Condición física e inflamatoria antes de una intervención quirúrgica mayor abdominal / Physical and inflammatory condition before major abdominal quirurgical intervention

Introducción: El desacondicionamiento físico se asocia con disminución en la capacidad cardiorrespiratoria, aumento en el contenido de grasa corporal, e imbalances en respuesta inflamatoria, todos ellos factor de riesgo frente a la agresión de una intervención quirúrgica mayor. El valor de consumo de oxígeno (VO2max), el índice de masa corporal (IMC) y los valores plasmáticos de citoquinas de pacientes programados para una intervención quirúrgica mayor abdominal a menudo no se tienen en cuenta en la valoración prequirúrgica. Objetivo: Determinar la condición física e inflamatoria de pacientes que se trataron con una intervención quirúrgica mayor abdominal. Métodos: Investigación cuantitativa, descriptiva. Muestra por conveniencia de pacientes que se trataron con una intervención quirúrgica mayor abdominal en dos hospitales de Manizales (Colombia). Previo a la intervención, se midió VO2max, el IMC y valores de citoquinas. Resultados: Participaron en el estudio 6 hombres y 48 mujeres. Los valores promedio del VO2max se categorizaron como bajos. Se encontraron valores altos de IMC, del receptor antagonista de IL-1 (IL-1 Ra) y del factor neutrotrófico derivado del cerebro (BDNF). No se hallaron diferencias significativas en los valores promedio de VO2max, de IL-1Ra y de BDNF entre los grupos. Los pacientes programados para intervención quirúrgica ginecológica y gastrointestinal tuvieron sobrepeso y los programados para intervención quirúrgica bariátrica fueron obesos mórbidos. Conclusión: Pacientes programados para una intervención quirúrgica mayor abdominal presentan valores bajos de VO2max para la edad y altos de IMC. Se hallaron valores altos de IL-1Ra y de BDNF asociadas a obesidad y a posible antiinflamación(AU)

Introduction: Physical deconditioning is associated with, a decrease in cardiorespiratory capacity, an increase in body fat content and imbalances in the inflammatory response, all of which are risk factors for the aggression of a major surgical intervention. The oxygen consumption value (VO2max), body mass index (BMI), and plasma cytokine values of patients scheduled for major abdominal surgery are often not taken into account in the presurgical evaluation. Objective: To determine the physical and inflammatory condition of patients who were treated with a major abdominal surgery. Methods: Quantitative, descriptive research. Convenience sample of patients who underwent major abdominal surgery in two hospitals in Manizales (Colombia). Prior to the intervention, VO2max, BMI and cytokine values were measured. Results: 6 men and 48 women participated in the study. Average VO2max values were categorized as low. High values of BMI, IL-1 receptor antagonist (IL-1 Ra) and brain derived neutrotrophic factor (BDNF) were found. No significant differences were found in the mean VO2max, IL-1Ra and BDNF values between the groups. Patients scheduled for gynecological and gastrointestinal surgery were overweight and those scheduled for bariatric surgery were morbidly obese. Conclusion: Patients scheduled for major abdominal surgery have low VO2max values for age and high BMI. High IL-1Ra and BDNF values were found associated with obesity and possible anti-inflammation(AU)

Fluid and hemodynamic management in hemodialysis patients: challenges and opportunities / Manejo hídrico e hemodinâmico em pacientes em hemodiálise: desafios e oportunidades

Abstract Fluid volume and hemodynamic management in hemodialysis patients is an essential component of dialysis adequacy. Restoring salt and water homeostasis in hemodialysis patients has been a permanent quest by nephrologists summarized by the 'dry weight' probing approach. Although this clinical approach has been associated with benefits on cardiovascular outcome, it is now challenged by recent studies showing that intensity or aggressiveness to remove fluid during intermittent dialysis is associated with cardiovascular stress and potential organ damage. A more precise approach is required to improve cardiovascular outcome in this high-risk population. Fluid status assessment and monitoring rely on four components: clinical assessment, non-invasive instrumental tools (e.g., US, bioimpedance, blood volume monitoring), cardiac biomarkers (e.g. natriuretic peptides), and algorithm and sodium modeling to estimate mass transfer. Optimal management of fluid and sodium imbalance in dialysis patients consist in adjusting salt and fluid removal by dialysis (ultrafiltration, dialysate sodium) and by restricting salt intake and fluid gain between dialysis sessions. Modern technology using biosensors and feedback control tools embarked on dialysis machine, with sophisticated analytics will provide direct handling of sodium and water in a more precise and personalized way. It is envisaged in the near future that these tools will support physician decision making with high potential of improving cardiovascular outcome.

Resumo O volume de fluidos e o controle hemodinâmico em pacientes em hemodiálise é um componente essencial da adequação da diálise. A restauração da homeostase do sal e da água em pacientes em hemodiálise tem sido uma busca constante por parte dos nefrologistas, no que condiz à abordagem do "peso seco. Embora essa abordagem clínica tenha sido associada a benefícios no desfecho cardiovascular, recentemente tem sido questionada por estudos que mostram que a intensidade ou agressividade para remover fluidos durante a diálise intermitente está associada a estresse cardiovascular e dano potencial a órgãos.para remover fluidos durante a diálise intermitente está associada a estresse cardiovascular e dano potencial a órgãos. Uma abordagem mais precisa é necessária para melhorar o desfecho cardiovascular nessa população de alto risco. A avaliação e monitorização do estado hídrico baseiam-se em quatro componentes: avaliação clínica, ferramentas instrumentais não invasivas (por exemplo, US, bioimpedância, monitorização do volume sanguíneo), biomarcadores cardíacos (e.g. peptídeos natriuréticos), algoritmos e modelagem de sódio para estimar a transferência de massa. O manejo otimizado do desequilíbrio hídrico e de sódio em pacientes dialíticos consiste em ajustar a remoção de sal e líquido por diálise (ultrafiltração, dialisato de sódio), e restringir a ingestão de sal e o ganho de líquido entre as sessões de diálise. Tecnologia moderna que utiliza biosensores e ferramentas de controle de feedback, hoje parte da máquina de diálise, com análises sofisticadas, proporcionam o manejo direto sobre o sódio e a água de uma maneira mais precisa e personalizada. Prevê-se no futuro próximo que essas ferramentas poderão auxiliar na tomada de decisão do médico, com alto potencial para melhorar o resultado cardiovascular.

Acción de los fisioterapeutas en situaciones de desacondicionamiento en unidades de cuidado intensivo / Action of physiotherapists in deconditioning in intensive care units

El desacondicionamiento físico es una situación de pérdida de condiciones fisiológicas y meta- bólicas de diversos sistemas ocasionada por la permanencia en reposo, afecta los desempeños y posibilidades funcionales de la persona, y se presenta de manera frecuente en personas en Unidades de Cuidado Intensivo (UCI). En dicho contexto se puede intervenir por programas de acción Fisioterapéutica. Objetivo: Revisar en la literatura reciente los aspectos que orientan la in- tervención del Fisioterapeuta en situaciones de desacondicionamiento en Unidades de Cuidado Intensivo. Método: Se realizó un estudio de revisión, de alcance descriptivo, a partir de consultas en bases de datos entre junio de 2014 y febrero de 2015 con artículos de texto completo. Resulta- dos: Se encontraron 32 artículos que cumplieron los criterios de inclusión y de ellos el 53% corres- pondieron a estudios de carácter experimental. Los enfoques de intervención se concentraron en estrategias dirigidas al entrenamiento de la capacidad aeróbica , la fuerza y resistencia muscular, el 25% de los artículos mostraron que pacientes que se intervenían Fisioterapéuticamente en Cuidados Intensivos tenían una mejoría significativa en la función pulmonar, el rendimiento muscular y en particular en el entrenamiento efectivo de la fuerza explosiva. Conclusiones: Pro- ducto de la revisión adelantada se encuentra que las intervenciones tempranas realizadas por profesionales en Fisioterapia permiten revertir las complicaciones generadas por la inmovilidad prolongada y estas se deben instaurar en las primeras 24 horas de internación del paciente.

Physical deconditioning is a physiological and metabolic loss of conditions that affects various systems due to the permanence of a person at rest. It affects their performance and functional possibilities and it is commonly found in intensive care units (ICU). In this context, this situation could be intervened with programs of physiotherapy action. Objective: to review the in recent lite- rature the guidance elements for interventions made by Physiotherapists in situations of decondi- tioning in intensive care units. Method: A document review research was made, with a descriptive range, by consulting databases between June 2014 and February 2015. Results: In the research, 32 articles that met the inclusion criteria were found and 53% of them were experimental studies. In- tervention approaches focused on strategies aimed at training aerobic capacity, muscular strength and endurance, 25% of these articles showed that patients who were involved of Physical Therapy in intensive care units had a significant improvement in lung function, muscle performance and particularly in the effective training of the explosive force. Conclusions: The research showed that early interventions made by professionals in Physiotherapy can reverse the complications caused by prolonged immobility and these should be implemented during the first 24 hours after the ad- mission of the patient.

Using the SBAR4 model for Management of a Patient with Complex Comorbidites in the Nursing home - A case study

Singapore faces a rapidly ageing population. By 2030, 19 percent of the population will be aged 65 years and older. The rise of the dual-income family, the decline of extended families, as well as the increase in age-related degenerative disorders consequent to increased expectancy of life, create challenging situations. Families which are manpower and expertise challenged will find it difficult to look after their elderly infirm at home, especially if the elderly members are frail, functionally dependent, and prone to falls. Such families will increasingly look to the nursing home as solutions. To aid in allocation to nursing homes, elderly patients are classified into 4 categories by the Resident Assessment Form: Category I patients are physically and mentally independent; Category II patients are semi-ambulant; Category III patients are wheelchair-bound or bed-bound; and Category IV are highly dependent. Categories I and II are primarily admitted to sheltered homes, while the limited nursing home places are mainly reserved for Category III and IV patients. The SBAR4 Tool is useful for clerking nursing home placement applications for placement decisions; for admission clerking; and for follow-up assessments and interventions. A case study of a patient who became bed-bound after hospitalisation for pneumonia due to deconditioning is used to illustrate the use of the SBAR4 Tool in a patient admitted to a nursing home, in implementation of recommendations, and in follow-up review of this patient a year later.

The Role of Rehabilitation Medicine in Large-scale Disasters / The Japanese Journal of Rehabilitation Medicine

In recent decades, natural disasters have increased markedly. A large-scale disaster can cause not only severe injuries but also stress-related diseases such as cardiovascular events. Particularly, the elderly and persons with preexisting disabilities are at greater risk for injuries, worsening disabilities and deaths in a disaster. The Great East Japan Earthquake 2011 revealed that rehabilitation medicine had some essential roles for people requiring assistance in a large-scale disaster. Firstly, in the acute phase immediately after the disaster, it was important to protect elderly and disabled people from dangerous situations. In this instance, even though significant numbers of vulnerable people requiring assistance remained in the affected area, there were insufficient sheltered locations available, because a large number of medical and welfare facilities were destroyed. Secondly, in the post acute phase after the earthquake, the medical rehabilitation needs for disaster-related disease such as cerebrovascular accidents increased. Finally, in the chronic phase of the disaster, the community based rehabilitation needs to prevent deconditioning syndrome had gradually grown. The aging of the Japanese population is a crucial issue. In this regard, disaster rehabilitation for vulnerable people is similar to comprehensive community care in many aspects. To support disaster victims, the Disaster Acute Rehabilitation Team (DART) and the Japan Rehabilitation Assistance Team (JART) have been proposed to take the lead in disaster rehabilitation. To support these and other ongoing efforts and to better prepare for the future, the Japanese Association of Rehabilitation Medicine and other related rehabilitation professional societies should provide specialized training on disaster rehabilitation.

Rehabilitation for Patients Recovering from Threatened Abortion and Premature Labor : During Pregnancy and the Postpartum Period / The Japanese Journal of Rehabilitation Medicine

Bed rest for pregnant women recovering from threatened abortion and premature labor to prevent abortion can cause deconditioning syndrome, but it is not clear what kind of physical exercise should be provided for these patients. To better provide appropriate rehabilitation for threatened abortion and premature labor patients, we investigated patient clinical records retrospectively. In 11 patients who were provided rehabilitation within the past three years, eight delivered during hospitalization and three became independent in ADLs and were discharged while still pregnant. All patients who delivered during their hospitalization became independent in ADLs immediately after delivery, and as a result, the maternal prognosis was good. Choosing an appropriate rehabilitation approach for patients with threatened premature labor may help alleviate their deconditioning during pregnancy without any adverse impact.

Association of Nutrition Status and Rehabilitation Outcome in the Disuse Syndrome: a Retrospective Cohort Study / General Medicine

<b>Background:</b> To determine whether nutrition is associated with rehabilitation outcome in the disuse syndrome.<br><b>Methods:</b> A retrospective cohort study was performed in 223 inpatients admitted to a university hospital who were diagnosed by physicians in the rehabilitation department as having the disuse syndrome, and subsequently prescribed physical therapy. Malnutrition was defined as a body mass index<18.5 kg/m², hemoglobin level<10.0 g/dl, serum albumin level<3.0 g/dl, or total lymphocyte count<1200 cells/mm³. Rehabilitation outcome was defined as whether or not the ADL score improved during rehabilitation. Nutritional status was assessed at referral using the Onodera's prognostic nutritional index (PNI).<br><b>Results:</b> The study cohort included 136 men and 87 women (mean age 67.5 years; median duration between admission and referral 17 days; median rehabilitation duration 32 days). A total of 202 patients (91%) were defined as being malnourished. Mean PNI was 32.9, with the ADL score improving in 135 patients (61%) during rehabilitation. Rehabilitation outcome was better in patients with normal nutrition compared to malnourished patients (relative risk: 0.72, p=0.04). Patients with a hemoglobin level>10.0 g/dl (relative risk: 0.69, p=0.001), total lymphocyte count>1200 cells/mm³ (relative risk: 0.78, p=0.03), or PNI>35.0 (relative risk: 0.74, p=0.01) had a better rehabilitation outcome. Logistic regression analysis showed that hemoglobin level was associated independently with rehabilitation outcome (odds ratio 2.34, p=0.005).<br><b>Conclusions:</b> Malnutrition is common in patients with the disuse syndrome. Patients with low hemoglobin level and PNI at referral are more likely to have a poor rehabilitation outcome.

Cardiovascular behavior during rehabilitation after coronary artery bypass grafting / Comportamento cardiovascular durante a reabilitação após cirurgia de revascularização do miocárdio

OBJECTIVE: The aim of the present study was to assess the behavior of cardiovascular variables during an in-hospital cardiovascular rehabilitation program in patients following myocardial revascularization surgery. METHODS: A total of 14 patients (mean age: 55.4 ± 6.4 years, 78.6 percent male) participated in the study, all of whom had a previous diagnosis of coronary insufficiency and indication for elective surgery. The protocol consisted of a group of low-impact (2-3 METs) upper/lower extremity and walking exercises performed both pre and post-operatively (3rd and 4th days). The following variables were evaluated at rest and following the exercise program: heart rate (HR, bpm); systolic arterial pressure (SAP, mmHg); diastolic arterial pressure (DAP, mmHg); mean arterial pressure (MAP, mmHg); double product (DPr, bpm/mmHg); and the Rating of Perceived Exertion (RPE) scale. RESULTS: There was a significant increase in HR and DPr in the individual analysis (P<0.001) as well as in between days (P<0.001 for HR and P<0.05 for DPr), but only attaining maximal values that were < 30 percent of predicted. Moreover, a negative correlation was found between the RPE scale and both SAP and MAP. CONCLUSION: The exercises proposed proved to be safe with the change in key physiologic variables throughout the experiment below recommended values for the hospitalization phase. Furthermore, the RPE scale appears to have a correlation with some hemodynamic variables and thus may be a useful tool for this group of patients.

OBJETIVO: O objetivo do presente estudo foi avaliar o comportamento das variáveis cardiovasculares durante um programa de reabilitação cardiovascular hospitalar em pacientes submetidos à cirurgia de revascularização do miocárdio. MÉTODOS: Um total de 14 pacientes (idade média: 55,4 ± 6,4 anos, 78,6 por cento do sexo masculino) participaram do estudo, todos apresentavam diagnóstico prévio de insuficiência coronariana e indicação de cirurgia eletiva. O protocolo consistiu de um grupo de exercícios de baixo impacto (2-3 METs) para extremidade superior e inferior e exercícios de caminhada realizados no pré e pós-operatório (3 e 4 dias). As seguintes variáveis foram avaliadas em repouso e após o programa de exercício: frequência cardíaca (FC, bpm), pressão arterial sistólica (PAS, mmHg), pressão arterial diastólica (PAD, mmHg), pressão arterial média (MAP,mmHg), duplo produto (DPr, bpm/mmHg) e escala de Índice de Percepção de Esforço (IPE). RESULTADOS: Houve aumento significativo da FC e DPr na análise individual (P <0,001), bem como na análise entre os dias de avaliação (P <0,001 para FC e P <0,05 para DPr), mas apenas atingindo valores máximos que foram < 30 por cento do previsto. Além disso, ocorreu correlação negativa entre a escala IPE e SAP e MAP. CONCLUSÃO: Os exercícios propostos mostraram-se seguros com a mudança de variáveis fisiológicas fundamentais em todo o experimento abaixo do valor recomendado para a fase de hospitalização. Além disso, a escala percepção de esforço parece ter correlação com algumas variáveis hemodinâmicas e, portanto, pode ser uma ferramenta útil para este grupo de pacientes.

Effect of microgravity on biological characteristics of vascular endothelial cell / 国际生物医学工程杂志

Under the condition of microgravity, human body will experience a series of cardiovascular deconditioning. The vascular endothelial cells are the most important component of the vessel wall, so the changes of biological characteristics of vascular endothelial cells are directly related to cardiovascular deconditioning. Therefore, it is important to prevent and treat the cardiovascular deconditioning in astronauts by studying the effect of microgravity on biological characteristics of vascular endothelial cells.

The Effects of Regular Walking Exercise on Metabolic Syndrome, Cardiovascular Risk Factors, and Depressive Symptoms in the Elderly with Diabetic Mellitus

PURPOSE: This study aimed to estimate the effects of a regular walking exercise program on metabolic syndrome, cardiovascular risk factors, and depressive symptoms among the elderly with diabetic mellitus (DM) based on the Theory of Reasoned Action (TRA). METHODS: This study has randomized and stratified experimental design with experimental and control groups. We developed a regular walking exercise program suitable for the elderly with DM based on the guidance of AAHPERD. The experimental group participated in the regular walking exercise program, which contains walking exercise 3 times a week and 50 minutes each time for 3 months and education on controlling diet and preventing complications once a week and 20 minutes each time for 4 weeks. Post-test was conducted after 3 months to estimate metabolic syndrome, cardiovascular risk factors, and depressive symptoms. RESULTS: The regular walking exercise program was effective for decreasing the waist size, the level of fasting blood glucose (FBG) and triglyceride (TG), cardiovascular risk factors and the severity of depressive symptoms among the elderly with DM. CONCLUSION: The incidence of complications would be decreased by applying a regular walking exercise program.

Concept Analysis: Deconditioning / 재활간호학회지

PURPOSE: The purpose of this study was to explore the concept of deconditioning within the field of nursing allied health sciences. METHOD: The concept analysis method described by Walker and Avant(1995) was used. Critical attributes, antecedents, consequences, and empirical referents were identified. Also model, borderline, contrary and related cases were proposed. RESULTS: The definition of concept 'deconditioning' was a decrease in the function of general system that occured after long periods of immobility and might be marked by frail upon return to normal conditions. The attributes of deconditioning were as follows; 1) the deconditioning was caused by lengthening of physical inactivity; 2) the deconditioning state was resulted by respiratory system, cardiovascular system, musculoskeletal system, hematologic system and generalized manifestation; 3) the deconditioning state could be reconditioned. 4) The reinforced functions by exercise could be compromised by physical inactivity. CONCLUSION: Deconditioning is important concept in nursing practice since it occurs commonly in any patients who lack physical activity for long time and affects many aspects of clinical outcomes, but it could be reversible by nurses' efforts.