ABSTRACT
Objective To study the causes and methods of prevention and treatment of severe acute pancreatitis (SAP) complicated with postoperative duodenal fistula. Methods Twenty-two cases with severe acute (pancreatitis) complicated with postoperative duodenal fistula were retrospectively analyzed . Results Among 184 patients with severe acute pancreatitis undergoing operative treatment,duodenal fistula developed in 22 (patients),and in 15 of the 22 (patients), it occurred 2 weeks after operation.In 18 patients the duodenal fistula healed spontaneously with conservative therapy and 4 patients were cured by re-operation. Conclusions (Duodenal) fistula is related to early operation for SAP,peripancreatic infection,and improper placement of (drainage) tube at time of operation or (prolonged) (placement) of (drainage) tube.Most duodenal fistulas can be (spontaneously) cured by maintaining patent drainage around the fistula, actively controlling peripancreatic (infection), suppression of gastrointestinal secretion, and augmention of nutritional support.