New Medical EMC Laboratory Solution / 中国医疗器械杂志

From the perspective of the organizers of medical electrical EMC laboratory, this paper elaborates the guiding principles, design ideas and experience of building medical EMC Laboratory. According to the needs of the laboratory, the basic requirements of anechoic chamber, the auxiliary room of anechoic chamber and other supporting rooms in the EMC laboratory are introduced. The key technologies of anechoic chamber, such as frequency range, shielding requirement and static zone, are mainly elaborated, so as to build a laboratory matching with test requirement.

Analysis of the Electromagnetic Compatibility Standard for Active Implantable Medical Devices Using in the Heart / 中国医疗器械杂志

In this paper,standards for active implantable cardiac medical devices are discussed.Potential EMC risks and its correspondent tests settings as well as the design principle of the tests have been analyzed.The problems arises from the difference between domestic and international standards on the limitation of exposure of the general public to electromagnetic fields and the lack of assessment of EMC risk which generated by the the 5th generation mobile communication for the impact on the active implantable devices devices.

Genetic diversity of Ehrlichia canis strains from naturally infected dogs in Rio de Janeiro, Brazil / Diversidade genética de cepas de Ehrlichia canis encontradas em cães naturalmente infectados no Rio de Janeiro, Brasil

The aim of this study was to characterize Ehrlichia canis strains from naturally infected dogs in Rio de Janeiro, Brazil. In addition, all the clinical and hematological findings observed in these dogs were reported. PCR targeting the 16S rRNA gene was used for diagnostic purposes, and the TRP19 and TRP36 genes were sequenced to evaluate the genetic diversity. Fifteen samples were positive for E. canis. The polymerase chain reaction for the TRP19 gene resulted in 11 amplicons (11/15), which were cloned into the pGEM-T easy vector for sequencing. The complete sequence of TRP19 gene was compared to those in the GenBank, revealing high identicalness. Phylogenetic analysis on the TRP36 gene sequences demonstrated two distinct strains from two dogs, named 56C and 70C. The 56C strain was grouped with the strain Cuiaba 16, which is a hybrid strain formed by Brazilian and US genogroups; and the 70C strain was grouped with other strains of the US genogroup, thus suggesting that there are at least two genogroups of E. canis in Rio de Janeiro (US and Brazilian). Those animals, in which the 70C and 56C strains were isolated, showed distinct clinical and hematological manifestations of 1the disease. The appearance of different genotypes may express new phenotypes, thus resulting in different forms of presentation of the disease and making its diagnosis more complex.

O objetivo deste estudo foi caracterizar as cepas de Ehrlichia canis em cães naturalmente infectados no Rio de Janeiro, Brasil. Além disso, os achados clínicos e hematológicos observados nos cães foram relatados. O gene 16S rRNA foi utilizado como alvo da PCR para fins diagnósticos, e os genes TRP19 e TRP36 para avaliar a diversidade genética. Quinze amostras foram positivas para E. canis. PCR para o gene TRP19 produziu 11 amplicons (11/15) que foram clonados no pGEM-T easy vector para sequenciamento. A comparação das sequências completas do gene TRP19 com outras sequências depositadas no GenBank revelou uma alta identidade. Duas amostras (56C e 70C) após o ensaio da PCR, tendo como alvo o gene TRP36, geraram sequências, e a análise filogenética mostrou que a cepa 56C foi agrupada com a cepa Cuiabá 16, que é uma cepa híbrida, formada pelo genogrupo Brasileiro e o genogrupo US; e a cepa 70C agrupou com as outras cepas do genogrupo US, sugerindo a existência de pelo menos dois genogrupos de E. canis no Rio de Janeiro (US e Brasileiro). Esses animais apresentaram manifestações clínicas e hematológicas distintas, e diferentes genótipos podem expressar novos fenótipos, resultando em diferentes formas de apresentação da doença e fazendo com que o diagnóstico seja mais complexo.

Lipoidoproteinosis: relato de un caso / Lipoidoproteinosis: case report

La lipoidoproteinosis, es una enfermedad hereditaria autosómica recesiva, de presentación infrecuente, con manifestaciones clínicas características desde etapas tempranas de la vida y hallazgos histopatológicosdados por un depósito de lípidos y proteínas anormales de tipo hialino en diferentes tejidos.Presentamos el caso de una mujer de 18 años, valorada en nuestra consulta por la aparición de llanto y habla disfónica, asociados a lesiones cutáneas y mucosas, con diagnóstico clínico e histopatológico de lipoidoproteinosis, con buena respuesta terapéutica al dimetil-sulfóxido.Resaltamos que se trata de un caso de infrecuente presentación, cuyo enfoque temprano y multidisciplinario son esenciales para su pronóstico...

Lipoidoproteinosis is a rare autosomal recessive hereditary disease, with typical clinical features since first years of life and histopathological findings of deposits of lipids and abnormal hyaline-like proteins in different tissues. We report the case of an 18 year-old woman, examined at our clinic for the presence of dysphonic weeping and speech, associated with cutaneous and mucosal lesions with clinical and histopathological diagnosis of lipoidoproteinosis, that presented a good therapeutic response to dimethyl sulfoxide. We emphasize that this is a case of rare presentation, whose early and multidisciplinary approach is essential for prognosis...

Epithelial-Myoepithelial Carcinoma of the Parotid Gland: A Case Report

PURPOSE: Epithelial-myoepithelial carcinoma (EMC) represents about the 1% of the malignant neoplasms in the salivary glands and clinically most commonly found localized, well defined and sometimes presents orofacial pain. Treatment of choice is surgical excision. Postoperative radiotherapy can be used when surgical margins are doubtful. We report our experience of EMC of the parotid gland. METHODS: A 78-year-old man presented with a three-year history of a localized, painless, 7 x 6 cm sized recurred tumor in his right preauricular area. He was diagnosed as EMC of the right parotid gland. So a total parotidectomy was performed. In his old medical history, he had a mass in the same area 5 years ago. The diagnosis of pleomorphic adenoma was made and the mass excision was performed at the local clinic without further evaluation. RESULTS: It was unable to visually discriminate between the tumor and the normal tissue. So a total parotidectomy was performed. The patient was got post-operative radiotherapy and was followed up for 9 months. There was no specific evidence of recurrence. CONCLUSION: We present a case of EMC of the parotid gland in right preauricular area, which is uncommon. So we report a uncommon case of EMC to discuss about our experience with relevant journal discussion.

The Validity and Reliability of the EMC Device; For the Checking ofthe Mobility of the First Ray of the Foot / 대한정형외과학회잡지

PURPOSE: To evaluate the validity and intra-rater, inter-rater reliability of the EMC device used to check the mobility of the first ray of the foot. MATERIALS AND METHODS: Sixty-nine cases (43 patients) of mild to severe hallux valgus feet were enrolled in this study. For an analysis of the validity of the EMC device, the dorsal mobility of the first ray of the foot was measured using the modified Coleman block test and EMC device. The intra- and inter-rater reliability of EMC device was evaluated by measuring the dorsal mobility of the first ray of the foot twice with three independent raters blinded to other's results. The results were analyzed for the intra-rater reliability and for inter-rater reliability. RESULTS: The mean value of the dorsal mobility of the first ray of the foot by the EMC device and modified Coleman block test was 8.3 mm (range; 4.3-12.3 mm) and 7.4 mm (range; 3.4-10.3 mm), respectively. There was a significant difference between the EMC device and modified Coleman block test (p<0.05). However, both the measured data, showed a good correlation (Pearson correlation coefficient=0.84). The paired t-test for intra-rater reliability and ANOVA testing for inter-rater reliability showed no statistically significant difference. CONCLUSION: The EMC device is reliable and valid for measuring the mobility of the first ray of the foot.

A Case of Epithelial-myoepithelial Carcinoma of the Parotid Gland

Epithelial-myoepithelial carcinoma (EMC) of the salivary gland is a rare tumor that comprises approximately 1% of all salivary gland tumors. It has a distinctive histological appearance comprising ductal structures with an inner epithelial cell component and an outer layer of myoepithelial cells. We report a case of EMC of the parotid gland in a 41- year-old man. He presented left-sided subauricular swelling developed 3-month earlier. Neck CT scans revealed a well-defined mass in the left superficial parotid gland. He underwent superficial parotidectomy and was diagnosed as EMC. He was taken postoperative radiotherapy. There was no evidence of recurrence during a follow-up period of 12 months.

Electromagnetic Compatibility of Medical Devices on Health-Care Train / 医疗卫生装备

The problems of Electromagnetic Compatibility(EMC) and Electromagnetic Interference(EMI) of medical electric devices are directly related to the medical treatment effect for wounded patients on the health-care train.EMC and EMI problems of medical electric devices in use are studied and analyzed.Suggestions on preventing EMI problems are given to guarantee the normal running of medical electric devices in health-care train.

Epithelial-Myoepithelial Carcinoma of the Salivary Glands: Clinical Aspects and Treatment Outcome / 대한이비인후과학회지

BACKGROUND: The epithelial-myoepithelial carcinoma(EMC) of major and minor salivary glands is a low grade malignancy which shows frequent local recurrence. OBJECTIVES: The aim of this study was to define the clinical feature and treatment outcome of EMC of major and minor salivary glands. MATERIALS AND METHODS: Nine cases of EMC of major and minor salivary glands were reviewed retrospectively. RESULTS: The clinical course varied from slowly growing painless mass to the mass associated with facial nerve paralysis, bleeding or bone desutruction. Local recurrence was observed in 3 cases(33%) at 3, 10 and 11 months after primary resection, but no metastasis to periglandular, cervical lymph nodes or distant site occurred in our series including three recurrences. One of three recurrent patients died due to local extension of the tumor. Other two patients with recurrent tumors were successfully treated with revision operation and survived more than 2, 6 years without disease, respectively so far. Preoperatively these tumors were usually regarded as benign salivary gland tumor in CT scan except for the cases showing bone destruction. Atypical cells on fine needle aspiration cytology/frozen biopsy coupled with benign looking CT finding suggested low grade malignancy in which case EMC should be considered a differential diagnosis. Pathologic diagnosis was frequently confused with other high grade carcinoma rather than low grade carcinoma or benign tumor. This resulted in unnecessary postoperative radiotherapy, but clinically aggressive recurrent cases recurred despite radiotherapy. No malignant cells were found in clinically enlarged lymph nodes, and we have to retain positve attitude toward surgical management of advanced or recurrent EMC keeping in mind that recurrent tumor may inherit different tumor bilogy. CONCLUSION: Although epithelial-myoepithelial carcinoma is a rare salivary gland tumor, otolaryngologists should be aware of its existence because this low grade malignancy can cause diagnostic confusion during workup and also frequently be misdiagnosed as other high grade salivary malignancy in clinically aggressive form.

Mitigating EMI with healthcare electronic facilities referring to FDA recommendations / 医疗卫生装备

In view of China's medical equipment industry has not been equipped with a sound system and strict administration, it is wise to draw on FDA recommendations and seek effective ways of solving EMI problems. Further should focus on improving the performance of medical equipment so as to adapt to the different environment. In the end, the design of healthcare facilities to meet EMC standards is put forward specifically in four parts of electronic circuits, power circuits, display device, and the mechanical shell.

Development of LEEP electro-scalpel system / 医疗卫生装备

LEEP electro-scalpel is a type of cervical disease device. It belongs to the high frequency electro-knife in medical apparatus category. There is no domestic LEEP electro-scalpel at present. It is significant and important for the study group to resolve the safety and EMC problem and develop domestic LEEP electro-scalpel which is safe, stable and competitive in price while has the same surgery effect as the imported one.

Effects of total glucosides of paeony on sleep-waking rhythm in rats / 中国药理学通报

Total glucosides of paeony (TGP, 50 mg/kg 7d, ig) could enhance the episode duration of slow-wave sleep (SWS) in normal rats, and restore the sleep parameters in the insomniac rats induced by caffeine ( 1 2. 5 mg/kg 7 d,ip)nearly to the normal level. It (50 mg/kg 3 d,ig) also increased significantly thetotal time of SWS and paradoxical sleep (PS) in the swimming rats (water temperature 25?1℃, swimming time 30 min). These results suggest that TGP probably improve the sleep of rats under the different states.