ABSTRACT
Cutaneous leiomyosarcoma is a rare soft tissue tumor that accounts for 2~3% of all soft tissue sarcomas. Cutaneous leiomyosarcoma can be subdivided into dermal, subcutaneous, and secondary leiomyosarcomas. This subdivision is important because of the different prognosis according to the types. The dermal type of cutaneous leiomyosarcomas are small and grow in the dermis. They rarely metasize, and the prognosis for survival after excision is favorable. We describe a case of dermal type cutaneous leiomyosarcoma on the extensor surface of the right thigh in a 35-year-old man.
Subject(s)
Adult , Humans , Dermis , Leiomyosarcoma , Prognosis , Sarcoma , ThighABSTRACT
Cutaneous leiomyosarcoma is a rare soft-tissue tumor of smooth muscle derivation that accounts for 2%-3% of all soft tissue sarcomas. Cutaneous leiomyosarcomas can be subdivided into dermal and subcutaneous leiomyosarcomas. Because of the different prognosis, it is important to distinguish between dermal and subcutaneous forms. Immunohistochemical stains, such as vimentin, smooth muscle actin (SMA), desmin, CD68, CD34, and S-100, may aid in the recognition of smooth muscle derivation and in the differentiation from other malignant spindle cell tumors. We report a case of cutaneous leiomyosarcoma on the extensor surface of the left thigh in a 61-year-old man.
Subject(s)
Humans , Middle Aged , Actins , Coloring Agents , Desmin , Leiomyosarcoma , Muscle, Smooth , Prognosis , Sarcoma , Thigh , VimentinABSTRACT
Leiomyosarcoma is a relatively rare soft tissue sarcoma of smooth muscle derivation. Superficial or cutaneous leiomyosarcomas, which are very rare and account for less than 3% of the cutaneous soft tissue sarcoma, are subdivided into two groups; a dermal form and a subcutaneous form. Cutaneous leiomyosarcoma may occur anywhere on the body, but there is a predilection for the extremities, especially the thighs. However, leiomyosarcoma of the face is exceedingly rare. We present a case of cutaneous dermal leiomyosarcoma on the face.
Subject(s)
Extremities , Leiomyosarcoma , Muscle, Smooth , Sarcoma , ThighABSTRACT
Primary cutaneous leiomyosarcoma is a rare neoplasm. The tumor presents as a nondescript subcutaneous mass, and may be painful or tender. The diagnosis depends on the histopathologic findings. We report a case of primary cutaneous leiomyosarcoma developed in a 57-year-old male. Five and half years ago, the patient noticed a rice grain sized nodule on the right deltoid area. Five years ago, the lesion was excised at a local medical office. From 2 years ago, the tumor recurred on the excision site as a well defined painful erythematous hard tumor, measuring 3.5*3cm. Biopsy specimen showed densely packed, interlacing bundles of smooth muscle cells which have numerous anaplastic nuclei, atypical giant cells with bizarre nuclei and 10 mitotic figures per 10 high power fields.