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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 138-140, 2017.
Article in Chinese | WPRIM | ID: wpr-509634

ABSTRACT

Objective To investigate the clinical therapeutic effect of Xianyimucao capsule on hormone level and menstrual recovery in patients with vaginal bleeding after drug abortion.Methods 102 pregnant women with drug abortion admitted in our hospital from June 2015 to December 2016 were selected and divided into two groups by random number table, the control group was given conventional hemostasis and such symptomatic treatment as anti-infection, the observation group was given Xianyimucao capsule on the basis of control group.The clinical efficacy, the levels of serum hormones and menstrual recovery before and after the treatment of the two groups were compared.Then the safety of two groups were evaluated.Results After 14 days of the treatment, the total effective rate of the observation group was 96.1%, which was significantly higher than 80.4% of the control group (P<0.05).And the serum HCG, P and E2 levels in the two groups after the treatment were significantly lower than those before the treatment (P<0.05);serum hormone levels of the observation group were significantly better than that the control group (P<0.05).Compared with the control group, the menstruation recovery of the observation group was significantly shortened (P<0.05);there was no significant difference of the first menstrual cycle and menstrual volume after the menstruation recovery between the two groups.There was no obvious adverse reaction in the two groups during meditation. Conclusion The application of fresh motherwort capsules in the treatment of vaginal bleeding after drug abortion can stop bleeding rapidly , regulate the body's hormone levels and recover normal menstruation with high safety .

2.
Chinese Journal of Biochemical Pharmaceutics ; (6): 397-398,402, 2017.
Article in Chinese | WPRIM | ID: wpr-613849

ABSTRACT

Objective To study the effect of transvaginal ultrasound on the size of gestational sac and drug abortion, and to explore the relationship between the effect of drug abortion and the gestational sac size.MethodsIn our hospital in July 2016 were treated 50 cases of drug abortion of pregnant women as the research object in the process in February 2015, a retrospective analysis of 50 cases of pregnant women, patients were divided into gestational sac and greater than 10 and less than 10mm to 25mm 25mm three.Transvaginal ultrasound was performed before taking the medicine.After 7 days, the patients were examined by transvaginal ultrasound.The results showed that 7 patients had abortion failure, and the other 5 patients had incomplete abortion.ResultsTransvaginal ultrasound monitoring results can be obtained, the gestational sac size of less than 10 mm in patients with a total of 13 cases, abortion in patients with failure of the 2 cases, incomplete abortion in 4 cases, complete abortion in 7 cases, abortion failure probability was 15.4%.The gestational sac size ranged from 10mm to 25mm in a patient with a total of 25 cases, with a miscarriage of failure in a total of 2 patients, incomplete abortion in a total of 2 patients, complete abortion in a total of 21 patients, and a miscarriage probability of failure of up to & 8%.The gestational sac size is greater than 25 mm in patients with a total of 12 cases, the abortion of the failure of the patients in the 4 cases, incomplete abortion in the 2 cases, complete abortion in the 6 cases, the probability of abortion failure was 33.3%.Therefore, there was a significant difference between the three groups in the rate of abortion failure (P<0.05).ConclusionThe process of drug abortion in pregnant women, the use of transvaginal ultrasound monitoring, can monitor the situation of pregnant women with gestational sac in a certain extent, and that the effect of drug abortion, is conducive to the treatment and the subsequent operation, thereby reducing the pain of patients, improve the success rate of miscarriage.

3.
Chinese Journal of Biochemical Pharmaceutics ; (6): 119-121, 2017.
Article in Chinese | WPRIM | ID: wpr-612910

ABSTRACT

Objective To explore the effect of abortion, effect of Yunnan Baiyao Combined with Wujia Shenghua capsule in patients with medical abortion vaginal bleeding time.MethodsSelect 98 cases from March 2014 to May 2016 by drug abortion in second hospital of shandong university, were randomly divided into combined group and control group with 49 cases in each group, two groups were given routine drug treatment, combined group was given Yunnan Baiyao combined with Wujia Shenghua capsule, comparing the two groups of patients with abortion, vaginal bleeding time.ResultsCombined group and control group differences in the complete abortion rate was not statistically significant, combinde group of pregnant sac discharge time is shorter than the control group (P14 days the percentage of patients were lower than those in control group (P menstruation (24.49%) and the control group (12.24%, 38.78%, 46.94%) with significant difference (P<0.05);combined group of menses time, menstrual duration compared with the control group, the difference was not statistically meaning.ConclusionYunnan Baiyao combined with Wujia Shenghua capsule can accelerate the gestational sac discharge, shorten the time of vaginal bleeding, reduce the amount of vaginal bleeding.

4.
Rev. cuba. obstet. ginecol ; 36(1): 97-108, ene.-mar. 2010.
Article in Spanish | LILACS | ID: lil-584611

ABSTRACT

OBJETIVO: evaluar la eficacia y seguridad del misoprostol vaginal como abortivo y la indicación de este proceder en la adolescencia. MÉTODOS: nuestra investigación se trata de un ensayo clínico aleatorio, abierto, monocéntrico, con un grupo de tratamiento para extender el uso de un método abortivo farmacológico en pacientes que solicitan interrupción de la gestación hasta las 12 sem de embarazo y hasta los 20 años de edad. Se incluyeron todas las pacientes adolescentes que acudieron a la consulta de interrupción de embarazo del hospital Ramón González Coro y que cumplieron con los criterios de inclusión, en un cohorte de 100 casos. RESULTADOS: los resultados encontrados muestran que el 89 % de las adolescentes tenían más de 16 años, las primeras relaciones sexuales (76 %) fueron antes de los 16 años y las infecciones de tramisión sexual (ITS) aparecen en el 51 %. Con respecto al método el 71 % expulsó antes de las 16 h de impuesto (primera y segunda dosis) con una tasa de fallo del 8 %.Todas fueron estudiadas con US a las 72 h. El 85 % considera satisfactorio el método y 96 salieron con algún método anticonceptivo. CONCLUSIÓN: el uso del misoprostol por vía vaginal en la adolescencia resultó ser un método útil y confiable como alternativa para la interrupción del embarazo en el primer trimestre


OBJECTIVE: To assess the effectiveness and safety of vaginal Misoprostol as abortive method and indication of this procedure during adolescence. METHODS: Present research is a monocenter, open, randomized clinical trial with a group of treatment to extend the use of a pharmacologic abortive method in patients requesting pregnancy termination until the12 weeks and also until 20 years old. All the adolescent patients seen in pregnancy termination consultation of ½Ram¾n Gonzßlez Coro» Gynecology and Obstetrics Hospital fulfilling with inclusion criteria in a group of 100 cases are included. RESULTS: Results achieved show that the 89 percent of adolescents aged over 16, their first sexual intercourses were before 16 years and ITS (appear in the 51 percent. Regarding the method, the 71 percent had a expulsion rate before the 16 h of application (first and second dose) with an 8 percent failure rate. All were studied using US at 72 h. The 85 percent considers that the method was satisfactory and in the 96 percent some contraceptive method was used. CONCLUSION: The use of vaginal Misoprostol during the adolescence was a useful and reliable method as alternative for pregnancy termination at first trimester


Subject(s)
Humans , Female , Pregnancy , Adolescent , Abortion, Induced/methods , Misoprostol/therapeutic use
5.
International Journal of Traditional Chinese Medicine ; (6): 439-440, 2009.
Article in Chinese | WPRIM | ID: wpr-392733

ABSTRACT

ObJective To investigate the therapeutic effect of the Traditional Chinese Medicines on bleeding after drug-abortion. Methods 193 patients who volunteered to receive drug-abortion were randomly recruited into a treatment group (97 cases) and a control group (96 cases). The treatment group and control group were taken with traditional Chinese medicines and Yimueao ointment respectively after both groups were administrated with Mifepristone and Misoprostol orally for drug miscarriage. Results The rate of complete abortion, in-complete abortion and failure of treatment in treatment group was 93.81 %, 5.16% and 1.03% respectively, and those of control group were 85.42%, 11.45% and 3.13% respectively. The results showed significant difference between the two groups (P<0.05) . The difference of vaginal bleeding amount and its lasting time between the two groups was also statistically significant (P<0.01) . Conclusion The compound Chinese herbs with the functions of promoting blood circulation to dissipate blood stasis has obvious effects on the treatment of incomplete drag-abortion.

6.
Journal of Medical Research ; (12)2006.
Article in Chinese | WPRIM | ID: wpr-560951

ABSTRACT

Objective To study the affection of acanthopanacis biochemical capsule to drug abortion in clinics.Methods 600healthy pregnant women were divided into three groups randomly;200 group A,oral intake of acanthopanacis biochemical capsule after drug abortion,200 group B oral intake of Yimuwan after drug abortion,200 group C as control.Results The discharging rate of pregnant cyst within 3days were 84.62% in grpup A,63.64% in group B and58.33% ingroup C.Theoccurrence rate of incomplete abortion within 2weeke were 1.50%in group A,6.00% in group B and 91.67% in group C .The rate of vagina bleeding within 2 weeks were 9.50% in group A,97.50% in group B and 69.80% in group C.The rate of vagina bleeding over 1 month were 1.00% in group A,6.50% in group B and 7.50%in group C.The emergency operation due to great hemorrhage were 1 in A,7 in B and 9 in C.The uterus infection were 1 in A,13 in B and 15 in C.Conclusions Acanthopanacis biochemical capsule could increase the successful fate of dug abortion within 3 days and decrease the chance of inconplete abortion .It could shorten the tine of vagina bleeding and the happening of complication.

7.
Journal of Medical Research ; (12)2006.
Article in Chinese | WPRIM | ID: wpr-559784

ABSTRACT

Objective To describe the imaging of the vagina massive hemorrhage patients,which is caused by pero-abortion by the high-frequency ultrasonic examination,and to establish the character of ultrasound.Methods 56 patients,who have the vagina massive hemorrhage after the drug abortion,were checked by the high-frequency ultrasonic examination,to observe if there are fetus in the uterus.Results There all have fetus in the uterus in 56 patients by the high-frequency ultrasonic examination.Including 8 patients who have little residues;22 patients have residues complic fluidify in the uterus;26 patients have admix residues.Conclusions After the drug abortion,the vagina massive hemorrhage,which is caused by pero-abortion,is the severity complication endangering the life of the patients,we cound found the pero-abortion early by the high-frequency ultrasonic examination and clinical observe.

8.
China Journal of Traditional Chinese Medicine and Pharmacy ; (12)2006.
Article in Chinese | WPRIM | ID: wpr-566242

ABSTRACT

Objective:To observe the e ect of Gongqing grain on the expression of Caspase-3 and Caspase-8 in the human's villi and decidua in early pregnancy teminated by drug,discuss the mechanism of Gongqing grain protecting and treating hemorrhage after drug-induced abortion.Methods:180 patients were divided into three groups randomly:Gongqing grain group,Qianzhi capsule group and drug abortion group,and arti cial abortion group(n=60)was set.The immunohistochemical method was used to observe the expressions of Caspase-3、8 in the villi and deciduas.Results:The level of Caspase-3、8 in the villi and deciduas decreased more signi cantly in Gongqing grain group than the other three groups(P

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