1.
Journal of International Oncology
;
(12): 115-117, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-466591
ABSTRACT
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 (DDX43) plays an important role in the malignant proliferation,drug resistance of tumor cells as well as neoplasm immunotherapy.The overexpression of DDX43 has been found in various solid tumors and some hematologic malignancies.The hypomethylation of DDX43 gene promoter is identified in chronic myeloid leukemia,acute myeloid leukemia and myelodysplastic syndrome,which is correlated with DDX43 overexpression and the prognosis of these diseases.