A Case of Acquired Progressive Lymphangioma / 대한피부과학회지

Acquired progressive lymphangioma is a rare, benign cutaneous tumor of lymphatic endothelial cells. We report a case of acquired progressive lymphangioma in a 24-year-old man who presented a 1 X 1cm sized erythematous papule on his chin over a long period. Histopathologic examination revealed irregularly dilated vascular channels in the papillary dermis and anastomosing cleft-like vascular spaces in the lower dermis with a dissection of collagen. The cells lining the channels showed focal hobnail appearance but no atypia or mitotic figures. Immunohistochemically, they were not stained with factor VIII-related antigen, CD34, and CD31.

A Case of Progressive Acquired Lymphangioma / 대한피부과학회지

Acquired progressive lymphangioma is a benign lymphatic proliferation characterized clinically by gradually enlarging erythematous patches and histopathologically by dermal vascular channels with "dissection of collagen" appearance. A 30-year-old woman presented a 6x4cm sized, erythematous patch on the right thigh, which had been gradually enlarging for 10 years since she had had a burn injury on the same site. Histopathologic findints of the lesion showed vascutar channels forming a network in the dermis with a "dissection of collagen" appearance. The cells lining the channels were stained with antibodies against muscle actin, factor VIII-related antigen, Ulex europaeus agglutinin I, CD34, and CD31. We made a diagnosis of acquired progressive lymphangioma and have been observing the course of the disease without specific treatment.