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Objective To analyze the correlation between tortuosity and stenosis in patients with myocardial bridge(MB)on the left anterior descending artery(LAD). Methods Data of patients with MB on the LAD,which was discovered by coronary computed tomography angiography(CCTA),in the Affiliated Hospital of North China University of Science and Technology from October 2015 to December 2018 were retrospectively analyzed.Among them 278 patients with tortuosity on LAD and 278 patients without tortuosity were selected.The clinical charateristics(age,gender,hypertension,hyperlipidemia,diabetes,smoking history,and family history)as well as the incidence and severity of stenosis of LAD were recorded and compared. Results The incidence of coronary artery stenosis in the non-tortuosity group(57.6%)was significantly lower than that in the tortuosity group(71.9%)($\bar{χ}$=12.608,
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Humans , China , Constriction, Pathologic , Coronary Angiography , Coronary Stenosis/epidemiology , Coronary Vessels/diagnostic imaging , Myocardial Bridging/pathology , Retrospective StudiesABSTRACT
Objective: To investigate the correlation of Apo-A and Apo-B/Apo-A ratio with the degree of coronary artery stenosis (CHD) in patients with coronary heart disease. Methods: Totally 234 patients with coronary heart disease examined with coronary angiography were collected. We collected blood lipid and calculated blood lipid ratio, such as non-HDL-C, TG/HDL-C, TC/HDL-C, LDL-C/HDL-C, and Apo-B/Apo-A. Gensini score was calculated according to the result of CAG. We analyzed the correlation between the blood lipid indicators and the Gensini score with the Spearman correlation analysis. Linear regression analysis was made of the correlation between those meaningful indicators and the Gensini score. Results: There were no significant differences in age, hypertension, diabetes or smoking index between all Gensini score groups. The illness course in middle-score group was longer than that in low-score group and high-score group (P=0.023, P=0.002). There was a significant difference in Apo-A between the groups (P=0.009, P<0.001, P=0.013). The levels of TC, Apo-B and LPα in high-score group were lower than those in low-score group (P=0.008, P=0.001, P=0.002). The levels of HDL-C and Apo-B/Apo-A ratio in both middle-score and high-score group were lower than those in low-score group (P=0.008, P=0.001). The Spearman correlation analysis between various risk factors and Gensini score found that HDL-C and Apo-A had negative correlation with Gensini score (r=-0.166, r=-0.294), the ratios of LDL-C/HDL-C and Apo-B/Apo-A were positively correlated with Gensini score (r=0.159, r=0.170). By multi-factor linear regression, Apo-A was negatively related with Gensini score (β=-62.249), and Apo-B/Apo-A ratio was positively associated with Gensini score (β =31.311). Conclusion: Apo-A and Apo-B/Apo-A ratios are the independent risk factors for the stenosis degree of coronary artery in patients with CHD. They are reliable predictors for the risk of CHD.
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Objective To evaluate the AASI in the prognosis of patients with coronary heart disease by investigating the correlation between ambulatory arterial stiffness index and degree of coronary artery stenosis and risk score.Methods A total of 187 patients admitted to our hospital with diagnosis of coronary heart disease from Januaty 2015 to June 2016 were grouped by AASI.We compared the data in different groups about common character,coronary lesion count and investigate the correlation between ambulatory arterial stiffness index and Gensini scores and GRACE score.Results The general clinical data:there were no significant differences in male patients,the proportion of smoking,blood lipids,urea nitrogen (BUN),creatinine (Cr),body mass index (BMI) between the two groups.Significant differences were observed in older patients and those with hypertension and diabetes.The number of disease dvessels,three vascular lesions in the increased AASI group was more than normal AASI group.AASI was correlated with total Gensini scores positively.AASI was correlated with GRACE score positively.Conclusion AASI not only helps estimate the degree of coronary artery stenosis lesions,but also can be used to predict the prognosis of coronary heart disease.
ABSTRACT
Objective To evaluate the AASI in the prognosis of patients with coronary heart disease by investigating the correlation between ambulatory arterial stiffness index and degree of coronary artery stenosis and risk score.Methods A total of 187 patients admitted to our hospital with diagnosis of coronary heart disease from Januaty 2015 to June 2016 were grouped by AASI.We compared the data in different groups about common character,coronary lesion count and investigate the correlation between ambulatory arterial stiffness index and Gensini scores and GRACE score.Results The general clinical data:there were no significant differences in male patients,the proportion of smoking,blood lipids,urea nitrogen (BUN),creatinine (Cr),body mass index (BMI) between the two groups.Significant differences were observed in older patients and those with hypertension and diabetes.The number of disease dvessels,three vascular lesions in the increased AASI group was more than normal AASI group.AASI was correlated with total Gensini scores positively.AASI was correlated with GRACE score positively.Conclusion AASI not only helps estimate the degree of coronary artery stenosis lesions,but also can be used to predict the prognosis of coronary heart disease.