ABSTRACT
Objective To study the effects of modified Duhuo-Jisheng decoction for treatment of paresthesia after transforaminal endoscopic discectomy in patients with lumbar disk herniation. Methods A total of 89 lumbar disk herniation patients with paresthesia after transforaminal endo-scopic discectomy were divided into the control group (n=44) and the treatment group (n=45) by random number table method. The control group were treated with mecobalamin capsule, and the treatment group treated modified Duhuo-Jisheng decoction. The two groups were treated for 4 weeks. The VAS scale was used to evaluate the pain level of the lower extremities, and the nylon rope test score was used to evaluate the numbness of the lower extremities; and the Oswestry Disability Index was used to evaluate lumbar function; and the World Health Organization Quality of Life (WHOQOL-BREF) was used to evaluate the quality of life. The clinical efficacy of the two groups was compared. Results The total effective rate was 93.3％ (42/45) in the treatment group and 75.0％ (33/44) in the control group. There were significant differences between the two groups (χ2=5.641, P<0.05). After treatment, the VAS score and ODI score in the treatment group were significantly lower than those in the control group (t=11.440, 8.976, P<0.01). The nylon rope test score and WHOQOL-BREF score were significantly higher than those of the control group (t=10.524, 6.221, P<0.01). Conclusions The modified Duhuo-Jisheng decoction can significantly improve pain and numbness of lower extremities, lumbar function and quality of life in lumbar disk herniationpatients with paresthesia after transforaminal endo-scopic discectomy.
ABSTRACT
Objective To evaluate the curative effect of the Duhuo-Jisheng decoction in treating knee osteoarthritis (KOA) with the deficiency of liver and kidney. Methods Using the random number table method, a total of 80 KOA patients were randomly divided into 2 group, 40 in each group. The treatment group were treated with Duhuo-Jisheng decoction, and the control group with glucosamine sulfate orally. The 2 groups were treated with 30 day. The blood sedimentation (ESR) of before and after treatment was detected. The level of C-reactive protein (CRP) was detected by latex enhanced immunization. The degree of knee joint pain was evaluated by VAS scale. The severity of the symptoms was evaluated by the visual scale of Osteoarthritis Index (Western Ontario Mac Master University Osteoarthritis index, WOMAC index). The changes of TCM symptoms were observed and the clinical effective rate was evaluated. Results The total effective rate of the treatment group was 95% (38/40), while the control group was 77.5% (31/40). The difference between the 2 groups was statistically significant (χ2=10.213, P=0.003). After treatment, the ESR (15.41 ± 4.23 mm/h vs. 17.6 ± 7.27 mm/h, t=-4.426), CRP (4.73 ± 1.28 mg/L vs. 6.12 ± 2.38 mg/L, t=-14.735) level in the treatemnt group were significantly lower than those in the control group (P<0.01). The VAS scores (2.5 ± 0.62 vs. 4.9 ± 0.8, t=-15.026), WOMAC index(12.1 ± 4.7 vs. 16.7 ± 6.7, t=-11.177) and TCM symptom score (6.5 ± 0.4 vs. 7.5 ± 0.4, t=-3.482) in the treatment group were significantly lower than those in the control group (P<0.01). Conclusions The Duhuo-Jisheng decoction is effective improve the symptom and quality of life of liver-kidney deficiency of KOA.