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Audiol., Commun. res ; 19(1): 88-94, 03/2014. tab, graf
Article in Portuguese | LILACS | ID: lil-705735

ABSTRACT

Objetivo : Avaliar os efeitos da Levodopa na deglutição de pacientes com Doença de Parkinson (DP). Métodos : O estudo foi realizado no Programa Pró-Parkinson do Hospital das Clínicas da Universidade Federal de Pernambuco. Foram estudados 20 pacientes com DP idiopática e 12 sujeitos normais (grupo controle). A eletromiografia de superfície (EMGs) foi registrada sobre a musculatura supra-hióidea, durante a deglutição de 3 ml e 10 ml de água e iogurte. Cada volume foi repetido cinco vezes. Esse protocolo foi realizado no grupo com DP antes e após a medicação, período off e on, e no grupo controle, uma única vez. Resultados : A amplitude das EMGs foi significativamente maior nos sujeitos do grupo controle do que nos pacientes com DP (off), na deglutição de cada volume de água. A duração das EMGs foi significativamente maior na deglutição de 3 ml de água e iogurte em pacientes com DP (off). Durante a fase on, diferenças significativas não foram notadas. Conclusão : A administração de Levodopa em pacientes com DP parece influenciar a amplitude e duração da EMGs dos músculos supra-hióideos, aproximando as variáveis aos valores de normalidade. .


Purpose : To evaluate the effects of Levodopa on the swallowing of patients with Parkinson’s Disease (PD). Methods : The study was carried out in the Pro-Parkinson Program of the Hospital das Clinicas of the Federal University of Pernambuco. Twenty patients with idiopathic PD and 12 normal subjects (control group) were studied. The surface Electromyography (sEMG) was recorded over the suprahyoid musculature during swallowing of 3 ml and 10 ml of water and yogurt. Each volume was repeated five times. This protocol was carried out on the group with PD before and after the medication, off and on periods, and on the control group, a single time. Results : The amplitude of the sEMG was significantly greater for subjects of the control group than for the patients with PD (off), regarding swallowing of each volume of water. The duration of the sEMG was significantly greater for the swallowing of 3 ml of water and yogurt in patients with PD (off). During the on phase, no significant differences were noted. Conclusion : The administration of Levodopa on patients with PD seems to influence the amplitude and duration of the sEMG of suprahyoid muscles, approximating the variables to the values of normalcy. .


Subject(s)
Humans , Deglutition Disorders , Electromyography , Levodopa/therapeutic use , Parkinson Disease/drug therapy , Cross-Sectional Studies , Health Programs and Plans
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