Research Progress on Pathogenic Factors of Breast Cancer Combined with Thyroid Cancer / 肿瘤防治研究

Thyroid cancer and breast cancer are two of the most common malignant tumors in women. Concurrent tumors of the thyroid and breast are relatively rare in clinical practice; however, the incidence of such dual malignancies has recently increased. Researches conducted in the past mainly focused on the possible increase in the incidence of contralateral breast cancer, while the increased risk of synchronized thyroid cancer in women with breast cancer has attracted widespread attention recently. The specific mechanism has not been fully understood. This article reviews the pathogenic factors between these two diseases, and evaluates the etiological role of these factors in these double primary cancers, so as to provide a better basis for clinical practice.

A Case of Synchronous Squamous Cell Carcinoma of the Bladder and Transitional Cell Carcinoma of the Ureter / 대한비뇨기과학회지

The occurrence of double primary tumors in an individual patient was first described by Billroth approximately 100 years ago. The genitourinary organs appear to be at greater risk for double primary tumors, because the urological system is at higher risk for primary tumors( prostate and bladder ). Multifocal involvement is a well-known feature of transitional cell carcinoma. But the coexistence of two separate primary urothelial carcinomas occurring simultaneously is extremely unusual. We report on a 25-year-old man who had synchronous double primary tumors : squamous cell carcinoma of the bladder and transitional cell carcinoma of the ureter.