolescents.

RESUMO Objetivo: Descrever o cuidado a adolescentes institucionalizados na perspectiva de cuidadores de um centro residencial de saúde em Chiclayo, Peru. Material e Método: Pesquisa qualitativa descritiva, com amostragem não probabilística, por conveniência e saturação, cujos participantes, com consentimento informado prévio, foram 10 cuidadores de um centro de assistência residencial e aos quais foi aplicada uma entrevista semiestruturada, validada por julgamento de três especialistas. O rigor baseou-se nos critérios de credibilidade, auditabilidade e transferibilidade. Resultados: Foram identificadas 3 categorias: a) Cumprimento das necessidades nutricionais e acompanhamento da higiene pessoal, b) Afeto e comunicação assertiva para reeducar em valores e c) Apoio nas tarefas do papel da vida diária. Conclusão: As mães cuidadoras assumem o papel de mãe biológica, articulandose com todos os profissionais que ali atuam, e em equipe procuram formar ou reformar o adolescente separado de sua família consanguínea por ordem judicial por falta de um ambiente favorável para seu crescimento e desenvolvimento. Dessa forma, realizam um conjunto de atividades para a satisfação das necessidades primordiais e afetivas, inculcam disciplina e valores, e o cumprimento do papel cotidiano da vida para o seu crescimento pessoal. Eles também promovem atividades recreativas e esportivas. Há até sinais que fortalecem a fé por meio da oração e agem em articulação sempre com todos os profissionais que ali trabalham, principalmente com o enfermeiro, que é responsável por zelar pela saúde integral desses adolescentes.

Challenges for the implementation of the chain of custody for rape victims in the Federal District / Desafíos para implantación de la cadena de custodia para víctimas de violación en el Distrito Federal / Desafios para implantação da cadeia de custódia para as vítimas de estupro no Distrito Federal

Abstract Chain of Custody implies adequate collection, recording, and storage of the vestige of sexual violence, guaranteeing the reliability of the material that will be forwarded as expert evidence. Its implementation in the Unified Health System has faced challenges. Objective: To know the attendance to victims of sexual violence in the public maternity of Federal District and evaluate the knowledge of the team about the legislation on a chain of custody. Method: Cross-sectional, quantitative, and descriptive study with 134 medical and nursing professionals working in the obstetric emergency, who answered a questionnaire, submitted to descriptive statistical analysis and the Qui-Square Test. Results: Of the 78.95% of professionals who reported attending to victims of sexual violence, 25.71% consulted in 10 minutes, and 14.18% received specific training. The situational diagnosis reveals that the care is superficial, centered on medical issues, and the collection of vestiges is non-existent. Conclusion and implications to nursing practice: A generalized change of posture is necessary so that it is possible to implant the chain of custody in the maternity studied. It is essential to develop care beyond medical issues, and which includes forensics. It is suggested a collaborative action between physicians and nurses, with nursing as the epicenter of this process.

Resumen La Cadena de Custodia implica el adecuado proceso de recolección, registro y almacenamiento del vestigio de la violencia sexual, garantizando confiabilidad al material encaminado como prueba pericial. Su instalación en el Sistema Unico de Salud ha enfrentado desafíos. Objetivos: Conocer la atención a la víctima de violencia sexual en maternidad pública del Distrito Federal y evaluar el conocimiento del equipo acerca de la legislación sobre cadena de custodia. Método: Estudio transversal, cuantitativo y descriptivo, con 134 profesionales de medicina y enfermería actuantes en la emergencia obstétrica, que respondieron un cuestionario, sometido al análisis estadístico descriptivo y al Test Qui-Cuadrado. Resultados: Entre el 78,95% de los profesionales que afirmaron atender a víctimas de violación, 25,71% las consultan en 10 minutos y 14.18% recibieron capacitación específica. El diagnóstico situacional revela que la atención es superficial, centrada en cuestiones médicas y la recolección de vestigios es inexistente. Conclusión e implicaciones para la práctica de enfermería: Un cambio generalizado de postura es necesario para posibilitar la implantación de la cadena de custodia en la maternidad estudiada. Es fundamental desarrollar una atención más allá de cuestiones médicas y que incluya cuestiones periciales. Se sugiere una actuación colaborativa entre médicos y enfermeros, teniendo la enfermería como epicentro de ese proceso.

Resumo A Cadeia de Custódia implica no adequado processo de coleta, registro e armazenagem do vestígio da violência sexual, garantindo a confiabilidade do material que será encaminhado como prova pericial. Sua instalação no Sistema Único de Saúde tem enfrentado desafios. Objetivos: Conhecer o atendimento à vítima de violência sexual em maternidade pública do DF e avaliar o conhecimento da equipe acerca da legislação sobre cadeia de custódia. Método: Estudo transversal, quantitativo e descritivo, com 134 profissionais de medicina e enfermagem que atuam na emergência obstétrica, que responderam a um questionário, submetido à análise estatística descritiva e o Teste Qui-Quadrado. Resultados: Dentre os 78,95% dos profissionais que afirmaram atender vítimas de violência sexual, 25,71% as consultam em 10 minutos e 14.18% receberam capacitação específica. O diagnóstico situacional revela que o atendimento é superficial, centrado em questões médicas e a coleta de vestígios é inexistente. Conclusão e implicações para a prática de enfermagem: Uma mudança generalizada de postura é necessária para que seja possível implantar a cadeia de custódia na maternidade estudada. É fundamental desenvolver um o atendimento para além de questões médicas, e que inclua questões periciais. Sugere-se uma atuação colaborativa entre médicos e enfermeiros, tendo a enfermagem como epicentro desse processo.

Evaluation of diagnostic accuracy of ultra-miniaturized pocket ultrasound device on cardiac function in critically ill patients / 解放军医学杂志

Objective: To compare the diagnostic accuracy of a new ultra-miniaturized pocket ultrasound device (PUD) (Vscan™, GE Healthcare, Wauwatosa, WI) and conventional high-quality echocardiography system (Vivid q™, GE Healthcare) for a cardiac focused ultrasonography in critical patients. Methods: The patients admitted to our hospital and receiving transthoracic echocardiography (TTE) using a PUD and a conventional echocardiography system were included in this study during the 10 months from December 2013 to October 2014. Each examination was performed independently by an intensive care unit (ICU) physician and an experienced ultrasound doctor, unaware of the results found by the alternative device. The following parameters were assessed: global cardiac systolic function, identification of ventricular size, whether or not accompanying enlargement or hypertrophy, assessment for the morphology of cardiac valves and its function, pericardial effusion and estimation of the inferior vena cava (IVC) diameter. The time-consuming of each device were recorded. Results: One hundred and twenty-eight patients were included in the study. Their left ventricular wall motion abnormalities, global left ventricular systolic dysfunction, pericardial effusion, IVC dilation were assessed by PUD and the assessment results were highly consistent with those by Vivid q (κ>0.84). The consistency was slightly lower in evaluating the left and right ventricular size. For evaluating the cardiac valves function, the agreement of two devices were relatively low (κ=0.69-0.84). Compared with Vivid q, PUD took less time (4.7± 1.4min vs 6.3± 2.6min; P<0.05). Conclusion: PUD can provide fast, reliable cardiac examination, thus being an effective method for ICU physicians to assess the cardiac function in critical patients.

The relationship between blood pressure variability and neurological deterioration during the acute phase in hypertensive minor ischemic stroke patients / 天津医药

Objective To investigate the relationship between blood pressure variability (BPV) and neurological deteri?oration (ND) during the acute phase in patients with hypertensive minor ischemic stroke. Methods A total of 200 hyperten?sive patients with acute minor ischemic stroke were recruited in this study. Patients were divided into two groups: stable group (n=182) and deterioration group (n=18) according to the neurological prognosis. Values of BPV in 24 h ambulatory blood pressure, 24 h systolic blood pressure variation coefficient (24 h CVSBP), 24 h diastolic blood pressure variation coeffi?cient (24 h CVDBP), day time systolic blood pressure variation coefficient (dCVSBP), day time diastolic blood pressure variation coefficient (dCVDBP), night time systolic blood pressure variability (nCVSBP) and night time diastolic blood pressure variability (nCVDBP) were compared between two groups. The related factors of BPV were analyzed by binary logistic method in the acute phase of patients with hypertensive minor ischemic stroke. Results There were significantly higher levels of 24 h CVSBP [17.75%(17.54%,19.26%) vs 12.78% (10.67%,14.39%)], 24 h CVDBP [25.48%(20.77%,27.87%) vs 17.95% (14.88%, 21.46%)], dCVSBP [18.61%(17.65%,20.65%) vs 12.30%(10.10%,14.75%)], dCVDBP [25.65%(21.25%,29.78%) vs 17.76%(14.89%,22.19%)] in deterioration group than those of stable group (P<0.01). Results of binary logistic regression analysis showed that values of 24 h CVSBP and dCVSBP were risk factors for neurological deterioration in the acute phase of patients with hypertensive minor ischemic stroke. Conclusion The increased 24 h BPV and day time BPV are correlated with neurologi?cal deterioration during the acute phase in hypertensive minor ischemic stroke patients. BPV should be concerned in the acute phase and secondary prevention in patients with ischemic stroke.

Reflection and investigation on the current situation of remote fetal monitoring system in primary hospital / 中国基层医药

Objective To study the feasibility and care mode of remote fetal monitoring at primary hospital. Methods A questionnaire survey was administered to 71 hospitals of different levels in Jiangsu province.Question-naire content included human resources status of midwifery,the remote fetal monitoring system and its clinical applica-tion;anonymous questionnaire survey was conducted to 130 maternal women by random cluster sampling;investigation of remote fetal monitoring device type,operation mode,clinical usage and existing problems was done through the doc-ument retrieval of VIP and Wanfang data platform.Results In grade Ⅱhospital,obstetricians sufficient and insuffi-cient were 10 cases (24.39%),31 cases(75.6%),respectively,and in grade Ⅲ hospital were 8 cases (61.53%), 5 cases (38.46%),respectively,there was statistically significant difference between grade Ⅱ and grade Ⅲ hospital (χ2 =4.572,P 0.05).Different cultural lev-el,place of residence,occupation of maternal demand for the development of remote fetal monitoring were urgent and higher degree of acceptance,but the cognition was not comprehensive,college degree or above,technical personnel and urban pregnant women that their need for remote fetal monitoring were the most urgent.There were significant differ-ences(all P <0.01).The use of remote fetal monitoring equipment was mostly at tertiary hospital nationwide.3G net-work way to transfer data had short time and small scope.Conclusion The existing monitoring system and service mode can not meet the requirements of the implementation of remote fetal monitoring,medical personnel professional quality and maternal comprehensive quality are the main influencing factors.The primary hospitals should actively pro-mote the application of remote fetal monitoring,maternal health care services and health education should arouse the attention of the whole society.

Study on the change of brain edema in intracerebral hemorrhage by non-invasive and dynamical method / 中国基层医药

Objective To observe the change of comprehensive agitating coefficient in the intracerebral hem -orrhage( ICH) patients monitoring by non-invasive cerebral edema and dynamical method ,and to find out dynamical change of cerebral edema in patients with ICH ,and to evaluate the specificity and sensitivity of non-invasive dynami-cal brain edema monitor in ICH treatment .Methods The change of comprehensive agitating coefficient in 130 patients was detected by non-invasive dynamical brain edema monitor at day 1,3,5 and 7 from ICH onset.Results The comprehensive agitating coefficient in focus side was lower than the unaffected side in both groups at the first day .The coefficient in the focus side was higher than the unaffected side at the third day ,and then became approximately equal at day 5 and basically normal at day 7.The comprehensive agitating coefficients in focus side were significantly differ-ent to unaffected side at day 3,5(P<0.01),and quite different at day 1,7(P<0.05).Conclusion The compre-hensive disturbance coefficient takes on dynamical changes in the ICH and reflects the course of edema formation . Cerebral edema monitoring by non-invasive and dynamical method can evaluate the course of cerebral edema ,and has a guiding role to the therapy of the ICH .

Predictive risk factors associated with prolonged stay in the intensive care unit for patients undergoing coronary artery bypass grafting surgery / 中华胸心血管外科杂志

Objective The rate of post -operative complications has been increased with the changes in patients' age,prolonged duration, more severe and diffused lesions, and more patients with complications in recent years. We try to identify the risk factors associated with prolonged stay in the intensive care unit ( ICU ) after coronary artery bypass graft surgery (CABG). Methods 1623 patients who received CABG surgery in Beijing Anzhen Hospital Between June 1, 2006 and December 31,2007 were divided into two groups based on their stay duration in the ICU. Prolonged stay in ICU was defined as 5days or more. Univariate and multivariate analysis ( logistic regression) were used to identify the risk factors. The discrimination and calibration of the result were tested after the risk factors were determined. Results Fifty one patients had prolonged ICU stay, accounting for 3.14% of total cases. Multivariate logistic analysis showed that the age of patients, peripheral vascular diseases, critical status before operation, LVEF, operative status, mitral regurgitation, postoperative respiratory failure,postoperative renal failure, secondary thoracotomy for postoperative bleeding were associated risk factors. Conclusion Prolonged ICU stay after CABG surgery can be predicted based on the above factors. For patients with these risk factors, more pre-and postoperative care strategies are needed.

Predictive risk factors for prolonged stay in intensive care unit in patients undergoing coronary artery bypass grafting surgery / 中华胸心血管外科杂志

Objective To describe the preoperative factors of prolonged intensive care unit length of stay after coronary artery bypass grafting. Methods From 1997 to 2009, 1318 patients underwent isolated CABG in our hospital. Retrospective analysis was performed on these cases. Univariate and multivariate analyses for preoperative risk factors were performed. Prolonged length of ICU stay was defined as initial admission to ICU exceeding 72 h. Results The mean age of patients ( 322women and 996 men) was (67.4±9.4) years. Of 1318 patients undergoing isolated CABG from 1997 to 2009, 205 experienced prolonged length of ICU stay. The length of ICU stay was (40.1 ± 22.5 ) hours and ( 122.6 ± 48.7 ) hours separately.Overall in-hospital mortality was higher among these 205 patients ( 13.7% vs. 1.2%, P ＜0.05 ). The overall mortality was 3.1%. In univariate analyses, there were statistically significant differences with respect to the percentage of CPB, total bypass time, cross-clamp time, number of distal anastomoses, use of pressor agent, use of intro-aortic balloon pump,time of ventilation and hospital mortality. The significant risk factors were age, NYHA class Ⅲ/Ⅳ, left ventricular ejection fraction(LVEF) ＜0.40, renal failure, cerebrovascular and/or peripheral vascular disease, chronic obstructive pulmonary disease, recent acute myocardial infarction, prior percutaneous coronary intervention, left main stenosi, three-vessels disease. The variables entered into the multivariate logistic regression were age, NYHA class Ⅲ/Ⅳ, LVEF ＜0.40, renal failure, chronic obstructive pulmonary disease, recent acute myocardial infarction, prior percutaneous coronary intervention, three-vessels disease. According to the outcome of multivariate logistic regression, we can conclude the model of probability forecast and create a new variable named Pre. The area under ROC curve of the new variable Pre was larger than other variables. Conclusion The main risk factors of prolonged ICU length of stay were LVEF ＜ 0.40, recent acute myocardial infarction, renal failure and chronic obstructive pulmorary disease. The AUC of variable Pre was higher than other' s , which indicated that new variable Pre combining each variable was more valuable than single variable with respect to prediction. A predicted probability of 0. 754 was used as cut-off point for the prognostic test.

Correlative study on gastrointestinal symptoms of severe eases and Abdominal compartment syndrome / 中华护理杂志

ObjectiveTo explore the correlation of gastrointestinal symptom of severe cases and abdominal compartment syndrome (ACS),improve monitor technique. MethodsUsing descriptive study to do classified description according to the distribution of 384 severe cases' gastrointestinal symptom and using regressive analysis to analyze the dangerous factors of 46 cases who suffered ACS. Results①The rate of gastrointestinal symptom of 46 cases with ACS:one case with nausea and vomiting occupied 2.2％ ,45 cases with abdominal distension and pain occupied 97.8％ ,45 cases with bowel sound occupied 97.8％,2 cases with diarrhea occupied 4.3％,45 cases with constipation occupied 97.8％. ②Aceording to the single factor logistic regressive analysis shows statistical significant symptoms relating to ACS as follows:abdominal distension and pain,bowel sound decline and constipation,etc. With multi-factors unconditional progressively logistic regressive analysis shows:the first dangerous factor of ACS is abdominal distension and pain(OR=259.106),then is bowel sound decline. CondusionThe correlation exists between the gastrointestinal symptoms and ACS. The clinical nurses should pay attention to the monitor of gastrointestinal function so that the incidence of ACS can be reduced through promoting monitor skills.

The clinical significance of deceleration of rate of fetal heart in non-stress test / 中国医师进修杂志

Objective To analyse the clinical significance of variable deceleration and extended deceleration in non-stress test. Methods Studied the clinical characteristics of variable deceleration and extended deceleration of 200 cases who underwent non-stress test from January 2005 to December 2007, and compared corresponding clinical significance and newborn prognosis. Results Variable deceleration and extended deceleration in non-stress test dued to cord entanglement, polyhydramnios and fetal growth restriction. The occurrence of fetal distress and severe asphyxia in nowbom were less in low-grade variable deceleration (8.3%, 1.0%) than those in high-grade variable deceleration (17.7%, 4.8%)and extended deceleration (23.8%, 7.1%). Condusion Variable deceleration and extended deceleration in non-stress test due to cord entanglement mostly, low-grade variable deceleration is not always clue to fetal distress and high-grade variable deceleration and extended deceleration is often clue to fetal distress.

The nursing care of the mechanical ventilated patients with PetCO2 monitoring to detect abnormalities and to analyse the reason / 中国基层医药

Objective To analyse the clinical situations and other factors that influence the PetCO2 monito-ring. The analysis can improve the nursing care for mechanical ventilated patients. Methods To retrospectively ana-lyze 212 PetCO2 monitoring ntanbers and capnograms in 108 mechanical ventilated patients. Results PetCO2 abnor-malities rate was 13.4%; leakage in the ventilator system was 30.4%; endotracheal tube malposition 6.8%; endo-tracheal tube baloon leakage 11.3%; secreations 22.4%; hyperventilation 12.5%; hypopeffusion 7.6%; hypoper-fusion of the lung 5.8%; mechanical malfunctioning 3.2%. Conclusions Continue monitoring of PetCO2 and cap-nogram along with hemodynamic monitoring in mechanical ventilated patients can timely find patients' problems and promptly use appropriate interventions. The understanding of these monitoring systems can improve the quality of the nursing care for the critically ill patients.

Management of acute infusion reactions associated with cetuximab therapy in clinic / 肿瘤

Objective: To describe the clinical consequences of acute infusion reactions associated with cetuximab treatment and analyze corresponding managing experience to explore the prevention and treatment approaches. Methods: Clinic staff identified 24 patients with advanced gastric cancer and colorectal cancer who had received chemotherapy combined with cetuximab treatment and experienced an acute infusion reaction. Their clinical manifestation and infusion reaction management procedures were retrospectively analyzed. Results: Acute infusion reactions at grade I - II were observed in 4 of 24 cases (16.7%), occurring during the first 5-10 min after the first administration of cetuximab. Patients complained chills, chest tightness, and low fever (37-38.5°C) after 0.5 h infusion. The symptoms were self relieved after 1-2 h. When cetuximab was recharged at reduced infusion rate and with close monitoring, no acute infusion reactions were observed in the 4 patients. Conclusion: Discontinuation of cetuximab therapy is not necessary for the patients who experienced grade I - II infusion reaction mild-to-moderate reactions can be managed by reduction of the infusion rate and close observation of the symptoms. Patients who experienced grade III or IV infusion reactions may require permanent discontinuation of cetuximab therapy.

MRSA INFECTION IN INTENSIVE CARE UNIT: A REPORT OF 6 CASES / 解放军医学杂志

Objective To explore the strategies of prevention and treatment of MRSA infection in ICU patients. Methods The clinical data of 6 patients with MRSA infection occurring at the same time in ICU were reviewed retrospectively. Results Vancomycin was given in 4 cases, 250mg twice daily, and teicoplanin was given in one case, 400mg once daily. MRSA cultures were negative in 5 cases after antibiotic treatment. Conclusions MRSA infection occurs frequently in ICU patients, and it spreads readily. Antibiotic treatment, isolation and bacteriological monitoring are very important measures for control of MRSA infection in ICU patients. [HS(1*2/3]

The application of nutrition support in critical ill patients / 解放军医学杂志

Objective To evaluate the efficiency of nutrition support in critical ill patients. Methods A retrospective analysis was made to the efficiency of the nutrition support applied to 233 critical ill patients PN+EEN→EN+per os→per os was employed as the model of nutrition support, and a nasal feeding pump was used for enteral nutrition. Results During the period of nutrition support, in the 233 patients, 26 dead, the mortality was 11.16%. Early enteral nutrition significantly decrease the mortality in critical ill patients. There existed significant differences in complications in three kinds of enteral nutrition may methods. Conclusion It is feasible to give the critical ill patients, it might help to reduced the mortality in ICU patients.