ABSTRACT
Introducción. Las enfermedades digestivas (ED) no neoplásicas son causas importantes de consulta médica y hospitalización. Objetivo. Determinar la mortalidad por ED no neoplásicas en la población adulta del Perú entre 2010 y 2015. Métodos. Análisis secundario del registro de defunciones por ED no neoplásicas en la población mayor de 18 años entre los años 2010 y 2015 de la Oficina General de Estadística e Informática del Ministerio de Salud del Perú. La población para el mismo periodo se obtuvo del Instituto Nacional de Estadística e Informática. Se calcularon las tasas de mortalidad estandarizada (TME x 100 000 personas-año). Resultados. Durante el período 2010-2015 se registraron 39 889 muertes por ED no neoplásicas. Las TME más altas fueron para el grupo de las enfermedades del hígado (12,2 x 100 000 personas-años), siendo la fibrosis y cirrosis del hígado la de mayor mortalidad (9,1). La pancreatitis aguda (1,0) tuvo mayor TME que la úlcera gástrica (0,7). Las TME, según las regiones del Perú, fueron altas por fibrosis y cirrosis del hígado en Piura (16,3), Lambayeque (14,6) y La Libertad (14,4); por colelitiasis (1,1) y colecistitis aguda (1,7), en Puno; por pancreatitis aguda (2,2), en Tacna; y por úlcera gástrica fue mayor en Huancavelica (3,6) y Huánuco (2,3). Conclusiones. La fibrosis y cirrosis del hígado fue la ED no neoplásica con mayor tasa de mortalidad en la población adulta del Perú, principalmente en la costa norte del país.
Introduction. Non-neoplastic digestive diseases (DD) are important causes of medical consultation and hospitalization. Objective. To determine the mortality by non-neoplastic DD in the adult population of Peru between 2010 and 2015. Methods. Secondary analysis of the registry of non-neoplastic DD deaths in the population over 18 years old between 2010 and 2015 of the General Office of Statistics and Informatics of the Ministry of Health of Peru. The population for the same period was obtained from the National Institute of Statistics and Informatics. The standardized mortality rates (SMR x 100 000 person-years) were calculated. Results. During the period 2010-2015 there were 39 889 deaths due to non-neoplastic DD. The highest SMR were for the group of liver diseases (12,2 x 100 000 person-years), with fibrosis and cirrhosis of the liver having the highest mortality (9,1). Acute pancreatitis (1,0) had higher SMR than gastric ulcer (0,7). The SMR, according to the regions of Peru, were high due to fibrosis and cirrhosis of the liver in Piura (16,3), Lambayeque (14,6) and La Libertad (14,4); by cholelithiasis (1,1) and acute cholecystitis (1,7), in Puno; for acute pancreatitis (2,2), in Tacna; and gastric ulcer was higher in Huancavelica (3,6) and Huánuco (2,3). Conclusions. Liver fibrosis and cirrhosis was non-neoplastic DD with a higher mortality rate in the adult population of Peru, mainly in the northern coast of the country.
ABSTRACT
Food allergy refers to the body's abnormal immune response to food,which induces disorder and/or injuries of human body,and thus triggers a series of manifestations.Ninety percent of food allergy is due to the following allergen:milk,eggs,peanuts,nuts,seafood,soy,wheat,etc.The symptoms of digestive system are closely associated with the nature of allergen (including protein's family nature,three dimensional structure,biological activity and stability) and the body's own status (genetic factors,integrity of intestinal mucosal barrier and oral immune tolerance).The symptoms of digestive systems are not typical,and differ by various factors like body conditions,ages,regions and allergens,so the diagnosis is difficult.Food allergy is categorized by its mechanism:IgE,non IgE,and mix.The symptoms of digestive systems include vomiting,diarrhea,reflux,constipation and abdominal pain,etc,and relative diseases include food protein-induced enteropathy,food protein-induced enterocolitis syndrome,food protein-induced enterocolitis syndrome,food protein-induced proctocolitis,celiac disease,eosinophilic gastroenteritis,eosinophilic esophagitis and infantile colic,etc.Delayed diagnosis will result in failure to thrive,anemia and hypoproteinenia.Therefore,early diagnosis and treatment can effectively prevent malnutrition and improve the children's animation.