ABSTRACT
Objective@#To analyze the application of difficulty degree index (DDI) in predicting patients′s fertility outcome after laparoscopic myomectomy.@*Methods@#A retrospective study was carried out on 118 patients with subserous myoma or intramural myoma undergoing laparoscopic myomectomy from January 2005 to December 2014. The rate of post-operative pregnancy, delivery outcome and disease recurrence were investigated. Logistic regression analysis was used to analyze the impact of DDI, the age of patients undergoing surgery, presence of infertility history etc, on the patients′ reproductive outcome following the surgery.@*Results@#Follow-up for 1 to 10 years,118 cases were included in the study, the rate of post-operative pregnancy, live birth, vaginal delivery were 72.9% (86/118) , 52.5% (62/118) and 24.2% (15/62) respectively. No cases of uterine rupture and obstetric complications occurred. Univariate analysis showed that the independent variables of post-operative pregnancy rate were DDI, patient′s age at the time of surgery, presence of infertility history and myoma recurrence (all P<0.05) . In multivariate analysis, the factors of post-operative pregnancy rate were DDI (OR=3.131, 95%CI:1.012-8.894) , patient′s age at the time of surgery (OR=2.722, 95%CI:1.048-7.067) and presence of infertility history (OR=8.509, 95%CI: 2.102-34.445) .@*Conclusions@#DDI could be applied to predict post-operative pregnancy rate, with the increasing of DDI the post-operative pregnancy rate decreasing. The patients with high DDI scores, age>35 years old or presence of infertility history should get ready for pregnancy positively.
ABSTRACT
Objectives to evaluate the quality of examination paper of natural product chemistry of clinical pharmacy for Grade 2005 so as to feed back teaching information and provide gist for improving the teaching quality.Methods Selecting examination paper of all the students of clinical pharmacy to analyze.Results The examination achievement accords with normal distribution with average(78.64?11.12),difficulty 0.62 and discrimination 0.40.Conclusion The model of the paper has the full-scale distribution,the discrimination is good,and it evaluates the mastery level of the students quite objectively.The training of students analysis ability and comprehensive judging ability should be strengthened in the future.