ABSTRACT
Rhei Radix et Rhizoma is one of the most important Chinese medicinal materials in China, which is also a typical representative herb with multiple effects, multiple species, and multiple genuine production areas. In this paper, the chemical constituents of Rhei Radix et Rhizoma were systematically summed up, and the progress of the chemical research on Rhei Radix et Rhizoma based on different varieties, different habitats, different harvest periods, and different tissues were analyzed. The attention to regional change and harvest time, the application of “efficacy bias” for different varieties, the utilization of “non medicinal tissues”, and the high value development of resource components were proposed. The utilization ways and strategies provide important reference for the comprehensive development and utilization of rhubarb resources.