1.
International Journal of Surgery
;
(12): 698-701, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-420478
ABSTRACT
Gemcitabine has become a first-line chemotherapeutic durg.Unfortunately,many patients fail to derive benefits from gemcitabine in clinics.The variability of human equilibrative nucleoside transporter 1 (hENT1)expression in tumor cells,which plays a dominant role in the transport of gemcitabine across the cell membrane,may be one of the reason for gemcitabine chemoresistance in pancreatic cancer.