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1.
Article | IMSEAR | ID: sea-185577

ABSTRACT

BACKGROUND– Work output of an employee is dependent on the job satisfaction level and is an important criterion as its effect has an indirect impact on the society. A study on job satisfaction level of faculties in Government Medical Colleges would help in the betterment of the Medical Education System in India as it would bring out factors that affect the performance of medical teachers. METHODS-- 100 structured questionnaires, based on 'The Minnesota Satisfaction Questionnaire', were distributed among faculties, which were duly filled up by the participants and the data from the questionnaires were statistically analyzed. RESULT--According to the grade of satisfaction level, it was found that 4.4% were extremely satisfied, 21.1% were very satisfied , 37.8% were satisfied, 30% were somewhat satisfied, , 5.5% were not satisfied, and 1.2% was indecisive. CONCLUSION—Transfer, low salary, disparity in infrastructure is instigating medical teachers to join different private medical colleges.

2.
Article | IMSEAR | ID: sea-198372

ABSTRACT

Introduction: Greater palatine foramen is a very important landmark for administering anesthesia in maxillofacialand dental surgeries. Getting the anesthesia correct each time is a technical manoeuvre, which require sufficientamount of clinical skill and experience. The anatomical landmark has been described by many authors but asper the data in the eastern Indian population it is sparse. This study aims to define the greater palatine foramenaccording to various landmarks.Materials and Methods: One hundred and three skulls from two medical colleges of eastern India were studiedby the first and second authors separately and consecutively. All the skulls were examined for any broken partsin the hard palate and in the greater palatine foramen region. Only the skulls that were intact in these areas wereconsidered for the study.Result: The mean distance of the greater palatine foramen to the incisive foramen was 35.45mm in the males and34.82mm in the females. The average distance between the greater palatine foramen and the midline maxillarysuture was 13.22mm in the males and 12.98 mm in the females. In 85.92% cases we found the GPF to be oval inshape and it opened in to the oral cavity antero-medially in 58% of the cases. With respect to the molar teeth, in42.71% of the cases the greater palatine foramen was present opposite the anterior ½ of the 3rd molar.

3.
Article in English | IMSEAR | ID: sea-181929

ABSTRACT

Background: The stage of infancy lasts from birth to 12 months of age (WHO).Infant Dermatosis is quite different from adult dermatosis.The objective of our study is to find out various patterns of infant dermatosis in eastern India. Methods: The cross sectional study was done in Nilratan sircar Medical college & Hospital for a period of one year (April 2015 to March 2016). The study was carried out on 600 infants. As per different patterns of skin manifestations, the infants were divided into two groups - neonatal and post neonatal. After studying the individual infants’ history, the relevant clinical examinations and investigations(clinically doutful cases) were carried out.Diseases were tabulated accordingly. Results: In neonatal group physiological conditions were predominant (65.3%) whereas infections were prevalent in post neonatal period (54.8%). Among the infectious conditions parasitic infections (25.3%) were most common followed by bacterial (12.2%), viral(10.2%),and fungal infections (7.1%). Sweat gland disorders (14.5%) were commonest after infections and prevalent in older age group. Seborrheic dermatitis was commonest among dermatitis and equally prevalent in both groups (10%). Conclusion: Infants are vulnerable to various types of infections (bacterial,viral,fungal).Infected family members may be source of chronicity of infections.Though various physiological conditions are very common in neonatal age group which needs proper explanation and counseling of parents. Infections and non infectious dermatitis are also prevalent which need proper treatment.

4.
Indian J Pathol Microbiol ; 2014 Apr-Jun 57 (2): 236-243
Article in English | IMSEAR | ID: sea-156021

ABSTRACT

Background: The hereditary hemoglobin (Hb) disorders are the most commonly encountered single gene disorders in India. Data pertaining to the pattern of hemoglobinopathies and thalassemias is scarce in North East India, and hence it was considered worthwhile to study these disorders using a large series of patients referred to a clinical diagnostic laboratory. Aims: A total of 9000 patients referred for Hb variant analysis were studied to identify hemoglobinopathies and thalassemias in Upper Assam region of North East India. Materials and Methods: This study was performed by high performance liquid chromatography (HPLC) using BIORAD variant Hb typing system. Results: Out of 9000 patients studied, abnormal Hb fractions were seen in 5320 patients. The HbE gene was detected in 4315 patients of which HbE trait was seen in 2294 followed by HbE disease in 1892. There were 114 HbE beta thalassemia patients and 15 double heterozygotes of HbE with HbS or HbD. Beta thalassemia trait was seen in 313 patients and beta thalassemia homozygous in 32. HbS gene was detected in 460 patients comprising of HbS trait in 189, HbS disease in 203, S beta thalassemia in 53 and double heterozygotes of SD and ES in 15. The rest comprised of HbD trait in 6, delta beta thalassemia in 33, hereditary persistence of fetal hemoglobin trait in 5 and J chain hemoglobinopathy in 8 patients. Evidence of alpha thalassemia though suspected, could not be confi rmed. Conclusion: A high incidence of hemoglobinopathies and thalassemias and their combinations is unique for this part of the country.

5.
Article in English | IMSEAR | ID: sea-154045

ABSTRACT

Background: Although extensively studied in adults, Nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity in children, especially in young children, remains a poorly defined area in both its clinical and epidemiologic aspects. Methods: The present observational study was conducted in the department of Dermatology of a tertiary care hospital in Eastern India. Twenty children (20) were screened with suspected NSAID-associated fixed drug eruption (FDE) in the outpatient department. A thorough history taking and clinical examination was performed for each of the cases of FDE. These cases were then managed conservatively after discontinuation of the suspected medication. Rechallenge with the putative offending drug was not done due to ethical reasons. WHO-UMC Causality Assessment criteria and Naranjo probability scale were used for causality assessment of each of the cases of FDE. The severity of reported reactions was assessed by using Modified Hartwig and Siegel Scale and Preventability of the ADRs was assessed by Modified Schumock and Thornton Scale. Results: Patients aged between 5 to 12 years and with a male preponderance of 3:2. The offending NSAID was ibuprofen for 8 of the patients, paracetamol and diclofenac for 4 each and ketorolac for 4 of the patients. These patients were prescribed the offending drugs for fever, rheumatoid arthritis and minor trauma. For each patient, history and clinical signs was consistent with the diagnosis of drug-induced FDEs. Causality assessment for each of the cases revealed ‘possible’ association predominantly (80%). Severity of the suspected ADR (adverse drug reaction) assessed using Modified Hartwig and Siegel Scale, revealed that the ADRs were mild(30%) to moderate (70%) in severity and of ‘probable’ preventibility (90%). Conclusions: 20 new cases of NSAID-induced FDEs over a period of 6 months suggest that this is not a rare entity as was presumed. There is a growing need for a strict monitoring of such off label offending drugs, known to cause ADRs especially among pediatric patients to ensure safe and rational therapeutics.

6.
Indian J Pediatr ; 2009 Oct; 76(10): 1007-1012
Article in English | IMSEAR | ID: sea-142394

ABSTRACT

Objective. To determine the pattern of deletions of the dystrophin gene, the major class of mutations among the Duchenne and Becker muscular dystrophy patients of eastern India and to analyze the carrier frequency of the female members of the proband’s family. Methods. Deletional mutations occurring in patients have been characterized by multiplex polymerase chain reaction. Carrier state of mothers and sisters of probands were analyzed by either of two methods: 1) typing polymorphic short tandem repeat markers in or around the regions of deletion, by radioactive polymerase chain reaction and 2) quantitative real time amplification of the region of deletion. Results. Deletions were detected in 67 (62.04%) out of 108 male patients, about 76.12% of these being localized in the central hot spot region of the gene, i.e., between exon 42 to exon 53 and 17.91% at the proximal hot spot i.e., between exon 1 to exon 20. In the present study were found 43 types of deletions, out of which 25 (58%) were new deletions, which were not described earlier among the Indian patients. Distribution pattern of deletions in different hot spot regions has been compared with that of other countries and statistical analysis reveals significant difference between countries (p<0.001). Correlation of the pattern of deletion with clinical phenotype of patients has been discussed. Interesting case of germline mosaicism and its implications in counseling has also been discussed. Conclusion. About half the mothers of affected probands were not carriers of the deletion, underscoring the need to use real time techniques for carrier detection.


Subject(s)
Adolescent , Adult , Age Distribution , Age of Onset , Child , Child, Preschool , Cross-Sectional Studies , DNA Mutational Analysis , Dystrophin/genetics , Female , Genetics, Population , Germ-Line Mutation/genetics , Health Surveys , Heterozygote , Humans , Incidence , India/epidemiology , Male , Middle Aged , Muscular Dystrophy, Duchenne/diagnosis , Muscular Dystrophy, Duchenne/epidemiology , Muscular Dystrophy, Duchenne/genetics , Polymerase Chain Reaction , Risk Assessment , Sequence Deletion/genetics , Sex Distribution , Young Adult
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