ABSTRACT
Cyclodestruction is generally achieved by applying thermal energy across the intact sclera. Commonly employed modalities are ultrasound, cryopexy, diathermy, noncontact laser light and most recently, contact transscleral laser using argon, krypton and Nd:YAG, diode laser. This study was performed to compare the pressure lowering and tissue effects of contact transscleral cyclophotocoagulation(TSCPC) with diode laser using G prode to cyclocryotherapy in rabbit. The results of this study demonstrate a similar intraocular pressure lowering effect of both cyclocryotherapy and contact TSCPC with diode laser using G prode. Histologic studies showed that both TSCPC and cyclocryotherapy are effective anatomic cyclodetructive modalities but in case of TSCPC, less severe destruction of ciliary body was noted. This study indicated that contact TSCPC with diode laser using G probe delivery provieds effective and safe management for eyes with medically and surgically uncontrolled glaucoma compared to cyclocryotheraphy.