ABSTRACT
Introduction: According to WHO definition, "Rational use ofdrugs requires that patients receive medications appropriate totheir clinical needs, in doses that meet their own individualrequirements for an adequate period of time, at the lowest costto them and their community".Methodology: 200 randomly prescription were included in thisstudy. This study was conducted in Department of Surgery inthe Government Medical College, Badaun. The duration ofstudy was over a period of six month.Result: 200 randomly prescription were included in thisstudy.115 fixed combination of different drug were prescribed.These 115 drugs were prescribed for a total of 1159 times/drug encounters. In our study, the route of administration ofdrug 44.1% by oral, 47.4% injectable and rest were by otherlike inhalation, subcutaneous & tropical routes.Conclusion: This study concludes that polypharmacy,overuse of injectable and prescribing by brand names were thechallenges identified