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Background@#Psoriasis vulgaris is a chronic immune-mediated inflammatory multi-system disease characterised by keratinocyte hyperproliferation. Data regarding patients’ disease severity, knowledge and quality of life (QOL) is important to optimize treatment strategies for psoriasis. This study aims to evaluate and investigate the relationship between disease severity, knowledge and QOL of patients with psoriasis. @*Methods@#A cross-sectional multicentre study utilizing a socio-demographic data collection form, Psoriasis Knowledge Assessment Questionnaire (PKAQ), Dermatology Life Quality Index (DLQI) and Psoriasis Area and Severity Index (PASI was conducted. Correlations between PKAQ, DLQI and PASI were analysed using Spearman’s test. @*Results@#A total of 114 subjects participated in this study. Majority of them had mild psoriasis (n=73, 64%) based on PASI. The mean score of PKAQ was fourteen out of a total possible score of twenty-five, whereas the DLQI had a non-parametric distribution with a median (interquartile range) of 7 (10). Most subjects (32.5%) stated that psoriasis had a ‘moderate effect’ on their QOL, while only 3.5% said that it had an ‘extremely large effect’ on their QOL. There was a statistically significant correlation between PASI and DLQI (rs = 0.264, p = 0.004), with higher PASI scores corresponding to higher DLQI scores. No statistically significant correlation was found between DLQI and PKAQ (rs = -0.048, p= 0.612), and between PASI and PKAQ (rs = 0.058, p= 0.542).@*Conclusion@#Impairment of QOL was positively associated with severity of psoriasis. However, there was no significant relationship between knowledge and quality of life, as well as between knowledge and psoriasis severity.
Subject(s)
Patient Acuity , Patient Health QuestionnaireABSTRACT
Background@#Psoriasis is a chronic immune-mediated, multisystem inflammatory skin disease that can profoundly impact the quality of life (QoL) of both patients and their families. This study aimed to analyse the impact of psoriasis on the QoL of patients’ family members and its association with anxiety and depression. @*Methods@#This was a cross-sectional study which had a total of 240 subjects (80 patients, 80 family members, and 80 healthy controls). The Dermatology Life Quality Index (DLQI) questionnaire was used to evaluate the QoL of patients, and the Family Dermatology Life Quality Index (FDLQI) questionnaire was used to assess the QoL of family members. In addition, the Hospital Anxiety and Depression Scale (HADS) was used to evaluate the state of anxiety or depression of all subjects, including the healthy controls.@*Results@#Up to 82.5% of family members of psoriasis patients had impaired QoL (FDLQI ≥2). The mean DLQI was 8.89±7.58, whereas the mean FDLQI scores was 7.58±6.09, showing the considerable impact of psoriasis on both patients and family members’ quality of life. There was a positive correlation between family members’ QoL with patients’ anxiety (rs =0.348; p=0.002) and depression (rs =0.276; p=0.013) level. However, no association was found between family members’ QoL with patients’ psoriasis severity (rs =0.173; p=0.126) and the DLQI scores (rs =0.137; p=0.224). Based on the HADS, the mean anxiety scores was 5.29±4.07 and the mean depression scores was 4.54±4.20 for family members. An anxiety disorder was suggested in 32.5%, while depression was suggested in 23.8% of family members.@*Conclusion@#Psoriasis has a significant impact on both patients and their family members, who experienced impairment of their QoL and higher levels of anxiety and depression.
Subject(s)
PsoriasisABSTRACT
Background: A huge number of patients in our country are affected by Tinea Corporis (TC). The number of patients affected by dermatophytosis has increased by a large extent in the last 4 to 5 years. The quality of life in TC patients can be affected by various factors including the disease morbidity, duration of disease, social & demographic factors. Aims and Objectives: The aim of the study is to find out the effect of TC on the quality of life of the affected patients & along with that to assess whether there is some association of this effect on quality of life with some demographic & clinical factors. Methods: The effect on quality of life of 328 patients affected by TC who attended the Dermatology outpatient’s department of NRS Medical College was assessed using the Dermatology Life Quality Index (DLQI) questionnaire. Results: 12 (3.658 %) of the patients had an extremely large effect on quality of life. There was a very large effect on the QOL of 121 (36.890 %) patients. There was moderate effect on 134 (40.853 %) of the patients. There was a small effect on 59 (17.987 %) of the patients. 2 (0.609 %) patients had no effect on their QOL. Duration of disease & body surface area involved have significant impacts on QOL. Conclusion: The quality of life is adversely affected by TC. Early detection & treatment of the disease is very important. Steps must be taken to increase awareness about the disease among the general population.
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Introduction: Patients reporting with skin ailments to primaryhealthcare settings are often referred to specialty centreseither due to uncertainty in diagnosing skin conditions by thehealthcare professionals or because of incomplete treatmentoffered to the patients at this level of healthcare. Objectives:1.To assess the quality of life among adults reporting withskin diseases to a Primary healthcare setting. 2.To identify thetypes of skin diseases that required referral to specialty clinics.Material and Methods: A cross-sectional study wasconducted at an Urban Health Centre in Goa between July2018 and September 2018 among 150 consenting patientsaged 18 years and above reporting with skin ailments. Datawere collected by administering a pre-tested semi-structuredquestionnaire and the Quality of Life was assessed using theDermatology Life Quality Index. Data was summarised usingfrequencies and percentages for demographic characteristics,The DLQI was scored as per the method recommended bythe developers. Chi-Square test was used to determine theassociation among study variables. A P<0.05 was consideredstatistically significant.Results: Mean DLQI score in this study was 6.67 ± 4.147indicating a small to moderate effect of skin diseases onpatient’s QoL. Mean DLQI score of Symptoms/Feelingsdomain was 2.94 ± 1.475 out of a maximum score of six,followed by domains like Daily activities (1.12 ± 1.197) andWork/School (1.06 ± 1.148) respectively.Conclusion: A small to moderate impact on QoL was observedamong patients with skin conditions. This study suggests aneed for special training in the management of common skindiseases for healthcare professionals at primary healthcaresettings, at the same time adding the necessary medicationsused for the treatment of these common skin conditions tothe inventory of essential drugs maintained at this level ofhealthcare.
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Objetivos: evaluar la utilidad práctica en nuestro medio del índice revisado de área y severidad del lupus cutáneo (RCLASI). Correlacionar RCLASI con DLQI (índice de calidad de vida dermatológico). Materiales y Métodos: estudio observacional, descriptivo y transversal realizado en el Hospital General de Agudos José María Ramos Mejía, Ciudad Autónoma de Buenos Aires - Argentina - por dos grupos de observadores divididos según nivel de experiencia en dermatología. Se realizó RCLASI Y DLQI en 12 pacientes con Lupus Eritematoso Cutáneo (LEC). Se evaluó en RCLASI el tiempo requerido, la variabilidad inter-observador y la dificultad del método. Resultados: la media de actividad para el grupo de baja experiencia fue de 11,8 puntos (SD 8,1) y para el de moderada / alta experiencia 12,7 (SD 8). La media de daño para el primer grupo fue 4 (SD 4,7) y para el segundo 4,4 puntos (SD 5,4), respectivamente. El tiempo promedio para ambos grupos fue de 7,76 minutos, siendo para el grupo de baja experiencia 9,79 y para el de moderada / alta 5,73. El método resultó fácil en más del 50% de los casos, independientemente del nivel de experiencia. El 50% de los pacientes no mostró efecto sobre la calidad de vida, 16,5% pequeño efecto, 25% moderado efecto y 8,5% gran efecto. Conclusión: el RCLASI es un método práctico y útil para evaluar todas las formas de LEC. Resulta fácil y expeditivo, pero carece de escala de severidad, lo que fue una limitante para compararlo con DLQI.
Objectives: to assess the practical utility of Revised Cutaneous Lupus Erythematosus Disease Area and Severity Index (RCLASI) in our population. To correlate: RCLASI with DLQI (Dermatology Life Quality Index). Materials and Methods: observational, descriptive and transversal study that was performed in Hospital General de Agudos José María Ramos Mejía, Ciudad Autónoma de Buenos Aires - Argentina - by two groups of observers divided by their level of experience in dermatology. RCLASI and DLQI were assessed in 12 patients with Cutaneous Lupus Erythematosus (CLE). Time spent, inter observer variability and method´s levels of difficulty were evaluated. Results: the mean activity score for the group of low experience was 11,8 (SD 8,1) and for the group of moderate / high experience 12,7 (SD 8). The mean damage score for the former was 4 (SD 4,79) and for the later 4,4 (SD 5,4). The mean time spent by both groups was 7,76 minutes (9,79 minutes mean by the group of low experience and 5,73 by the group of moderate / high experience). The method was considered easy in more than 50% of the cases, independently of the observers´s level of experience. 50% of the patients did not show effect in their quality of life whereas 16,5% showed little effect, 25% mild effect, and 8,5% big effect. Conclusions: RCLASI is a useful and feasible method to evaluate all types of CLE. It’s easy and rapid, however it lacks a severity scale. This later limited its comparison with DLQI.
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Objective To investigate the safety and effectiveness of compound card force cumin tincture in the treatment of vitiligo .Methods The 86 cases of vitiligo patients included in the study were randomly divided into two groups,observation group(n=43) and control group(n=43).The observation group was given narrow-band ul-traviolet B irradiation and compound card force cumin tincture ,and the control group was only given narrow-band ul-traviolet B irradiation .The clinical efficacy and the dermatology life quality index ( DLQI) in two groups were observed and compared.Results The total efficiency rate after 1st,2nd,3rd course of treatment in the observation group were higher than those of the control group ,and the total efficiency rate after 3rd course of treatment in the observation group was significantly higher than that of the control group (χ2 =4.568,P0.05).Conclusion Compound card force cumin tincture in the treatment of vitiligo has more clinical superiority .
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BACKGROUND: Evidence for superior outcome by adhering to therapy guidelines is imperative to their acceptance and adaptation for the optimal management of disease variants. OBJECTIVE: Comparative study of prospective outcomes in simultaneous consideration of independent variables in groups of 150 patients of plaque psoriasis either treated adhering to or in digression of standard guidelines. METHODS: The psoriasis area severity index (PASI) and the dermatology life quality index (DLQI), prior to and after three months of uninterrupted therapy were examined in treatment groups among 150 patients. Recovery rates of 75% or more in PASI were compared. Independent variables were also examined for their bearing on the outcome. RESULTS: The vast majority was early onset disease phenotype. All three treatment regimens when administered in adherence to the guidelines yielded significantly superior rates of defined recovery both in PASI and DLQI. Compromise of the therapeutic outcome appeared in high stress profiles, obesity, female sex and alcohol, tobacco or smoking habit. CONCLUSION: Conventional drug therapy of plaque psoriasis yields superior outcome by adhering to the consensus guidelines. Psychiatric address to stress must be integral and special considerations for phenotypic/syndromic variants is emphasized for effective therapy of psoriasis.
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Female , Humans , Consensus , Dermatology , Obesity , Phenotype , Prospective Studies , Psoriasis , Quality of Life , Smoke , Smoking , Nicotiana , UrsidaeABSTRACT
Objectives To determine the socio-demographic profile, clinical characteristics and quality of life of adult psoriasis patients as well as the association between the first two variables with the latter. Methods A cross-sectional study of 30 adult psoriasis patients was conducted in the Dermatology Clinic, Serdang Hospital from 9th to 23rd May 2011. A questionnaire regarding clinical data containing multilingual Dermatology Life Quality Index (DLQI) was used in a face-to-face interview. Results Male-to-female ratio was 1:1.5. Psoriasis was more common in Malays (76.7%) compared to Chinese (10%) and Indians (10%), however this ethnic distribution was proportionate to that of the clinic attendance. The onset of psoriasis was during the second to third decade of life in most patients (53.3%) with a mean of 31 years (range 7 - 62). Nine (30%) patients had positive family history of psoriasis. The main aggravating factors were stress and sunlight. Hyperlipidemia was the commonest associated co-morbidity. Plaque psoriasis was the commonest clinical type (66.7%) and majority (66.7%) had <10% body surface area affected. Nail changes were present in 15 (50%) patients and psoriatic arthropathy occurred in 11 (36.7%), with mono/oligoarticular type being as common as symmetrical polyarthropathy. All patients were treated with topical therapy, six were on systemic medication and only one underwent phototherapy. The mean DLQI score was 10.77 ± 6.22. The duration of disease and the age group were negatively correlated with the DLQI scores (r= -0.45 and -0.42 respectively, p < 0.05). Conclusion The clinical findings are similar to previous local studies and are valuable to improve patient care.
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BACKGROUND: The symptoms of atopic dermatitis (AD) may lead to the impairment of overall quality of life (QOL). Many international studies have addressed the effects of AD on the QOL of patients and their families'. However, studies from Korea are few and insufficient. OBJECTIVE: The purpose of this study was to identify the correlation between the QOL and clinical disease severity in adults with AD. METHODS: Thirty-one AD patients ranging in age from 19~43 years were included. Dermatology Life Quality Index (DLQI) and the shorter version of World Health Organization QOL assessment instrument (WHOQOL-BREF) were used to determine the QOL. Eczema area and severity index (EASI) was examined to evaluate the severity of AD. RESULTS: The mean DLQI, QOL and EASI score was 19.74+/-6.93, 3.77+/-0.76 and 9.42+/-11.12, respectively. DLQI and QOL scores significantly correlated with EASI score (p0.05). Each domain of the WHOQOL-BREF and EASI score did not show meaningful correlation (p>0.05). However, for DLQI, categories of emotion, daily life, work and school work showed a high correlation with the EASI score (all p<0.05). Both DLQI and QOL score showed significant correlation with the EASI score in females (p<0.05), but only QOL score showed high correlation in male (p<0.05). CONCLUSION: AD affects QOL of adults with AD as the disease severity increases. In managing the AD patients, evaluating the clinical severity and evaluating QOL of patients would be necessary and emotional support will be helpful.
Subject(s)
Adult , Female , Humans , Male , Dermatitis, Atopic , Dermatology , Eczema , Korea , Quality of Life , World Health OrganizationABSTRACT
Atopic dermatitis is influenced by numerous environmental factors, as well as various hereditary factors. This variety of factors makes therapy difficult, and necessitates treatment on an individual, case-by-case basis.<br>We report the case of a 21-year old woman with atopic dermatitis. The patient underwent acupuncture 11 times, in accordance with traditional Chinese medicine theory, in addition to her medicaments. This treatment resulted in improvement of her skin eruptions, QOL, IgE-RIST and eosinophils. This may demonstrate that concomitant use of acupuncture therapy is effective in the improvement of atopic dermatitis.