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1.
Interdisciplinaria ; 28(1): 37-56, jul. 2011. ilus, tab
Article in Spanish | LILACS | ID: lil-633480

ABSTRACT

Se llevó a cabo la adaptación de la Batería para la Evaluación de la Memoria Semántica en Demencia de tipo Alzheimer (Peraita, González Labra, Sánchez Bernardos & Galeote Moreno, 2000)¹ para su aplicación en la Ciudad de Buenos Aires (República Argentina). Esta batería permite evaluar mediante pruebas de modalidad visual, verbal y auditiva, el deterioro del conocimiento de seis categorías semánticas de seres vivientes y no vivientes. Ha sido desarrollada para población de habla hispana con la finalidad de evaluar el deterioro semántico en la Demencia de tipo Alzheimer. Su valor radica en que complementa la evaluación neuropsicológica, donde los aspectos de la memoria semántica por lo general están poco representados, otorgándole valor predictivo al posibilitar la detección temprana de determinadas patologías en las que se encuentra afectado ese sistema de la memoria. Se administró la batería a 30 sujetos sin deterioro cognitivo que tenían entre 61 y 88 años de edad y un promedio de 12 años de escolaridad. Los participantes fueron cuidadosamente seleccionados y se excluyeron a quienes pudieran presentar indicadores de deterioro cognitivo. La evaluación de los ítemes se realizó en base a la frecuencia de las respuestas correctas. Se tomó este criterio considerando que se trata de variables categóricas y el tamaño de la muestra. Se estimó la proporción de respuestas correctas en las seis categorías y dominios de seres vivientes y seres no vivientes. Los nuevos ítemes fueron seleccionados respetando la estructura de la batería y considerando su correlación entre las distintas pruebas.


In this work some items of the Evaluation Battery for Semantic Memory Deterioration in Alzheimer's Disease, were adapted to be used in the population of Buenos Aires city - República Argentina (EMSDA -in Spanish-, Peraita, González Labra, Sánchez Bernardos, & Galeote Moreno, 2000). The original battery presents a series of tasks, elaborated with the aim of assessing semantic deterioration and/or conceptual memory in patients with Alzheimer's disease. It allows specifically, assessing some features of the semantic visual and verbal knowledge of six categories concerning to living / animated beings and inanimate objects as well as the attributes that organize them. The evaluation of attributes belonging to the categories assessed by the EMSDA is implemented following a conceptual representation model, according to which attributes can be grouped in at least nine common conceptual components for the living things and inanimate objects categories. This conceptual representation model was constructed on the basis of an empirical approximation to the study of formation and representation of natural categories and objects representation (Peraita, Elosúa, & Linares, 1992). The various conceptual components vary in their frequency, according to the level of generality of the categories (superordinate, basic, or subordinate), category type, age, and education level, verifying this tendency in samples of patients with dementia of the Alzheimer´s type (DAT). The purpose of this paper is to present the items adjustment of some tasks of the EMSDA to the population of Buenos Aires city. The battery was administered to 30 healthy elderly between 61 and 88 years and 12 years average of education. The participants were carefully selected to be included in the sample. To rule out cognitive deterioration we did not include participants whose performance in the Mini Mental State Examination and the Wechsler Memory Scale Revised were one standard deviation bellow the expected scoring for age and educational level. To study the items we evaluated the frequency of answers, considering them more suitable when 75% or more participants gave the expected target. This criterion was chosen considering the variables were categorical, and the sample was formed with healthy elderly participants, i.e. without cognitive deterioration. To this preliminary analysis, it was estimated the proportion of correct answers to the six categories belonging to domains of living beings and in animate objects with the original and new items. We observed that some of them did not reach the 75% of agreement, and consistently, we determined to change the following tasks: Picture Naming, Spoken Word / Picture Matching, Sentence Verification, and Semantic Analogies. We selected new items taking into account the structure of the original version of the battery, and their correlations between the tasks. This new items were administered to 28 participants of the original sample. The means of each task were analyzed by Students distribution obtaining higher scorings with the adapted items (p < .0001). It is important to note that the proportion of expected answers to the living / animate and non living / inanimate objects were similar. The same results were observed to the supra ordinate and basic level of the category. However, to study the reliability of these results it would be necessary to explore the items in a larger sample. These preliminary results indicate that the new items can be considered an appropriate adjustment to our social culture context and to determine semantics impairments. This is considered a useful tool for the neuropsychological assessment to investigate the category specific deficits and other cognitive processes.

2.
Rev. chil. neuropsicol. (En línea) ; 5(3): 214-226, dic. 2010. tab
Article in Spanish | LILACS | ID: lil-579537

ABSTRACT

Introducción: El Grupo de Neurociencias de Antioquia utiliza como protocolo de evaluación cognitiva la batería cognitiva del CERAD. Objetivo: Validar una serie de pruebas neuropsicológicas utilizadas para el diagnóstico de enfermedades neurodegenerativas en una población colombiana. Procedimiento: La muestra estuvo conformada por 848 participantes. Además 151 personas con demencia de Tipo Alzheimer (DTA) y 36 con Deterioro Cognitivo Leve (DCL). Resultados: Para los dominios cognoscitivos evaluados se encontraron coeficientes de consistencia superiores a 0.70. La confiabilidad test-retest presentó coeficientes de correlación intraclase mayores a 0.70. Entre grupos se encontraron diferencias estadísticamente significativas (p<0.05). Se encontraron correlaciones de moderadas a altas entre las pruebas neuropsicológicas y las escalas que miden severidad de la demencia y la funcionalidad. Discusión: Las pruebas utilizadas son útiles para la evaluación de las enfermedades neurodegenerativas, la comunidad científica podrá contar con normas ajustadas a los factores sociodemográficos característicos de nuestra población y otras que presenten características similares a esta población colombiana.


Introduction: Antioquia Neurosciences Group used as a cognitive assessment protocol, the CERAD cognitive battery. Objective: To validate a series of neuropsychological tests used for diagnosis of neurodegenerative disease in a Colombian population. Procedure: The sample consisted of 848 participants. In addition 151 people with dementia of Alzheimer type (DAT) and 36 with mild cognitive impairment (MCI). Results: For the cognitive domains assessed by this protocol consistency coefficients were above 0.70. The test-retest reliability intraclass correlation coefficients showed greater than 0.70. Between groups differences were statistically significant (p <0.05). We found moderate to high correlations between neuropsychological tests and scales that measure severity of dementia and functionality. Discussion: The tests used are useful for the evaluation of neurodegenerative diseases, the scientific community may have rules tailored to the sociodemographic characteristics of our population and that may be useful in populations that have similar characteristics to this Colombian population.


Subject(s)
Humans , Male , Female , Middle Aged , Alzheimer Disease/diagnosis , Neurodegenerative Diseases/diagnosis , Neuropsychological Tests/standards , Cognition Disorders/diagnosis , Age and Sex Distribution , Colombia , Cross-Sectional Studies , Educational Status , Reproducibility of Results
3.
Rev. chil. neuropsicol. (En línea) ; 5(2): 153-159, jul. 2010. tab, graf
Article in Spanish | LILACS | ID: lil-579531

ABSTRACT

Introducción: el deterioro cognitivo leve (DCL) se caracteriza por la alteración de uno o varios procesos cognitivos sin afectación significativa en las actividades de la vida diaria del paciente y que puede presentarse acompañado de síntomas neuropsiquiátricos, lo que incrementa el riesgo a evolucionar a demencia. Objetivo: identificar la frecuencia y severidad de las alteraciones comportamentales en una población con deterioro cognitivo leve de tipo amnésico. (DCL-A)Procedimiento: estudio no experimental, transversal de alcance descriptivo, que contó con 70 personas, con diagnostico de DCL-A. Seleccionada la muestra los cuidadores respondieron el inventario neuropsiquiátrico. Resultados: el 65.7 por ciento de los participantes presentaron síntomas comportamentales, donde la irritabilidad fue la mas frecuente (32.9 por ciento), seguido por depresión (30 por ciento) y agitación (25.7 por ciento). La apatía fue el síntoma que se presenta con mayor severidad sin ser el más frecuente. Discusión: dentro del cuadro clínico propio del DCL-A se reportan síntomas neuropsiquiátricos que acompañan el déficit cognitivo. En la población estudiada el 65.7 por ciento presentaba dichos síntomas, dato que se aproxima a lo encontrado en la literatura; sin embargo el síntoma más frecuente fue la irritabilidad, no la depresión como se ha reportado en otros estudios; los síntomas menos frecuentes fueron conductas eufóricas y conductas motoras aberrantes.


Introduction: Mild Cognitive Impairment (MCI) is characterized by the alteration of one or more cognitive processes without significant impairment in the activities of patient’s daily life and may be accompanied by neuropsychiatric symptoms, which increase the risk to develop dementia. Objective: To identify the frequency and severity of behavioral alterations in a population with mild cognitive impairment amnesiac type (MCI-A) Procedure: non experimental study, with a cross-sectional descriptive scope, attended by 70 people with diagnosis of MCI-A.Selected sample of caregivers responded neuropsychiatric inventory. Results: 65.7 percent of participants had behavioral symptoms, where irritability was the most frequent (32.9 percent), followed by depression (30 percent) and agitation (25.7 percent). Apathy was the symptom presented with most severity but not the most frequent. Discussion: Neuropsychiatric symptoms that accompany cognitive deficits are reported in clinical features of MCI-A. In the population studied, 65.7 percent had such symptoms, data that approximates those found in literature. Nonetheless, the most common symptom was irritability and not depression, as has been reported in other studies; euphoric and aberrant motor behaviors were theless frequent symptoms.


Subject(s)
Humans , Male , Female , Middle Aged , Aged, 80 and over , Aging , Amnesia/epidemiology , Neuropsychological Tests , Cognition Disorders/epidemiology , Alzheimer Disease , Amnesia/pathology , Caregivers , Cross-Sectional Studies , Colombia/epidemiology , Surveys and Questionnaires , Severity of Illness Index , Mental Disorders/epidemiology , Cognition Disorders/pathology
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