Relations between hypertensive disorders in pregnancy and subsequent risk of early-term birth:a birth cohort study / 中华流行病学杂志

Objective To evaluate the relations between hypertensive disorders (HDP) in pregnancy and early-term birth.Methods A total of 3 474 pregnant women were consecutively recruited.Demographic information was collected in early pregnancy.HDP was diagnosed in the first,second and third trimesters,respectively.On the basis of precise evaluation on gestation age,early-term birth was defined as gestational age of 37-38 weeks + 6 days.Logistic regression models were conducted to examine the associations between HDP and early-term birth.Results The current study included 3 260 pregnant women,with the rates of HDP,pregnancy-induced hypertension syndrome and pre-eclampsia as 6.0％ (n=194),4.2％ (n=137) and 1.8％ (n=57),respectively.After controlling for potential confounders,no significant differences between pregnancy-induced hypertension syndrome and early-term birth (OR=1.49,95％C1:0.94-2.36) were found.Pre-eclampsia appeared to have increased the risk of early-term birth (OR=4.46,95％ CI:2.09-9.54).Conclusion Pre-eclampsia could significantly increase the risk of early-term birth.This finding suggested that early detection and intervention programs were helpful in reducing the risk of early-term birth.

Relations between hypertensive disorders in pregnancy and subsequent risk of early-term birth:a birth cohort study / 中华流行病学杂志

Objective To evaluate the relations between hypertensive disorders (HDP) in pregnancy and early-term birth.Methods A total of 3 474 pregnant women were consecutively recruited.Demographic information was collected in early pregnancy.HDP was diagnosed in the first,second and third trimesters,respectively.On the basis of precise evaluation on gestation age,early-term birth was defined as gestational age of 37-38 weeks + 6 days.Logistic regression models were conducted to examine the associations between HDP and early-term birth.Results The current study included 3 260 pregnant women,with the rates of HDP,pregnancy-induced hypertension syndrome and pre-eclampsia as 6.0％ (n=194),4.2％ (n=137) and 1.8％ (n=57),respectively.After controlling for potential confounders,no significant differences between pregnancy-induced hypertension syndrome and early-term birth (OR=1.49,95％C1:0.94-2.36) were found.Pre-eclampsia appeared to have increased the risk of early-term birth (OR=4.46,95％ CI:2.09-9.54).Conclusion Pre-eclampsia could significantly increase the risk of early-term birth.This finding suggested that early detection and intervention programs were helpful in reducing the risk of early-term birth.

Recién nacido a término precoz: incidencia y morbilidad perinatal / Early term newborn: incidence and perinatal morbidity

La incidencia global de nacimientos a término antes de las 39 semanas ha aumentado, en parte por el auge de inducciones y cesáreas electivas antes de esta edad gestacional. Los neonatos a término precoces, aquellos nacidos entre 370/7 y 386/7 semanas, pueden tener mayor riesgo de complicaciones que los nacidos a partir de las 39 semanas. Determinar la incidencia denacimientos a término precoces y su asociación con complicaciones posnatales inmediatas. Estudio analítico de cohorte que abarcó una población de 2648 nacimientos; se estimó la incidencia de nacimientos a término precoces y su frecuencia de complicaciones posnatales. De los 2648 niños, 2144 nacieron a término. La incidencia general de nacimiento a término precoz fue 24% (635/2648), mientras que el 29,6% de todos los niños a término fue conformado por recién nacidos menores de 39 semanas (635/2144). El 16,3% (104/635) de éstos presentó alguna complicación aguda. Las causas primarias de admisión fueron las enfermedades respiratorias y la ictericia. En comparación a los nacidos a las 39 semanas, los niños a término precoces tuvieron mayor riesgo de complicaciones agudas (RR 2,1), morbilidad respiratoria (RR 4,1) y admisión a cuidados intensivos (RR 4,7). La incidencia de nacimientos a término antes de las 39 semanas es alta en nuestra poblaciòn. Los neonatos a término precoces representan un tercio de los nacidos a término y conllevan un riesgo aumentado de complicaciones. Se requieren medidas preventivaspara evitar el nacimiento no indicado antes de las 39 semanas

The global incidence of early term births has increased worldwide, primarily because of a continuous increment ininductions and cesarean sections performed before 39 weeks’ gestation. Early term infants, defined as those born between 370/7 and 386/7 weeks, entail a higher risk of morbidity than their full term peers. To know the incidence of early term births and theirassociation with the risk of acute neonatal complications. A cohort observational study of 2648 newborn infants was undertaken. Incidence of early term infants and frequency of admissions for acute complications were measured. 2144 infants of the whole population were full-term infants. Total incidence of early term birth was 24% (635/2648). Early term newborns represented 29.6% of all term infants (635/2144). 104 (16.3%) of all early term infants had to be admitted because of complications. Main causes ofadmission were respiratory distress and jaundice. Early term infants had an increased risk of acute complications (RR 2.1), respiratory morbidity (RR 4.1) and admission to intensive care (RR 4.7). Conclusions: The incidence of early term births in our institution is high. Early term infants have a definite risk of complications. Greater attention needs to be paid to the prevention of non-indicated births before 39 weeks’ gestation